药用柑橘应用研究现状与前景

doi:10.3864/j.issn.0578-1752.2026.20.009

Abstract

Abstract:

In addition to fresh consumption, juicing, and essential oil extraction, citrus is also an important botanical source in traditional Chinese medicine. With a history of medicinal use spanning over two millennia, their therapeutic effects are attributed to diverse bioactive compounds, including flavonoids, volatile components, alkaloids, coumarins, limonoids, and polysaccharides, which collectively contribute to antioxidant, anti-inflammatory, and anticancer activities. However, the composition and levels of these active components are influenced by multiple factors, such as germplasm, environment, developmental stage, and tissue type, resulting in considerable variation in efficacy among different genotypes, origins, and harvest periods. Despite widespread recognition of its medicinal and health benefits, research remains limited in several key areas, including the accurate identification of botanical origins, systematic characterization of bioactive components, establishment of official quality evaluation standards, and exploration of novel germplasm resources. This review systematically examined the medicinal citrus germplasm resources, medicinal tissues, and their primary functional components, focusing on the material basis of efficacy and fundamental evaluation indicators. Future research prospects were also proposed concerning quality assessment system improvement, accurate germplasm identification, novel resource exploitation and standardized personalized medicinal application. Collectively, this review provides a theoretical foundation for improving the quality control of medicinal citrus, promoting the discovery and utilization of novel germplasms, and facilitating the development of industry-wide regulatory standards.

Key words: medicinal citrus, source plant, bioactive constituent, comprehensive evaluation, germplasm exploration and innovation

LIU ZeYang, LIANG YaNing, CHEN Qi, TAN MengQi, ZHANG HuiXian, YUAN ZiYu, YANG Yong, ZHANG Fei, XU Qiang, DENG XiuXin, CHEN JiaJing, XU Juan. Research Progress and Prospect of Medicinal Citrus Application[J].Scientia Agricultura Sinica, 2026, 59(20): 4547-4569.

Figures/Tables 7

Fig. 1

Table 1

Summary of original plants, medicinal parts and Chinese patent medicines of medicinal citrus in the Chinese Pharmacopoeia"

药材名 Medicinal material name	基原植物 Original plant source	品种群 Cultivar group	入药组织/部位 Medicinal part or tissue	含量标准 Content standard	功能与主治 Function and indication	中成药数量（不完全统计） Number (Incomplete statistics)
陈皮 Chenpi	橘及其栽培变种 Citrus reticulata and its cultivated varieties	茶枝柑、大红袍、温州蜜柑、福橘 Chachi, Dahongpao, Unshiu, Fuju	干燥成熟果皮 Dried ripe pericarp	陈皮：橙皮苷≥3.5%，广陈皮：橙皮苷≥2.0%，川陈皮素和橘皮素≥0.42% Chenpi: Hesperidin≥3.5%, Guangchenpi: Hesperidin≥2.0%, Nobiletin and tangeretin≥0.42%	理气健脾，燥湿化痰；用于脘腹胀满，食少吐泻，咳嗽痰多 Regulate qi and strengthen the spleen, dry dampness and transform phlegm. It is indicated for abdominal distension and fullness, poor appetite with vomiting and diarrhea, as well as cough with profuse phlegm	186
青皮 Qingpi	橘及其栽培变种 Citrus reticulata and its cultivated varieties	/	干燥幼果或未成熟果实的果皮 Dried pericarp of young or unripe fruits	橙皮苷≥5.0% Hesperidin≥5.0%	疏肝破气，消积化滞；用于胸胁胀痛，疝气疼痛，乳癖，乳痈，食积气滞，脘腹胀痛 Soothe the liver, break stagnant qi, resolve accumulation, and transform stagnation. Chest and hypochondriac distending pain, hernia pain, breast hyperplasia (mammary nodule), acute mastitis, food accumulation with qi stagnation, and epigastric and abdominal distending pain	33
橘红 Juhong	橘及其栽培变种 Citrus reticulata and its cultivated varieties	大红袍、福橘 Dahongpao, Fuju	干燥外层果皮 Dried exocarp	橙皮苷≥1.7% Hesperidin≥1.7%	理气宽中，燥湿化痰；用于咳嗽痰多，食积伤酒，呕恶痞闷 Regulate qi, broaden the middle, dry dampness, and transform phlegm. Cough with profuse sputum, food accumulation due to alcohol abuse, nausea, vomiting, and stuffy oppression	11
橘核 Juhe	橘及其栽培变种 Citrus reticulata and its cultivated varieties	大红袍、福橘 Dahongpao, Fuju	干燥成熟种子 Dried mature seed	/	理气，散结，止痛；用于疝气疼痛，睾丸肿痛，乳痛乳癖 Regulate qi, dissipate nodules, and relieve pain. Hernia pain, testicular swelling and pain, breast pain, and breast hyperplasia (mammary nodules)	1
橘叶Juye	/	/	/	/	/	3
化橘红 Huajuhong	化州柚或柚 Citrus grandis Tomentosa or Citrus grandis	/	未成熟或近成熟的干燥外层果皮 Dried immature or nearly ripe fruit exocarp	柚皮苷≥3.5% Naringin≥3.5%	理气宽中，燥湿化痰；用于咳嗽痰多，食积伤酒，呕恶痞闷 Regulate qi, broaden the middle, dry dampness, and transform phlegm. Cough with profuse sputum, food accumulation due to alcohol abuse, nausea, vomiting, and stuffy oppression	12
枳实 Zhishi	酸橙及其栽培变种或甜橙 Citrus aurantium and its cultivated varieties, or Citrus sinensis	黄皮、代代花、朱栾、塘橙 Huangpi, Daidai, Chuluan, Tangcheng	干燥幼果 Dried young fruit	辛弗林≥0.3% Synephrine≥0.3%	破气消积，化痰散痞；用于积滞内停，痞满胀痛，泻痢后重，大便不通，痰滞气阻，胸痹，结胸，脏器下垂 Break stagnant qi, eliminate accumulation, transform phlegm, and dissipate stuffiness. Internal accumulation of undigested food and qi stagnation, stuffiness and distending pain, tenesmus in dysentery, constipation, phlegm stagnation with qi blockage, chest impediment (thoracic obstruction), chest binding (fullness and pain in the chest), and visceral ptosis	47
枳壳 Zhiqiao	酸橙及其栽培变种 Citrus aurantium and its cultivated varieties	黄皮、代代花、朱栾、塘橙 Huangpi, Daidai, Chuluan, Tangcheng	干燥未成熟果实 Dried immature fruit	柚皮苷≥4.0% 新橙皮苷≥3.0% Naringin≥4.0% Neohesperidin≥3.0%	理气宽中，行滞消胀；用于胸胁气滞，胀满疼痛，食积不化，痰饮内停，脏器下垂 Regulate qi, broaden the middle, unblock stagnation, and relieve distension. Qi stagnation in the chest and hypochondrium, distension and pain, food accumulation with indigestion, internal retention of phlegm-fluid, and visceral ptosis	79
香橼 Xiangyuan	枸橼或香圆 Citrus medica or Citrus wilsonii	/	干燥成熟果实 Dried ripe fruit	香圆：柚皮苷≥2.5% 枸橼未作具体指标要求 Xiangyuan: Naringin≥2.5% Citron: No specific requirement.	疏肝理气，宽中，化痰；用于肝胃气滞，胸胁胀痛，脘腹痞满，呕吐噫气，痰多咳嗽 Soothe the liver, regulate qi, broaden the middle, and transform phlegm. Qi stagnation of the liver and stomach, chest and hypochondriac distending pain, epigastric and abdominal stuffiness, vomiting and eructation, and profuse cough with sputum	6
佛手 Foshou	佛手 C. medica var. sarcodactylis	/	干燥果实 Dried fruit	橙皮苷≥0.03% Hesperidin≥0.03%	疏肝理气，和胃止痛，燥湿化痰；用于肝胃气滞，胸胁胀痛，胃脘痞满，食少呕吐，咳嗽痰多 Soothe the liver, regulate qi, harmonize the stomach, relieve pain, dry dampness, and transform phlegm. Qi stagnation of the liver and stomach, chest and hypochondriac distending pain, epigastric stuffiness, poor appetite, vomiting, and cough with profuse sputum	10

Table 1

Fig. 2

Table 2

Potential pharmacodynamic components and their pharmacological activities in medicinal citrus"

