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Journal of Integrative Agriculture  2024, Vol. 23 Issue (5): 1447-1453    DOI: 10.1016/j.jia.2024.03.044
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Control of highly pathogenic avian influenza through vaccination

Xianying Zeng, Jianzhong Shi, Hualan Chen#

State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, China
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Abstract  

The stamping-out strategy has been used to control highly pathogenic avian influenza viruses in many countries, driven by the belief that vaccination would not be successful against such viruses and fears that avian influenza virus in vaccinated birds would evolve more rapidly and pose a greater risk to humans.  In this review, we summarize the successes in controlling highly pathogenic avian influenza in China and make suggestions regarding the requirements for vaccine selection and effectiveness.  In addition, we present evidence that vaccination of poultry not only eliminates human infection with avian influenza virus, but also significantly reduces and abolishes some harmful characteristics of avian influenza virus.

Keywords:  avian influenza       control        highly pathogenic        vaccination   
Received: 02 February 2024   Accepted: 27 February 2024
Fund: This work was supported by the National Key Research and Development Program of China (2021YFD1800200 and 2021YFC2301700).
About author:  Xianying Zeng, E-mail: zengxianying@caas.cn; #Correspondence Hualan Chen, Tel: +86-451-51997168, Fax: +86-451-51997166, E-mail: chenhualan@caas.cn

Cite this article: 

Xianying Zeng, Jianzhong Shi, Hualan Chen. 2024.

Control of highly pathogenic avian influenza through vaccination . Journal of Integrative Agriculture, 23(5): 1447-1453.

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