植物转录因子NAP亚家族的研究进展

doi:10.3864/j.issn.0578-1752.2014.02.001

Abstract

Abstract: NAP (NAC-Like，Activated by AP3/PI) is a plant-specific transcription factor, which plays an important role in regulation of plant growth and development, leaf senescence and responses to various kinds of stresses. NAP belongs to NAC (NAM, ATAF1/2 and CUC2) transcription factor, which contains a conserved N-terminal NAC domain and a highly divergent transcription activation region (TAR) in C-terminal region. Furthermore, the NAP protein is localized in the nucleus, and the NAP gene structure contains three exons and two introns. Since the first NAP was found to be closely associated with Arabidopsis flower growth and development in 1998, NAP subfamily has been discovered in rice, wheat, cotton, bean, bamboo, grape and so on, which further confirms that NAP subfamily is one of plant-specific transcription factors. Moreover, NAP subfamily has various biological functions. Firstly, NAP participates in the plant growth and development including seed, root and flower. Then NAP subfamily also takes an essential part in the leaf senescence, which indirectly regulates the macromolecules degradation and nutrient-recycling processes. NAP subfamily also responds to stresses such as drought, salt and cold. And then, NAP subfamily can contribute to the improvement of crop quality, which provides a novel method for crop breeding. In the recent researches, it was supposed that NAP is mainly regulated by abscisic acid (ABA) and ethylene, and a Golgi-localized protein phosphatase 2C SAG113 is its direct target gene. Subsequently, as a negative regulator of ABA signal transduction, SAG113 is closely related to the control of water loss especially during leaf senescence. The results indicate that NAP is regulated by ABA and specifically interacts with its target gene (SAG113). Through ABA-NAP-SAG113 PP2C regulatory chain, NAP will promote the expression of its target gene (SAG113). Then the SAG113 expression inhibits the stomatal closure, which leads to water loss and enough oxygen diffusion for ethylene-stimulated fast respiration during leaf senescence. All the results in turn trigger leaf senescence. The study on NAP subfamily will have an effect on both theoretical and practical researches.

Key words: NAP , structure , biological function , regulated mechanism

FAN Kai, WANG Xue-De, YUAN Shu-Na, WANG Ming. Recent Advances in Research of Transcription Factor NAP Subfamily in Plants[J].Scientia Agricultura Sinica, 2014, 47(2): 209-220.

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