序号 No.	潜在药效成分 Potential active constituent	化学分类 Chemical classification	药理作用 Pharmacological action	实验模型 Experimental model	参考文献 Reference
1	柚皮素 Naringenin	类黄酮 Flavonoids	抗氧化、降血糖血脂、抗肥胖、抗糖尿病、抗炎、抗器官毒性 Antioxidant, hypoglycemic and lipid-lowering, anti-obesity, antidiabetic, anti-inflammatory, and anti-organ toxicity	大鼠、小鼠 Rat, mouse	[14]
2	圣草酚Eriodictyol		抗炎、保护神经系统Anti-inflammatory and neuroprotective	大鼠Rat	[15]
3	芹菜素 Apigenin		抗氧化、抗炎、抗癌、降血糖血脂、延缓衰老、减轻焦虑 Antioxidant, anti-inflammatory, anticancer, hypoglycemic and lipid-lowering, anti-aging, and anxiolytic	细胞、大鼠、小鼠 Cell, rat, mouse	[16-18]
4	木犀草素Luteolin		抗炎Anti-inflammatory	小鼠Mouse	[19]
5	香叶木素Diosmetin		抗炎Anti-inflammatory	小鼠Mouse	[20]
6	四甲氧基木犀草素 Tetramethoxyluteolin		调节免疫 Immunomodulatory	细胞 Cell	[21]
7	香蜂草苷Didymin		保护肝脏Hepatoprotective	小鼠Mouse	[22]
8	芸香柚皮苷Narirutin		抗癌、神经保护Anticancer and neuroprotective	大鼠Rat	[23-24]
9	地奥司明 Diosmin		抗炎、抗氧化、抗糖尿病、抗癌、保护肝脏、保护神经系统、保护视网膜 Anti-inflammatory, antioxidant, antidiabetic, anticancer, hepatoprotective, neuroprotective, and retinoprotective	大鼠、小鼠 Rat, mouse	[25]
10	野漆树苷 Rhoifolin		抗糖尿病、抗癌、抗氧化、抗炎 Antidiabetic, anticancer, antioxidant, anti-inflammatory	小鼠、大鼠 Mouse, rat	[26-27]
11	甜橙黄酮 Sinensetin		抗炎、降血糖血脂、抗肥胖 Anti-inflammatory, hypoglycemic and lipid-lowering, anti-obesity	大鼠、小鼠 Rat, mouse	[28-29]
12	异甜橙黄酮 Isosinensetin		抗氧化、抗癌 Antioxidant, anticancer	小鼠、细胞 Mouse, cell	[30-31]
13	芹菜素三甲醚 Apigenin trimethyl ether		治疗房颤 Treatment of atrial fibrillation	小鼠 Mouse	[32]
14	异欧前胡素 Isoimperatorin	香豆素类 Coumarins	抑制肿瘤血管生成、预防糖尿病、预防和治疗甲型流感病毒 Inhibit tumor angiogenesis, prevent diabetes, prevent and treat influenza A virus	细胞 Cell	[33-34]
15	佛手柑内酯Bergapten		抗炎、抗衰老Anti-inflammatory, anti-aging	细胞Cell	[35]
16	花椒毒酚Xanthotoxol		抗炎Anti-inflammatory	细胞Cell	[36]
17	伞形酮Umbelliferone		抗炎Anti-inflammatory	小鼠Mouse	[37]
18	异橙皮内酯Isomeranzin		抗炎Anti-inflammatory	细胞Cell	[38]
19	橙皮油素 Auraptene		抗癌、抗抑郁、预防心肌梗死、调节免疫、改善人体认知障碍 Anticancer, antidepressant, prevent myocardial infarction, immunomodulatory, improve cognitive impairment in humans	细胞、小鼠、大鼠、人体 Cell, mouse, rat, human	[39-41]
20	异茴芹素 Isopimpinellin		抗癌、抑制肿瘤血管生成 Anticancer, inhibit tumor angiogenesis	小鼠、细胞、斑马鱼 Mouse, cell, zebrafish	[42]
21	马尔敏Marmin		促进脂肪细胞凋亡、降脂Promote adipocyte apoptosis, lipid-lowering	细胞Cell	[43]
22	欧前胡素Imperatorin		减轻心肌损伤Reduce myocardial injury	小鼠Mouse	[44]
23	滨蒿内酯Scoparone		保护肝脏Hepatoprotective	小鼠Mouse	[45]
24	丁香酚 Eugenol	苯丙素类 Phenylpropanoids	抗氧化、抗癌、抗糖尿病、抗肥胖、心血管保护、抗炎、镇痛、保护神经系统 Antioxidant, anticancer, antidiabetic, anti-obesity, cardiovascular protection, anti-inflammatory, analgesic, neuroprotective	小鼠、大鼠、斑马鱼 Mouse, rat, zebrafish	[46]
25	邻百里香酚Thymol		抗癌Anticancer	小鼠Mouse	[47]
26	茴香脑Anethole		保护神经系统Neuroprotective	小鼠Mouse	[48]
27	对香豆酸 p-Coumaric acid		抗氧化、抗炎、抑制肿瘤血管生成 Antioxidant, anti-inflammatory, inhibit tumor angiogenesis	小鼠、大鼠 Mouse, rat	[49-50]
28	2-蒈烯2-Carene	单萜 Monoterpene	抗癌Anticancer	大鼠Rat	[51]
29	β-月桂烯 β-Myrcene		抗氧化、抗衰老、抗炎、抗癌 Antioxidant, anti-aging, anti-inflammatory, anticancer	大鼠、细胞 Rat, cell	[52-53]
30	d-柠檬烯d-Limonene		抗抑郁Antidepressant	小鼠Mouse	[54]
31	3-蒈烯3-Carene		促进睡眠Promote sleep	小鼠Mouse	[55]
32	橙花醛Neral		抗炎Anti-inflammatory	细胞Cell	[56]
33	柠檬醛Citral		抗炎Anti-inflammatory	细胞Cell	[56]
34	α-松油醇 α-Terpineol		抗炎、抗氧化、抗癌 Anti-inflammatory, antioxidant, anticancer	大鼠、细胞 Rat, cell	[57]
35	(R)-芳樟醇 (R)-Linalool		抗氧化、保护神经系统Antioxidant, neuroprotective	细胞Cell	[58]
36	香叶醇 Geraniol		抗氧化、保护神经、抗炎 Antioxidant, neuroprotective, anti-inflammatory	大鼠、小鼠 Rat, mouse	[59-60]
37	松油烯-4-醇Terpinen-4-ol		抗氧化Antioxidant	细胞Cell	[61]
38	氧化芳樟醇 Linalool oxide		抗焦虑Anxiolytic	小鼠Mouse	[62]
39	橙花叔醇 Nerolidol	倍半萜 Sesquiterpene	抗氧化、抗人体溃疡病、抗癌 Antioxidant, anti-ulcer, anticancer	大鼠、细胞 Rat, cell	[63-64]
40	β-石竹烯 β-Caryophyllene		抗炎、抗氧化、抗癌、保护心肌、降血糖血脂 Anti-inflammatory, antioxidant, anticancer, cardioprotective, hypoglycemic and lipid-lowering	大鼠、细胞、小鼠 Rat, cell, mouse	[65]
41	α-蛇麻烯α-Humulene		抗炎Anti-inflammatory	小鼠Mouse	[66]
42	δ-杜松烯δ-Cadinene		抑制癌细胞增殖、诱导凋亡Inhibit cancer cell proliferation, induce apoptosis	细胞Cell	[67]
43	氧化石竹烯 Caryophyllene oxide		抑制癌细胞增殖、诱导凋亡 Inhibit cancer cell proliferation, induce apoptosis	细胞 Cell	[68]
44	奥巴叩酮 Obacunone	三萜 Triterpene	预防肥胖和高血糖、抑制癌细胞增殖和抗癌 Prevent obesity and hyperglycemia, inhibit cancer cell proliferation and anticancer	小鼠、细胞 Mouse, cell	[69-70]
45	柠檬苦素 Limonin		抗癌、抗炎、镇痛、抗菌抗病毒、抗氧化、保护肝脏 Anticancer, anti-inflammatory, analgesic, antibacterial and antiviral, antioxidant, hepatoprotective	小鼠、细胞 Mouse, cell	[71-73]
46	诺米林 Nomilin		抗抑郁、预防骨骼异常发育疾病、延长寿命 Antidepressant, prevent abnormal bone development diseases, prolong lifespan	小鼠 Mouse	[74-75]
47	木栓酮Friedelin		抑制癌细胞增殖Inhibit cancer cell proliferation	细胞Cell	[76]
48	叶黄素 Lutein	四萜 Tetraterpene	改善人体认知障碍、改善视力、抑制动脉粥样硬化 Improve cognitive impairment in humans, improve vision, inhibit atherosclerosis	人体 Human	[77-78]
49	玉米黄质Zeaxanthin		改善人体认知障碍Improve cognitive impairment in humans	人体Human	[79]
50	新叶黄素Neoxanthin		抗癌、抗氧化、抗肥胖Anticancer, antioxidant, anti-obesity	细胞Cell	[80]
51	番茄红素 Lycopene		抗癌、降血糖、抗炎、保护肝脏 Anticancer, hypoglycemic, anti-inflammatory, hepatoprotective	细胞、人体 Cell, human	[81]
52	β-胡萝卜素β-Carotene		抗炎Anti-inflammatory	细胞Cell	[82]
53	N-甲基酪胺 N-Methyltyramine	生物碱 Alkaloid	促进营养消化、减肥、治疗胃肠道疾病 Promote nutrient digestion, weight loss, treat gastrointestinal diseases	大鼠、小鼠 Rat, mouse	[83-84]
54	水苏碱 Stachydrine		抗纤维化、抗癌、抗炎、心血管保护 Antifibrotic, anticancer, anti-inflammatory, cardiovascular protection	大鼠、细胞 Rat, cell	[85]
55	8-羟基喹啉 8-Hydroxyquinoline		抗癌 Anticancer	细胞 Cell	[86]
56	β-谷甾醇 β-Sitosterol	甾醇类 Sterols	抗癌、抗糖尿病 Anticancer, antidiabetic	小鼠、大鼠 Mouse, rat	[87-88]
57	腐胺 Putrescine	多胺类Polyamines	抗抑郁 Antidepressant	小鼠 Mouse	[89]

