Abstract: Variations of structural loci among 4 sheep populations in China were examined by the method of multiloci electrophoresis,and alike data from 11 sheep populations were quoted to analysis the genetic structure of native sheep populations in East and South Asia.The average heterozygosity and effective number of alleles among 15 populations were 0.2746 and 1.559 respectively.Mongolian sheep possed the largest genetic diversity while Chinese, Vietnamese,Bangladeshi and Nepalese populations diminished take their turns. Coefficients of genetic differentiation were between 0.0126 and 0.3083, the average was 0.148 which demonstrated that genetic variations lied in populations and possed total 85.2 %. Genetic identity and genetic distances all showed relative low genetic differentiation.There had no relevance between geographical distances and genetic distances.Gene flow was smooth between most populations which leaded to inconsistency between geographical distances and genetic distances.15 native sheep populations in East and South Asia can be divided into two groups,one group including part Chinese and Mongolian populations,another including Yunnan of China,part Nepalese and Bangladeshi populations.Other populations did not cluster together and went into above-mentioned two groups.

Key words: Sheep populations, Genetic structure, Phylogenetic relationship, Gene flow