Scientia Agricultura Sinica ›› 2009, Vol. 42 ›› Issue (6): 2164-2171 .doi: 10.3864/j.issn.0578-1752.2009.06.037

• VETERINARY SCIENCE • Previous Articles     Next Articles

Immune Enhancement Effect of Mixed Herbal Extracts in Chicks Immnunosuppressed by Reticuloendotheliosis Virus Infection

LIU Feng-xiang, CUI Zhi-zhong, GUO Hui-jun   

  1. （山东农业大学动物科技学院）
  • Received:2008-03-18 Revised:2008-10-17 Online:2009-06-10 Published:2009-06-10
  • Contact: CUI Zhi-zhong

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Abstract:

【Objective】 To research immune enhancement effect of mixed herbal extracrs in chicks immunosuppressed by reticuloendotheliosis virus infection and establish an experiment model for determination of immune enhancing effects of some herbs.【Method】 Immune enhancement of herbal extracts was determined in clinical health chicks and chicks with immunosuppression induced by reticuloendotheliosis virus (REV) infection. 【Result】 Hemagglutination inhibition (HI) antibody titers against Newcastle disease virus (NDV) and H5 avian influenza virus (H5-AIV) after vaccination were not influenced by supplement with the extract of mixed herbs, Radix Astragali, Radix Codonopis, Herba Epimedii and Radix Glycyrrizae in drinking water in clinical health chicks. In chicks immunosuppressed by reticuloendotheliosis virus (REV) infection, however, supplement of the same herbal extract in drinking water significantly increased HI antibody titers to NDV and H5-AIV when compared to the immunosuppressed control group (P＜0.01). 【Conclusion】 It is concluded that chicks with REV-induced immunosuppression could be used as an experiment model for determination of immune enhancing effects of some herbs.

Key words: Key words: herbal extraction, immunosuppression, REV, humoral immunity

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