Table 2

Fig. 3

Fig. 4

Fig. 5

References 134

[1]	Huang Y, He J X, Xu Y T, Zheng W K, Wang S H, Chen P, Zeng B, Yang S Z, Jiang X L, Liu Z S, Wang L, Wang X, Liu S J, Lu Z H, Liu Z A, Yu H W, Yue J Q, Gao J Y, Zhou X Y, Long C R, et al. Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in Citrus fruits[J]. Nature Genetics, 2023, 55(11): 1964-1975. doi: 10.1038/s41588-023-01516-6 pmid: 37783780
[2]	国家药典委员会. 中华人民共和国药典-一部: 2025年版[M]. 北京: 中国医药科技出版社, 2025. Chinese Pharmacopoeia Commission. People’s Republic of China
	( PRC) Pharmacopoeia-part I: 2025 edition[M]. Beijing: China Medical Science Press, 2025. (in Chinese)
[3]	Huang H T, Liu Y, Su J M, Liang X X, Wu H, Bai M. Evaluation of the authenticity of Citri grandis exocarpium based on metabolomics and transcriptomics[J]. Medicinal Plant Biology, 2025, 4(1): e006.
[4]	李泮霖, 彭维, 吴灏, 王永刚, 李沛波, 张迷迷, 苏薇薇. 化橘红药典标准的修改建议及其等级标准的建立[J]. 中山大学学报(自然科学版), 2019, 58(6): 1-13.
	Li P L, Peng W, Wu H, Wang Y G, Li P B, Zhang M M, Su W W. Suggestions for the quality standard in Chinese pharmacopoeia of Citri Grandis Exocarpium and the establishment of its grade standard[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 2019, 58(6): 1-13. (in Chinese)
[5]	Li C Y, Schluesener H. Health-promoting effects of the Citrus flavanone hesperidin[J]. Critical Reviews in Food Science and Nutrition, 2017, 57(3): 613-631. doi: 10.1080/10408398.2014.906382
[6]	Chen J, Qin X, Chen M Y, Chen T Z, Chen Z, He B H. Biological activities, Molecular mechanisms, and Clinical application of Naringin in Metabolic syndrome[J]. Pharmacological Research, 2024, 202: 107124. doi: 10.1016/j.phrs.2024.107124
[7]	Bajgai B, Suri M, Singh H, Hanifa M, Bhatti J S, Randhawa P K, Bali A. Naringin: A flavanone with a multifaceted target against sepsis-associated organ injuries[J]. Phytomedicine, 2024, 130: 155707. doi: 10.1016/j.phymed.2024.155707
[8]	Akhter S, Arman M S I, Abu Tayab M, Islam M N, Xiao J B. Recent advances in the biosynthesis, bioavailability, toxicology, pharmacology, and controlled release of Citrus neohesperidin[J]. Critical Reviews in Food Science and Nutrition, 2024, 64(15): 5073-5092. doi: 10.1080/10408398.2022.2149466
[9]	Raza W, Luqman S, Meena A. Prospects of tangeretin as a modulator of cancer targets/pathways[J]. Pharmacological Research, 2020, 161: 105202. doi: 10.1016/j.phrs.2020.105202
[10]	Wang W Q, Jia T Q, Zhang Y F, Zhou Y W. Progress of researches on pharmacological effects and bioavailability of tangeretin[J]. Journal of Oleo Science, 2025, 74(1): 13-23. doi: 10.5650/jos.ess24169 pmid: 39756989
[11]	Qin Y Q, Yang J F, Li H B, Li J S. Recent advances in the therapeutic potential of nobiletin against respiratory diseases[J]. Phytomedicine, 2024, 128: 155506. doi: 10.1016/j.phymed.2024.155506
[12]	Kulawik M, Bajewska K, Kulawik A. P-Synephrine: An overview of physicochemical properties, toxicity, biological and pharmacological activity[J]. EXCLI Journal, 2025, 24: 381-400. doi: 10.17179/excli2024-8088 pmid: 40376440
[13]	Ru J L, Li P, Wang J N, Zhou W, Li B H, Huang C, Li P D, Guo Z H, Tao W Y, Yang Y F, Xu X, Li Y, Wang Y H, Yang L. TCMSP: A database of systems pharmacology for drug discovery from herbal medicines[J]. Journal of Cheminformatics, 2014, 6(1): 13. doi: 10.1186/1758-2946-6-13
[14]	Karim N, Jia Z Q, Zheng X D, Cui S L, Chen W. A recent review of Citrus flavanone naringenin on metabolic diseases and its potential sources for high yield-production[J]. Trends in Food Science & Technology, 2018, 79: 35-54.
[15]	冯海艳, 张越, 王艺, 陈卓琳, 陈雨霏, 高歌, 赵旸, 刘翠. 圣草酚对缺氧缺血性脑病新生大鼠的脑保护作用及机制研究[J]. 天然产物研究与开发, 2025, 37(9): 1698-1705. doi: 10.16333/j.1001-6880.2025.9.012
	Feng H Y, Zhang Y, Wang Y, Chen Z L, Chen Y F, Gao G, Zhao Y, Liu C. Protective effects and mechanisms of eriodictyol on brain of neonatal rats with hypoxic-ischemic encephalopathy[J]. Natural Product Research and Development, 2025, 37(9): 1698-1705. (in Chinese)
[16]	Shukla S, Gupta S. Apigenin: A promising molecule for cancer prevention[J]. Pharmaceutical Research, 2010, 27(6): 962-978. doi: 10.1007/s11095-010-0089-7 pmid: 20306120
[17]	Ren B, Qin W W, Wu F H, Wang S S, Pan C, Wang L Y, Zeng B, Ma S P, Liang J Y. Apigenin and naringenin regulate glucose and lipid metabolism, and ameliorate vascular dysfunction in type 2 diabetic rats[J]. European Journal of Pharmacology, 2016, 773: 13-23. doi: 10.1016/j.ejphar.2016.01.002 pmid: 26801071
[18]	Kramer D J, Johnson A A. Apigenin: A natural molecule at the intersection of sleep and aging[J]. Frontiers in Nutrition, 2024, 11: 1359176. doi: 10.3389/fnut.2024.1359176
[19]	Kotanidou A, Xagorari A, Bagli E, Kitsanta P, Fotsis T, Papapetropoulos A, Roussos C. Luteolin reduces lipopolysaccharide-induced lethal toxicity and expression of proinflammatory molecules in mice[J]. American Journal of Respiratory and Critical Care Medicine, 2002, 165(6): 818-823. pmid: 11897650
[20]	Lee D H, Park J K, Choi J, Jang H, Seol J W. Anti-inflammatory effects of natural flavonoid diosmetin in IL-4 and LPS-induced macrophage activation and atopic dermatitis model[J]. International Immunopharmacology, 2020, 89: 107046. doi: 10.1016/j.intimp.2020.107046
[21]	Patel A B, Tsilioni I, Weng Z Y, Theoharides T C. TNF stimulates IL-6, CXCL8 and VEGF secretion from human keratinocytes via activation of mTOR, inhibited by tetramethoxyluteolin[J]. Experimental Dermatology, 2018, 27(2): 135-143. doi: 10.1111/exd.13461 pmid: 29105195
[22]	Yang J W, Zou Y, Chen J, Cui C, Song J, Yang M M, Gao J, Hu H Q, Xia L Q, Wang L M, Lv X Y, Chen L, Hou X G. Didymin alleviates metabolic dysfunction-associated fatty liver disease (MAFLD) via the stimulation of Sirt1-mediated lipophagy and mitochondrial biogenesis[J]. Journal of Translational Medicine, 2023, 21(1): 921. doi: 10.1186/s12967-023-04790-4
[23]	Funaguchi N, Ohno Y, La B L B, Asai T, Yuhgetsu H, Sawada M, Takemura G, Minatoguchi S, Fujiwara T, Fujiwara H. Narirutin inhibits airway inflammation in an allergic mouse model[J]. Clinical and Experimental Pharmacology and Physiology, 2007, 34(8): 766-770. pmid: 17600554
[24]	Chakraborty S, Basu S. Multi-functional activities of Citrus flavonoid narirutin in Alzheimer’s disease therapeutics: An integrated screening approach and in vitro validation[J]. International Journal of Biological Macromolecules, 2017, 103: 733-743. doi: S0141-8130(17)30967-4 pmid: 28528948
[25]	Zheng Y Z, Zhang R, Shi W M, Li L F, Liu H, Chen Z X, Wu L H. Metabolism and pharmacological activities of the natural health- benefiting compound diosmin[J]. Food & Function, 2020, 11(10): 8472-8492.
[26]	Ehsan M, Ahmed S, Majeed W, Iftikhar A, Iftikhar M, Abbas M, Mehmood T. Rhoifolin improves glycometabolic control in streptozotocin-induced diabetic rats by up-regulating the expression of insulin signaling proteins and down-regulating the MAPK/JNK pathway[J]. Pharmaceuticals, 2025, 18(3): 361. doi: 10.3390/ph18030361
[27]	Kiliç C S, Kisla M M, Amasya G, Sengel-Türk C T, Alagöz Z A, Gençler Özkan A M, Ates I, Gümüsok S, Herrera-Bravo J, Sharifi-Rad J, Calina D. Rhoifolin: A promising flavonoid with potent cytotoxic and anticancer properties: Molecular mechanisms and therapeutic potential[J]. EXCLI Journal, 2025, 24: 289-320.
[28]	Zhang M T, Jiang H, Ou S B, Qian M, Qi H M, Chen J P, Zeng X F, Bai W D, Xiao G S. Dietary sinensetin and polymethoxyflavonoids: Bioavailability and potential metabolic syndrome-related bioactivity[J]. Critical Reviews in Food Science and Nutrition, 2024, 64(27): 9992-10008. doi: 10.1080/10408398.2023.2219758
[29]	Ke Z L, Zhao Z Y, Zhao Y Y, Xu X D, Li Y, Tan S, Huang C, Zhou Z Q. PMFs-rich Citrus extract prevents the development of non- alcoholic fatty liver disease in C57BL/6J mice induced by a high-fat diet[J]. Journal of Functional Foods, 2018, 47: 28-39. doi: 10.1016/j.jff.2018.05.032
[30]	Qin Y W, Song D Z, Liao S J, Chen J C, Xu M L, Su Y G, Lian H Y, Peng H, Wei L H, Chen K, Xu J K, Zhao J M, Liu Q. Isosinensetin alleviates estrogen deficiency-induced osteoporosis via suppressing ROS-mediated NF-κB/MAPK signaling pathways[J]. Biomedicine & Pharmacotherapy, 2023, 160: 114347. doi: 10.1016/j.biopha.2023.114347
[31]	Du Q Z, Chen H. The methoxyflavones in Citrus reticulata Blanco cv. Ponkan and their antiproliferative activity against cancer cells[J]. Food Chemistry, 2010, 119(2): 567-572. doi: 10.1016/j.foodchem.2009.06.059
[32]	Liu Y, Xu X H, Liu Z, Du X L, Chen K H, Xin X, Jin Z D, Hu Y, Li G R, Jin M W. Effects of the natural flavone trimethylapigenin on cardiac potassium currents[J]. Biochemical Pharmacology, 2012, 84(4): 498-506. doi: 10.1016/j.bcp.2012.05.002 pmid: 22583923
[33]	Xu Y T, Xia D, Deng S, Liang M L. Isoimperatorin inhibits angiogenesis by suppressing VEGFR2 signaling pathway[J]. Cardiovascular Drugs and Therapy, 2025, 39(2): 275-286.
[34]	Lai Y N, Han T T, Zhan S F, Jiang Y, Liu X H, Li G. Antiviral activity of isoimperatorin against influenza a virus in vitro and its inhibition of neuraminidase[J]. Frontiers in Pharmacology, 2021, 12: 657826. doi: 10.3389/fphar.2021.657826
[35]	叶元兰, 刘恺文, 潘一鸣, 郭风劲. 佛手柑内酯延缓骨关节炎软骨细胞衰老[J]. 陆军军医大学学报, 2025, 47(3): 262-274.
	Ye Y L, Liu K W, Pan Y M, Guo F J. Bergapten alleviates senescence of chondrocytes in osteoarthritis[J]. Journal of Army Medical University, 2025, 47(3): 262-274. (in Chinese)
[36]	Lee Y, Hyun C G. Anti-inflammatory effects of psoralen derivatives on RAW264.7 cells via regulation of the NF-κB and MAPK signaling pathways[J]. International Journal of Molecular Sciences, 2022, 23(10): 5813. doi: 10.3390/ijms23105813
[37]	Silva P N S, Pereira H N S N, Santos L V N, Santos L C M M, Cavalcanti R J F, Aragão-Neto H C, Braga R M, Gadelha F A, Lopes M R, Sousa D P, Fonsêca D V. Umbelliferone presents orofacial antinociceptive and anti-inflammatory activity via reduction of TNF-α in mice[J]. Brazilian Journal of Biology, 2025, 85: e286667.
[38]	Xu G, Feng L L, Song P P, Xu F, Li A, Wang Y B, Shen Y, Wu X F, Luo Q, Wu X X, Sun Y, Wu X D, Xu Q. Isomeranzin suppresses inflammation by inhibiting M1 macrophage polarization through the NF-κB and ERK pathway[J]. International Immunopharmacology, 2016, 38: 175-185. doi: 10.1016/j.intimp.2016.05.027 pmid: 27285671
[39]	Ebrahimi S, Soukhtanloo M, Mostafavi-Pour Z. Anti-tumor effects of Auraptene through induction of apoptosis and oxidative stress in a mouse model of colorectal cancer[J]. Tissue and Cell, 2023, 81: 102004. doi: 10.1016/j.tice.2022.102004
[40]	Sunagawa Y, Kawaguchi S, Miyazaki Y, Katanasaka Y, Funamoto M, Shimizu K, Shimizu S, Hamabe-Horiike T, Kawase Y, Komiyama M, Mori K, Murakami A, Hasegawa K, Morimoto T. Auraptene, a Citrus peel-derived natural product, prevents myocardial infarction-induced heart failure by activating PPARα in rats[J]. Phytomedicine, 2022, 107: 154457. doi: 10.1016/j.phymed.2022.154457
[41]	Igase M, Okada Y, Ochi M, Igase K, Ochi H, Okuyama S, Furukawa Y, Ohyagi Y. Auraptene in the peels of Citrus kawachiensis (Kawachibankan) contributes to the preservation of cognitive function: A randomized, placebo-controlled, double-blind study in healthy volunteers[J]. The Journal of Prevention of Alzheimer’s Disease, 2018, 5(3): 197-201.
[42]	Zhan M, Yi Q, Yu L, Li Q K, Jiang M R, Wu D S, Jian M T, Cao H, Bin D H. Isopimpinellin: A promising treatment for colitis-related colorectal cancer that targets ALOX5-mediated macrophage polarization[J]. Phytotherapy Research, 2025, 39(11): 5249-5262. doi: 10.1002/ptr.v39.11
[43]	Hao Y F, Qin S W, Yang L, Jiang J G, Zhu W. Marmin from the blossoms of Citrus maxima (Burm.) Merr. exerts lipid-lowering effect via inducing 3T3-L1 preadipocyte apoptosis[J]. Journal of Functional Foods, 2021, 82: 104513. doi: 10.1016/j.jff.2021.104513
[44]	Han M J, Yu F, Li H H. Imperatorin ameliorates myocardial ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress-mediated apoptosis via the PI3K/AKT/Nrf2 pathway[J]. Journal of Cell Communication and Signaling, 2026, 20(2): e70084. doi: 10.1002/ccs3.v20.2
[45]	Liu B B, Deng X L, Jiang Q Q, Li G X, Zhang J L, Zhang N, Xin S L, Xu K S. Scoparone improves hepatic inflammation and autophagy in mice with nonalcoholic steatohepatitis by regulating the ROS/P38/Nrf2 axis and PI3K/AKT/mTOR pathway in macrophages[J]. Biomedicine & Pharmacotherapy, 2020, 125: 109895. doi: 10.1016/j.biopha.2020.109895
[46]	Lao Y J, Guo J Y, Fang J J, Geng R X, Li M J, Qin Y G, Wu J Y, Kang S G, Huang K L, Tong T. Beyond flavor: The versatile roles of eugenol in health and disease[J]. Food & Function, 2024, 15(21): 10567-10581.
[47]	Li T, Shi J, Wang L L, Qin X, Zhou R, Dong M, Ren F, Li X, Zhang Z H, Chen Y N, Liu Y H, Piao Y J, Shi Y, Xu S, Chen J, Li J. Thymol targeting interleukin 4 induced 1 expression reshapes the immune microenvironment to sensitize the immunotherapy in lung adenocarcinoma[J]. MedComm, 2023, 4(5): e355. doi: 10.1002/mco2.355 pmid: 37655051
[48]	Khodadadian R, Balali-Dehkordi S. A comprehensive review of the neurological effects of anethole[J]. IBRO Neuroscience Reports, 2025, 18: 50-56. doi: 10.1016/j.ibneur.2024.12.012 pmid: 39844944
[49]	Pragasam S J, Murunikkara V, Sabina E P, Rasool M. Ameliorative effect of p-coumaric acid, a common dietary phenol, on adjuvant- induced arthritis in rats[J]. Rheumatology International, 2013, 33(2): 325-334. doi: 10.1007/s00296-012-2394-4 pmid: 22447332
[50]	Kong C S, Jeong C H, Choi J S, Kim K J, Jeong J W. Antiangiogenic effects of p-coumaric acid in human endothelial cells[J]. Phytotherapy Research, 2013, 27(3): 317-323. doi: 10.1002/ptr.v27.3
[51]	Nayila I, Sharif S, Shahzad Lodhi M, Ullah R, Alotaibi A, Maqbool T, Hameed S. Formulation, characterization and evaluation of anti-breast cancer activity of 2-carene nanoemulsion; in silico, in vitro and in vivo study[J]. Arabian Journal of Chemistry, 2024, 17(9): 105937. doi: 10.1016/j.arabjc.2024.105937
[52]	Surendran S, Qassadi F, Surendran G, Lilley D, Heinrich M. Myrcene: What are the potential health benefits of this flavouring and aroma agent?[J]. Frontiers in Nutrition, 2021, 8: 699666. doi: 10.3389/fnut.2021.699666
[53]	Bonamin F, Moraes T M, dos Santos R C, Kushima H, Faria F M, Silva M A, Junior I V, Nogueira L, Bauab T M, Souza Brito A R M, da Rocha L R M, Hiruma-Lima C A. The effect of a minor constituent of essential oil from Citrus aurantium: The role of β-myrcene in preventing peptic ulcer disease[J]. Chemico-Biological Interactions, 2014, 212: 11-19. doi: 10.1016/j.cbi.2014.01.009 pmid: 24480520
[54]	Zhang L L, Yang Z Y, Fan G, Ren J N, Yin K J, Pan S Y. Antidepressant-like effect of Citrus sinensis (L.) Osbeck essential oil and its main component limonene on mice[J]. Journal of Agricultural and Food Chemistry, 2019, 67(50): 13817-13828. doi: 10.1021/acs.jafc.9b00650
[55]	Woo J, Yang H, Yoon M, Gadhe C G, Pae A N, Cho S, Lee C J. 3-carene, a phytoncide from pine tree has a sleep-enhancing effect by targeting the GABAA-benzodiazepine receptors[J]. Experimental Neurobiology, 2019, 28(5): 593-601. doi: 10.5607/en.2019.28.5.593
[56]	Liao P C, Yang T S, Chou J C, Chen J, Lee S C, Kuo Y H, Ho C L, Chao L K. Anti-inflammatory activity of neral and geranial isolated from fruits of Litsea cubeba Lour[J]. Journal of Functional Foods, 2015, 19: 248-258. doi: 10.1016/j.jff.2015.09.034
[57]	Sales A, de Oliveira Felipe L, Bicas J L. Production, properties, and applications of α-terpineol[J]. Food and Bioprocess Technology, 2020, 13(8): 1261-1279. doi: 10.1007/s11947-020-02461-6
[58]	Hosseini A, Pourheidar E, Rajabian A, Asadpour E, Hosseinzadeh H, Sadeghnia H R. Linalool attenuated ischemic injury in PC12 cells through inhibition of caspase-3 and caspase-9 during apoptosis[J]. Food Science & Nutrition, 2023, 11(1): 249-260. doi: 10.1002/fsn3.v11.1
[59]	Rekha K R, Selvakumar G P. Gene expression regulation of Bcl2, Bax and cytochrome-C by geraniol on chronic MPTP/probenecid induced C57BL/6 mice model of Parkinson’s disease[J]. Chemico-Biological Interactions, 2014, 217: 57-66. doi: 10.1016/j.cbi.2014.04.010
[60]	de Fazio L, Spisni E, Cavazza E, Strillacci A, Candela M, Centanni M, Ricci C, Rizzello F, Campieri M, Valerii M C. Dietary geraniol by oral or enema administration strongly reduces dysbiosis and systemic inflammation in dextran sulfate sodium-treated mice[J]. Frontiers in Pharmacology, 2016, 7: 38. doi: 10.3389/fphar.2016.00038 pmid: 26973525
[61]	何丽, 黄梅, 杨彩琴, 陈娜, 付凌云, 蒋朝晖, 王惠林, 沈祥春, 徐旖旎, 张彦燕. 松油烯-4-醇干预KLF4信号改善高糖诱导VSMCs氧化应激损伤的实验研究[J]. 中国药理学通报, 2020, 36(6): 839-844.
	He L, Huang M, Yang C Q, Chen N, Fu L Y, Jiang Z H, Wang H L, Shen X C, Xu Y N, Zhang Y Y. Effect of terpinen-4-ol ameliorating oxidative stress in VSMCs by down-regulation of KLF4[J]. Chinese Pharmacological Bulletin, 2020, 36(6): 839-844. (in Chinese)
[62]	Souto-Maior F N, de Carvalho F L, de Morais L C S L, Netto S M, de Sousa D P, de Almeida R N. Anxiolytic-like effects of inhaled linalool oxide in experimental mouse anxiety models[J]. Pharmacology Biochemistry and Behavior, 2011, 100(2): 259-263. doi: 10.1016/j.pbb.2011.08.029
[63]	Vinholes J, Rudnitskaya A, Gonçalves P, Martel F, Coimbra M A, Rocha S M. Hepatoprotection of sesquiterpenoids: A quantitative structure-activity relationship (QSAR) approach[J]. Food Chemistry, 2014, 146: 78-84. doi: 10.1016/j.foodchem.2013.09.039 pmid: 24176316
[64]	Klopell F C, Lemos M, Sousa J P, Comunello E, Maistro E L, Bastos J K, de Andrade S F. Nerolidol, an antiulcer constituent from the essential oil of Baccharis dracunculifolia DC (Asteraceae)[J]. Zeitschrift Fur Naturforschung C, Journal of Biosciences, 2007, 62(7/8): 537-542.
[65]	Fidyt K, Fiedorowicz A, Strządała L, Szumny A. β-caryophyllene and β-caryophyllene oxide: Natural compounds of anticancer and analgesic properties[J]. Cancer Medicine, 2016, 5(10): 3007-3017. doi: 10.1002/cam4.2016.5.issue-10
[66]	Rogerio A P, Andrade E L, Leite D F, Figueiredo C P, Calixto J B. Preventive and therapeutic anti-inflammatory properties of the sesquiterpene alpha-humulene in experimental airways allergic inflammation[J]. British Journal of Pharmacology, 2009, 158(4): 1074-1087. doi: 10.1111/j.1476-5381.2009.00177.x pmid: 19438512
[67]	Hui L M, Zhao G D, Zhao J J. δ-Cadinene inhibits the growth of ovarian cancer cells via caspase-dependent apoptosis and cell cycle arrest[J]. International Journal of Clinical and Experimental Pathology, 2015, 8(6): 6046-6056.
[68]	Delgado C, Mendez-Callejas G, Celis C. Caryophyllene oxide, the active compound isolated from leaves of Hymenaea courbaril L. (Fabaceae) with antiproliferative and apoptotic effects on PC-3 androgen-independent prostate cancer cell line [J]. Molecules, 2021, 26: 6142. doi: 10.3390/molecules26206142
[69]	Horiba T, Katsukawa M, Mita M, Sato R. Dietary obacunone supplementation stimulates muscle hypertrophy, and suppresses hyperglycemia and obesity through the TGR5 and PPARγ pathway[J]. Biochemical and Biophysical Research Communications, 2015, 463(4): 846-852. doi: 10.1016/j.bbrc.2015.06.022 pmid: 26051277
[70]	Chidambara Murthy K N, Jayaprakasha G K, Patil B S. Apoptosis mediated cytotoxicity of Citrus obacunone in human pancreatic cancer cells[J]. Toxicology in Vitro, 2011, 25(4): 859-867. doi: 10.1016/j.tiv.2011.02.006
[71]	Wang S C, Kuperman L L, Song Z H, Chen Y T, Liu K, Xia Z P, Xu Y G, Yu Q N. An overview of limonoid synthetic derivatives as promising bioactive molecules[J]. European Journal of Medicinal Chemistry, 2023, 259: 115704. doi: 10.1016/j.ejmech.2023.115704
[72]	Langeswaran K, Kumar S G, Perumal S, Revathy R, Balasubramaniam M P. Limonin-A Citrus limonoid, establish anticancer potential by stabilizing lipid peroxidation and antioxidant status against N- nitrosodiethylamine induced experimental hepatocellular carcinoma[J]. Biomedicine & Preventive Nutrition, 2013, 3: 165-171.
[73]	Mahmoud M F, Hamdan D I, Wink M, El-Shazly A M. Hepatoprotective effect of limonin, a natural limonoid from the seed of Citrus aurantium var. bigaradia, on D-galactosamine-induced liver injury in rats [J]. Naunyn-Schmiedeberg’s Archives of Pharmacology, 2014, 387(3): 251-261. doi: 10.1007/s00210-013-0937-1
[74]	Chen L, Fu B L, Liu J X, Wang C, Huang W J, Yuan D H, Qing C, Zhang Y, Hong H. Nomilin regulates depressive-like behaviors in mice via the ventral part of the lateral septum to bed nucleus of the stria Terminalis circuit[J]. CNS Neuroscience & Therapeutics, 2025, 31(11): e70647.
[75]	Fan S J, Yan Y X, Xia Y, Zhou Z Y, Luo L L, Zhu M N, Han Y L, Yao D Q, Zhang L J, Fang M L, Peng L N, Yu J, Liu Y, Gao X Y, Guan H D, Li H L, Wang C H, Wu X J, Zhu H H, Cao Y, et al. Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions[J]. Nature Communications, 2023, 14: 3368. doi: 10.1038/s41467-023-39118-9 pmid: 37291126
[76]	Subash-Babu P, Li D K, Alshatwi A A. In vitro cytotoxic potential of friedelin in human MCF-7 breast cancer cell: Regulate early expression of Cdkn2a and pRb1, neutralize mdm2-p53 amalgamation and functional stabilization of p53[J]. Experimental and Toxicologic Pathology, 2017, 69: 630-636. doi: 10.1016/j.etp.2017.05.011
[77]	Edwards C G, Walk A M, Thompson S V, Reeser G E, Dilger R N, Erdman J W Jr, Burd N A, Holscher H D, Khan N A. Dietary lutein plus Zeaxanthin and choline intake is interactively associated with cognitive flexibility in middle-adulthood in adults with overweight and obesity[J]. Nutritional Neuroscience, 2022, 25(7): 1437-1452. doi: 10.1080/1028415X.2020.1866867
[78]	Machida N, Kosehira M, Kitaichi N. Clinical effects of dietary supplementation of lutein with high bio-accessibility on macular pigment optical density and contrast sensitivity: A randomized double-blind placebo-controlled parallel-group comparison trial[J]. Nutrients, 2020, 12: 2966. doi: 10.3390/nu12102966
[79]	Lopresti A L, Smith S J, Drummond P D. The effects of lutein and zeaxanthin supplementation on cognitive function in adults with self-reported mild cognitive complaints: A randomized, double-blind, placebo-controlled study[J]. Frontiers in Nutrition, 2022, 9: 843512. doi: 10.3389/fnut.2022.843512
[80]	Zhao J R, Zhuang G J, Zhang J R. Neoxanthin: A promising medicinal and nutritional carotenoid[J]. Marine Drugs, 2025, 23(8): 317. doi: 10.3390/md23080317
[81]	Mapelli-Brahm P, Meléndez-Martínez A J. The colourless carotenoids phytoene and phytofluene: Sources, consumption, bioavailability and health effects[J]. Current Opinion in Food Science, 2021, 41: 201-209. doi: 10.1016/j.cofs.2021.04.013
[82]	Zhao H, Gu H H, Zhang H, Li J H, Zhao W E. PPARγ-dependent pathway in the growth-inhibitory effects of K562 cells by carotenoids in combination with rosiglitazone[J]. Biochimica et Biophysica Acta (BBA)-General Subjects, 2014, 1840(1): 545-555. doi: 10.1016/j.bbagen.2013.09.005
[83]	Stohs S J, Hartman M J. A review of the receptor binding and pharmacological effects of N-methyltyramine[J]. Phytotherapy Research, 2015, 29: 14-16. doi: 10.1002/ptr.5231 pmid: 25274429
[84]	Ni J N, Guo Y Y, Chang N W, Cheng D D, Yan M L, Jiang M, Bai G. Effect of N-methyltyramine on the regulation of adrenergic receptors via enzymatic epinephrine synthesis for the treatment of gastrointestinal disorders[J]. Biomedicine & Pharmacotherapy, 2019, 111: 1393-1398. doi: 10.1016/j.biopha.2018.12.145
[85]	Liu X, Shan X L, Chen H H, Li Z, Zhao P, Zhang C, Guo W, Xu M, Lu R. Stachydrine ameliorates cardiac fibrosis through inhibition of angiotensin II/transformation growth factor β1 fibrogenic axis[J]. Frontiers in Pharmacology, 2019, 10: 538. doi: 10.3389/fphar.2019.00538 pmid: 31178725
[86]	Ding W Q, Liu B L, Vaught J L, Palmiter R D, Lind S E. Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells[J]. Molecular Cancer Therapeutics, 2006, 5(7): 1864-1872. doi: 10.1158/1535-7163.MCT-06-0067
[87]	Shin E J, Choi H K, Sung M J, Park J H, Chung M Y, Chung S, Hwang J T. Anti-tumour effects of beta-sitosterol are mediated by AMPK/PTEN/HSP90 axis in AGS human gastric adenocarcinoma cells and xenograft mouse models[J]. Biochemical Pharmacology, 2018, 152: 60-70. doi: S0006-2952(18)30107-2 pmid: 29559312
[88]	Ponnulakshmi R, Shyamaladevi B, Vijayalakshmi P, Selvaraj J. In silico and in vivo analysis to identify the antidiabetic activity of beta sitosterol in adipose tissue of high fat diet and sucrose induced type-2 diabetic experimental rats[J]. Toxicology Mechanisms and Methods, 2019, 29(4): 276-290. doi: 10.1080/15376516.2018.1545815 pmid: 30461321
[89]	Zomkowski A D, Santos A R, Rodrigues A L. Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice[J]. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2006, 30(8): 1419-1425. doi: 10.1016/j.pnpbp.2006.05.016
[90]	Chen J J, Yuan Z Y, Zhang H P, Li W Y, Shi M Y, Peng Z X, Li M Y, Tian J, Deng X X, Cheng Y J, Deng C H, Xie Z Z, Zeng J W, Yao J L, Xu J. Cit1, 2RhaT and two novel CitdGlcTs participate in flavor- related flavonoid metabolism during Citrus fruit development[J]. Journal of Experimental Botany, 2019, 70(10): 2759-2771. doi: 10.1093/jxb/erz081
[91]	Li W Y, Li G, Yuan Z Y, Li M Y, Deng X X, Tan M L, Ma Y H, Chen J J, Xu J. Illustration of the variation in the content of flavanone rutinosides in various Citrus germplasms from genetic and enzymatic perspectives[J]. Horticulture Research, 2022, 9: uhab017.
[92]	Wu G A, Terol J, Ibanez V, López-García A, Pérez-Román E, Borredá C, Domingo C, Tadeo F R, Carbonell-Caballero J, Alonso R, Curk F, Du D L, Ollitrault P, Roose M L, Dopazo J, Gmitter F G, Rokhsar D S, Talon M. Genomics of the origin and evolution of Citrus[J]. Nature, 2018, 554(7692): 311-316. doi: 10.1038/nature25447
[93]	Liu S J, Xu Y T, Yang K, Huang Y, Lu Z H, Chen S L, Gao X, Xiao G A, Chen P, Zeng X L, Wang L, Zheng W K, Liu Z S, Liao G L, He F, Liu J J, Wan P F, Ding F, Ye J L, Jiao W B, et al. Origin and de novo domestication of sweet orange[J]. Nature Genetics, 2025, 57(3): 754-762. doi: 10.1038/s41588-025-02122-4
[94]	徐娟, 吴东轩, 余红星, 陈嘉景, 尹守铮. 一种基于InDel分子标记的枳实基原植物鉴别方法及专用引物组合: CN202511123834.6[P]. 2026-04-21.
	Xu J, Wu D X, Yu H X, Chen J J, Yin S Z. A method for identifying source plants of Aurantii Fructus Immaturus based on InDel molecular markers and specific primer composition: CNZL202511123834.6[P]. 2026-04-21. (in Chinese)
[95]	Peng Z X, Song L Z, Chen M H, Liu Z Y, Yuan Z Y, Wen H, Zhang H P, Huang Y, Peng Z W, Yang H B, Li G, Zhang H X, Hu Z H, Li W Y, Wang X, Larkin R M, Deng X X, Xu Q, Chen J J, Xu J. Neofunctionalization of an OMT cluster dominates polymethoxyflavone biosynthesis associated with the domestication of Citrus[J]. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(14): e2321615121.
[96]	Tang Y R, Fang K, Ding A, Chen O, Zhou K, Xi W P. Detecting the coumarin profile in Citrus fruit by a large-scale assessment of cultivated and wild accessions[J]. Food Chemistry, 2026, 500: 147426. doi: 10.1016/j.foodchem.2025.147426
[97]	Munakata R, Olry A, Takemura T, Tatsumi K, Ichino T, Villard C, Kageyama J, Kurata T, Nakayasu M, Jacob F, Koeduka T, Yamamoto H, Moriyoshi E, Matsukawa T, Grosjean J, Krieger C, Sugiyama A, Mizutani M, Bourgaud F, Hehn A, et al. Parallel evolution of UbiA superfamily proteins into aromatic O-prenyltransferases in plants[J]. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118(17): e2022294118.
[98]	Wen H, Liu Y, Hu Z H, Wu D X, Shui L L, Zhao Z P, Li G, Chen G X, Chen J J, Liu X, Chen X L, Deng C H, Zhang H P, He X X, Zhang X X, Deng X X, Zhu A D, Xu J. A solo-LTR insertion in the CreTPS3a promoter enhances γ-terpinene biosynthesis and affects consumer preference for tangerine-like aroma in Citrus fruits[J]. Molecular Plant, 2026, 19(2): 242-261. doi: 10.1016/j.molp.2025.09.007
[99]	张睿胤, 成凤, 郑亚杰, 陈鹏, 陆英, 袁建华, 李先信, 唐其. 基于HS-SPME-GC-MS法测定酸橙不同时期及不同部位的挥发性成分[J]. 天然产物研究与开发, 2022, 34(5): 790-799.
	Zhang R Y, Cheng F, Zheng Y J, Chen P, Lu Y, Yuan J H, Li X X, Tang Q. Determination of volatile components in different periods and parts of Citrus aurantium L. based on HS-SPME-GC-MS [J]. Natural Product Research and Development, 2022, 34(5): 790-799. (in Chinese)
[100]	Yuan Z Y, Li G, Zhang H X, Peng Z X, Ding W Y, Wen H, Zhou H X, Zeng J W, Chen J J, Xu J. Four novel Cit7GlcTs functional in flavonoid 7-O-glucoside biosynthesis are vital to flavonoid biosynthesis shunting in Citrus[J]. Horticulture Research, 2024, 11(6): uhae098.
[101]	Huang S J, Dong T T, Xiong B, Qiu X, Sun G C, Liao L, Fan N N, Wang X, Deng H H, He S Y, Hu Y S, Wang Z H. Variation in the content and composition of limonoids in fruits of four pomelo varieties during fruit development: The natural debittering process in pomelo fruits[J]. Journal of Food Composition and Analysis, 2021, 100: 103928. doi: 10.1016/j.jfca.2021.103928
[102]	李雪, 蔡中虎, 高俊燕, 陈嘉景, 刘园, 徐娟. 云南巍山不同采收季广东香水柠檬(Citrus medica)挥发性物质差异分析[J]. 园艺学报, 2025, 52(9): 2439-2452. doi: 10.16420/j.issn.0513-353x.2024-0943
	Li X, Cai Z H, Gao J Y, Chen J J, Liu Y, Xu J. Differences in volatile compounds of Citrus medica ‘Guangdong Xiangshui’ fruits in different harvesting seasons from Weishan of Yunnan Province[J]. Acta Horticulturae Sinica, 2025, 52(9): 2439-2452. (in Chinese)
[103]	Shang N, Tong P P, Ye P, Su J M, Bai M, Wu H. Crc1, 6RhaT is involved in the synthesis of hesperidin of the main bioactive substance in the Citrus reticulata ‘Chachi’ fruit[J]. Horticultural Plant Journal, 2024, 10(6): 1321-1335. doi: 10.1016/j.hpj.2022.10.012
[104]	李正红, 陈海芳, 骆利平, 杨标, 魏莹, 袁金斌, 龚千峰, 杨武亮. 江枳壳不同采收期活性成分HPLC含量测定[J]. 中药材, 2013, 36(1): 28-31.
	Li Z H, Chen H F, Luo L P, Yang B, Wei Y, Yuan J B, Gong Q F, Yang W L. Determination of the active constituents in aurantii fructus from Jiangxi Province at different harvest time by HPLC[J]. Journal of Chinese Medicinal Materials, 2013, 36(1): 28-31. (in Chinese)
[105]	田静, 庞一波, 陈嘉景, 袁子彧, 曾继吾, 徐娟. 化州柚种质资源的SSR分析及其果实不同发育期柚皮苷含量变化[J]. 华中农业大学学报, 2019, 38(5): 64-70.
	Tian J, Pang Y B, Chen J J, Yuan Z Y, Zeng J W, Xu J. SSR analyses of germplasm resources and changes of naringin content at different developmental stages of Citrus grandis ‘Tomentosa’ fruit[J]. Journal of Huazhong Agricultural University, 2019, 38(5): 64-70. (in Chinese)
[106]	潘媛, 陈大霞, 李隆云. 川佛手不同发育时期的比较转录组学分析[J]. 中国中药杂志, 2020, 45(21): 5169-5176.
	Pan Y, Chen D X, Li L Y. Comparative transcriptomics analysis of Citrus medica var. sarcodactylis at different developmental stages [J]. China Journal of Chinese Materia Medica, 2020, 45(21): 5169-5176. (in Chinese)
[107]	Li Y Q, Kong D X, Fu Y, Sussman M R, Wu H. The effect of developmental and environmental factors on secondary metabolites in medicinal plants[J]. Plant Physiology and Biochemistry, 2020, 148: 80-89. doi: S0981-9428(20)30006-1 pmid: 31951944
[108]	Su J M, Wang Y Y, Bai M, Peng T H, Li H S, Xu H J, Guo G F, Bai H Y, Rong N, Sahu S K, He H J, Liang X X, Jin C Z, Liu W, Strube M L, Gram L, Li Y T, Wang E T, Liu H, Wu H. Soil conditions and the plant microbiome boost the accumulation of monoterpenes in the fruit of Citrus reticulata ‘Chachi’[J]. Microbiome, 2023, 11: 61. doi: 10.1186/s40168-023-01504-2
[109]	林励, 欧剑锋, 廖观荣, 邱金裕, 蔡岳文, 肖凤霞, 李向明. 化橘红道地性的初步研究[J]. 广州中医药大学学报, 2010, 27(2): 163-170.
	Lin L, Ou J F, Liao G R, Qiu J Y, Cai Y W, Xiao F X, Li X M. Studies on genuineness of exocarpium citri grandis[J]. Journal of Guangzhou University of Traditional Chinese Medicine, 2010, 27(2): 163-170. (in Chinese)
[110]	陈欢, 高萌, 罗小泉, 陈海芳, 袁金斌, 杨武亮. 不同产地枳壳药材中12种有效成分的主成分分析和判别分析[J]. 中草药, 2019, 50(14): 3433-3437.
	Chen H, Gao M, Luo X Q, Chen H F, Yuan J B, Yang W L. Principal component analysis and discriminant analysis of 12 effective chemical constituents in Aurantii Fructus from different areas[J]. Chinese Traditional and Herbal Drugs, 2019, 50(14): 3433-3437. (in Chinese)
[111]	Bedada S K, Neerati P. Modulation of CYP3A enzyme activity by diosmin and its consequence on carbamazepine pharmacokinetics in rats[J]. Naunyn-Schmiedeberg’s Archives of Pharmacology, 2018, 391(2): 115-121. doi: 10.1007/s00210-017-1439-3
[112]	Xu J, Ma L L, Jiang D, Zhu S P, Yan F H, Xie Y X, Xie Z Z, Guo W W, Deng X X. Content evaluation of 4 furanocoumarin monomers in various Citrus germplasms[J]. Food Chemistry, 2015, 187: 75-81. doi: 10.1016/j.foodchem.2015.04.007
[113]	钟永翠, 巩珺, 徐家能, 杨立伟, 梁生旺. 基于3种黄酮类化合物含量比值鉴别广陈皮道地性[J]. 药物分析杂志, 2017, 37(1): 20-29. doi: 10.16155/j.0254-1793.2017.01.03
	Zhong Y C, Gong J, Xu J N, Yang L W, Liang S W. Identification of Citrus reticulata ‘Chachi’ by the proportion of three flavonoids[J]. Chinese Journal of Pharmaceutical Analysis, 2017, 37(1): 20-29. (in Chinese)
[114]	周晗昕, 刘园, 袁子彧, 曾继吾, 肖雪, 陈嘉景, 朱安婷, 徐娟. 多组学联合解析干制和陈化对广陈皮代谢品质的影响[J]. 中国科学: 生命科学, 2025, 55(6): 1288-1305.
	Zhou H X, Liu Y, Yuan Z Y, Zeng J W, Xiao X, Chen J J, Zhu A T, Xu J. Multi-omics joint analysis of the effects of drying and aging on the metabolic quality of Guangchenpi[J]. Scientia Sinica (Vitae), 2025, 55(6): 1288-1305. (in Chinese)
[115]	何中燕. 橘核质量及柠檬苦素类似物纯化工艺的研究[D]. 成都: 成都中医药大学, 2012.
	He Z Y. Study on quality of tangerine seed and purification of limonoids[D]. Chengdu: Chengdu University of Traditional Chinese Medicine, 2012. (in Chinese)
[116]	于芷芩, 张良琦, 蔡煜涵, 吴月峰, 袁筱, 贺福元, 周晋. “同源异效”中药枳实和枳壳的研究进展[J]. 中国中药杂志, 2024, 49(19): 5135-5146.
	Yu Z Q, Zhang L Q, Cai Y H, Wu Y F, Yuan X, He F Y, Zhou J. Research progress on “homologous different effects” of Aurantii Fructus Immaturus and Aurantii Fructus[J]. China Journal of Chinese Materia Medica, 2024, 49(19): 5135-5146. (in Chinese)
[117]	严辉, 高明亮, 查玉玲, 陈静梅, 濮宗进, 郭盛, 周桂生, 陈佩东, 詹志来. 香橼化学成分和药理作用研究进展及其质量标志物预测分析[J]. 中国现代应用药学, 2022, 39(7): 976-988.
	Yan H, Gao M L, Zha Y L, Chen J M, Pu Z J, Guo S, Zhou G S, Chen P D, Zhan Z L. Research progress on chemical components and pharmacological effects of citri fructus and predictive analysis on its quality marker[J]. Chinese Journal of Modern Applied Pharmacy, 2022, 39(7): 976-988. (in Chinese)
[118]	刘心语. 佛手质量标志物的研究[D]. 成都: 西南交通大学, 2021.
	Liu X Y. Study on quality markers of Fructus Citri Sarcodactylis[D]. Chengdu: Southwest Jiaotong University, 2021. (in Chinese)
[119]	Lado J, Alós E, Manzi M, Cronje P J R, Gómez-Cadenas A, Rodrigo M J, Zacarías L. Light regulation of carotenoid biosynthesis in the peel of Mandarin and sweet orange fruits[J]. Frontiers in Plant Science, 2019, 10: 1288. doi: 10.3389/fpls.2019.01288 pmid: 31681382
[120]	Wen J W, Wang Y Y, Lu X, Pan H M, Jin D, Wen J L, Jin C Z, Sahu S K, Su J M, Luo X Y, Jin X H, Zhao J, Wu H, Liu E H, Liu H. An integrated multi-omics approach reveals polymethoxylated flavonoid biosynthesis in Citrus reticulata cv. Chachiensis[J]. Nature Communications, 2024, 15: 3991. doi: 10.1038/s41467-024-48235-y
[121]	Liu S J, Wang L Y, Zhang X, Sun L F, Ke F Z, Huang Y, Song L Z, Ye H P, Xu J G, Xu Y T, Wang X, Deng X X, Liu G P, Xu Q. Genomic origin of Citrus reticulata “Unshiu”[J]. Horticulture Research, 2025, 12(5): uhaf015.
[122]	Zheng W K, Zhang W, Liu D H, Yin M Q, Wang X, Wang S C, Shen S Q, Liu S J, Huang Y, Li X X, Zhao Q, Yan L, Xu Y T, Yu S Q, Hu B, Yuan T, Mei Z N, Guo L P, Luo J, Deng X X, et al. Evolution-guided multiomics provide insights into the strengthening of bioactive flavone biosynthesis in medicinal pummelo[J]. Plant Biotechnology Journal, 2023, 21(8): 1577-1589. doi: 10.1111/pbi.v21.8
[123]	Feng D, Liu S J, Chen M J, Wang S H, Xu M, Liu C L, Huang W K, Wang M, Xie P, Chai L J, Ye J L, Xu Q, Zeng X L, Xu J, Deng X X. Volatile content and genetic variation of citron in Tibet and Yunnan[J]. Plant Physiology, 2024, 197(1): kiae634.
[124]	Liu Y, Wen H, Hu Z H, Liu X, Chen Q H, Wen T L, Liang Y N, Hu Y, Zeng J W, Chen J J, Xu J. CreSAMT1 is mainly responsible for the biosynthesis of characteristic aroma compound dimethyl anthranilate in Citrus reticulata ‘Chachiensis’[J]. Horticulture Research, 2026, 13(3): uhaf331.
[125]	Liu Y, Wen H, Kong J T, Hu Z H, Hu Y, Zeng J W, Chen X L, Zhang H Y, Chen J J, Xu J. Flavor characterization of Citri Reticulatae Pericarpium (Citrus reticulata ‘Chachiensis’) with different aging years via sensory and metabolomic approaches[J]. Food Chemistry, 2024, 443: 138616. doi: 10.1016/j.foodchem.2024.138616
[126]	Liu Y, Wang X Q, Yan Z Y, Wen H, Chen Q H, Hu Y, Huang H J, Liu C L, Zeng J W, Chen J J, Xu J. Glycosidically bound volatiles profiling reveals a new approach to effectively gauge aging years of Guangchenpi (Citrus reticulata ‘Chachiensis’) [J]. Horticulture Advances, 2025, 3(1): 25. doi: 10.1007/s44281-025-00079-2
[127]	Chen J J, Li G, Zhang H P, Yuan Z Y, Li W Y, Peng Z X, Shi M Y, Ding W Y, Zhang H X, Cheng Y J, Yao J L, Xu J. Primary bitter taste of Citrus is linked to a functional allele of the 1, 2-rhamnosyltransferase gene originating from Citrus grandis[J]. Journal of Agricultural and Food Chemistry, 2021, 69(34): 9869-9882. doi: 10.1021/acs.jafc.1c01211
[128]	Liang X, Wang Y, Shen W X, Liao B, Liu X J, Yang Z M, Chen J B, Zhao C N, Liao Z K, Cao J P, Wang P, Wang P, Ke F Z, Xu J G, Lin Q, Xi W P, Wang L S, Xu J, Zhao X C, Sun C D. Genomic and metabolomic insights into the selection and differentiation of bioactive compounds in Citrus[J]. Molecular Plant, 2024, 17(11): 1753-1772. doi: 10.1016/j.molp.2024.10.009
[129]	徐娟, 刘园, 张海朋, 李莉, 蒋友武, 张红艳. 一种茶枝柑InDel分子标记及其特异引物在广陈皮真伪鉴定上的应用: ZL202110779936.9 [P]. 2022-04-08.
	XU J, LIU Y, ZHANG H P, LI L, JIANG Y W, ZHANG H Y. Application of an InDel molecular marker and its specific primer for Citrus reticulata ‘Chachiensis’ in the authenticity identification of Citri Reticulatae Pericarpium: CNZL202110779936.9[P]. 2022-04-08. (in Chinese)
[130]	徐娟, 莫小琴, 陈嘉景, 李古, 袁子彧, 曾继吾, 蒋友武. 用于区分毛橘红和光橘红原料植物的分子标记及其应用: CN201911001504.4[P]. 2021-06-11.
	Xu J, Mo X Q, Chen J J, Li G, Yuan Z Y, Zeng J W, Jiang Y W. Molecular marker for distinguishing raw material plants of Citrus grandis ‘Tomentosa’ and Citrus grandis ‘Shatianyu’ and its application: CNZL201911001504.4[P]. 2021-06-11. (in Chinese)
[131]	陈嘉景, 吴东轩, 温欢, 刘园, 赵志鹏, 徐娟. 一种用于鉴定建柑的分子标记及其应用: CN202510349038.8[P]. 2026-04-17.
	Chen J J, Wu D X, Wen H, Liu Y, Zhao Z P, Xu J. A molecular marker for identifying Jian Gan and its application: CNZL202510349038.8[P]. 2026-04-17. (in Chinese)
[132]	Chen P, Liu J B, Tang Q, Zhou T, Guo L X, Xu Y Y, Chai L J, Xu Q, Deng Z N, Li X X. Genetic identification of medicinal Citrus cultivar ‘Local Juhong’ using molecular markers and genomics[J]. Genes, 2024, 15(6): 719. doi: 10.3390/genes15060719
[133]	康婧博, 温欢, 吴群, 熬义俊, 陈嘉景, 刘园, 徐娟. 七种香橙种质挥发性物质比较分析[J]. 园艺学报, 2026, 53(1): 25-40. doi: 10.16420/j.issn.0513-353x.2025-0081
	Kang J B, Wen H, Wu Q, Ao Y J, Chen J J, Liu Y, Xu J. Comparative analysis of volatile compounds in seven Citrus junos germplasms[J]. Acta Horticulturae Sinica, 2026, 53(1): 25-40. (in Chinese)
[134]	Liu J L, Zeng D Y, Hu B C, Wang W P, Hu S M, Li H N, Zhao X Y, Zhao H T, Dai C H, Lu W H. Huajuhong (Citri grandis Exocarpium): Phytochemistry, bioactivities, functional food development, and artificial intelligence-driven strategies[J]. Trends in Food Science & Technology, 2026, 175: 105894.

Metrics

Viewed

Full text

Abstract

Cited

Shared

Discussed

Comments

Recommended 0

No Suggested Reading articles found!

Research Progress and Prospect of Medicinal Citrus Application

RichHTML

PDF

Abstract

Cite this article

share this article

Figures/Tables 7

References 134

Related Articles 15

Metrics

Comments

Recommended 0

[1]	WANG XiaoWei, DU FoLi, YAN HongCai, LANG ZhengDong, DANG ZhiJuan, LI BaoChun, WANG JunCheng, MA XiaoLe, WANG HuaJun, ZHANG Hong, YAO LiRong. Evaluation of Drought Resistance of 396 Spring Wheat Varieties at Grain Filling Stage and Maturity Stage [J]. Scientia Agricultura Sinica, 2026, 59(8): 1608-1621.
[2]	CUI JieHao, ZHANG Meng, WANG Qin, YU JiaYan, LIN Kun, LI ShangZe, LAN Heng, GENG YanQiu, ZHANG Qiang, GUO LiYing, SHAO XiWen. Evaluation of Lodging Resistance and Its Physiological Mechanisms in Japonica Rice Resources [J]. Scientia Agricultura Sinica, 2026, 59(7): 1420-1438.
[3]	HAO Kun, CHEN HongDe, ZHANG Wei, ZHONG Yun, DANG MeiRong, ZHU ShiJiang, HUANG ZhiKun, JIN Ying. Comprehensive Evaluation of Water-Nitrogen Management Under Surge-Root Irrigation Based on Citrus Yield, Quality, and Water- Nitrogen Use Efficiency [J]. Scientia Agricultura Sinica, 2026, 59(4): 862-873.
[4]	LIU DanDan, DING WenTao, CHENG QiCan, ZHANG Yu, XING AiShuang, GUO XiangLong, XING Han, GUO Na, ZHAO JinMing. Genetic Diversity and Genome-Wide Association Study of Amino Acid Content in Soybean Seeds at the R6 Stage [J]. Scientia Agricultura Sinica, 2026, 59(20): 4461-4475.
[5]	SU WanLong, REN HaiYan, XUE XiaoFang, SHI MeiJuan, LIU Li, ZHAO AiLing, LI Yi, WANG YongKang. Comprehensive Evaluation of Jujube Fruit Quality Based on Sensory, Texture, and Physicochemical Analysis [J]. Scientia Agricultura Sinica, 2026, 59(18): 4135-4148.
[6]	DING Qian, HE LiLian, QIAN ZhenFeng, WU QiBin, ZHAO ChangZu, LIN PeiXia, NONG WeiYou, WANG YuJie, ZHANG YuanYuan, QUE YouXiong, LI FuSheng. Comprehensive Evaluation of Defoliation Ability of Different Sugarcane Varieties/Lines and Analysis of Cell Morphology and Physiological Differences in Leaf Sheath Abscission Zone [J]. Scientia Agricultura Sinica, 2026, 59(15): 3315-3327.
[7]	XIE YongXiang, PAN YiMin, HUANG Rui, QIN HuiBin, HOU Sen, HE Qiang, LING Liang, MU ZhiXin, WANG HaiGang. Identification and Comprehensive Evaluation of the Barren-Tolerant Germplasm Resources of Foxtail Millet in Shanxi [J]. Scientia Agricultura Sinica, 2026, 59(11): 2325-2339.
[8]	ZHANG YueQing, ZHANG YuTing, XUE ChenFei, HAN QinYu, HE YiRong, XU ZiJuan, FAN XiuMei, WANG JunE, LUO Dan, FENG Xue, SUN Sheng. Genetic Diversity Analysis and Comprehensive Evaluation of Phenotypic Traits in 364 Cherry Tomato Germplasm Resources [J]. Scientia Agricultura Sinica, 2026, 59(11): 2468-2483.
[9]	CHEN TianXiao, CAO Rong, SONG QianNan, HU LiangLiang, WANG SuHua, WANG LiXia, CHENG XuZhen, CHEN HongLin. Comprehensive Evaluation of Salt Tolerance at the Seedling Stage and Screening of Tolerant Germplasm in Adzuki Bean (Vigna angularis) [J]. Scientia Agricultura Sinica, 2025, 58(21): 4317-4332.
[10]	TANG GuiMei, LI WeiDong, ZHOU YuXia, KONG YouHan, XIAO XiaoLing, PENG YingShu, ZHANG Li, FU HongYan, LIU Yang, HUANG GuoLin. Genetic Diversity Analysis of Cymbidium faberi Germplasm Resources Based on Phenotypic Traits [J]. Scientia Agricultura Sinica, 2025, 58(2): 339-354.
[11]	ZHAO TianTian, YUAN JianLong, ZHUO FengQi, TANG ZhenSan, XU Jie, ZHANG Feng. Comprehensive Evaluation of Potato Flour Quality and Variety Screening [J]. Scientia Agricultura Sinica, 2025, 58(13): 2522-2537.
[12]	QIAO ZhengYan, YU Miao, TANG YuJie, SHI GuiShan, LIU XinYu, LIU XiaoHan, WANG XinDing, LI Yang, WANG Nai, CHEN BingRu. Comprehensive Evaluation for Soda Salinity and Alkalinity in Sorghum Seedling Stage and Selection of Indicators [J]. Scientia Agricultura Sinica, 2025, 58(1): 30-42.
[13]	LI PeiSong, LU YongDi, GUO Yu, ZHANG QiPeng, LIU TaoFen, WANG TianHe, YANG MingFeng, XIANG Dao, TIAN JingShan, ZHANG WangFeng. The Regional Distribution of Raw Cotton Quality in Xinjiang Based on Notarized Inspection Data for Cotton [J]. Scientia Agricultura Sinica, 2025, 58(1): 58-74.
[14]	GUO Lei, HUANG ChenYan, SONG HongFeng, SHEN ZhiJun, ZHANG BinBin, MA RuiJuan, SUN Meng, HE Xin, YU MingLiang. Screening, Compounding and Safety Evaluation of Herbicides Suitable for Peach Nursery [J]. Scientia Agricultura Sinica, 2024, 57(9): 1734-1747.
[15]	WU YuZhen, HUANG LongYu, ZHOU DaYun, HUANG YiWen, FU ShouYang, PENG Jun, KUANG Meng. Construction of SSR Fingerprint Library and Comprehensive Evaluation for Approved Cotton Varieties in China [J]. Scientia Agricultura Sinica, 2024, 57(8): 1430-1443.