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| Antioxidant Effects of Oats Avenanthramides on Human Serum |
| Institute of Comprehensive Utilization of Agricultural Products, Shanxi Academy of Agriculture Sciences |
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摘要 The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study.Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon.Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides)groups, the levels of serum superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantlyincreased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%.The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1,28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treatwas increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramidespossessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to preventhyperlipemic and angiocardiopathy.
Abstract The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study.Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon.Plasma lipid peroxides and antioxidant status were measured. For 8 capsules (containing 3.12 mg avenanthramides)groups, the levels of serum superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantlyincreased by 8.4 and 17.9%, respectively (P<0.05), and malondialdehyde (MDA) level significantly decreased by 28.1%.The total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1,28.1, and 15.1%, respectively (P<0.05). The high density blood lipoprotein cholesterol (HDL-C) levels in the same treatwas increased by 13.2%. Based on our research, it can be concluded that oats extract containing avenanthramidespossessed a high antioxidative activity on humans. It indicated that oat avenanthramides could be used to preventhyperlipemic and angiocardiopathy.
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Received: 01 October 2010
Accepted: 16 August 2011
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Corresponding Authors:
Correspondence REN Gui-xing, Professor, Tel: +86-10-62115596, Fax: +86-10-62156596, E-mail: renguixing@caas.net.cn
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Cite this article:
LIU Sen, YANG Nan, HOU Zhao-hua, YAO Yang, Lü Li, ZHOU Xian-rong, REN Gui-xing.
2011.
Antioxidant Effects of Oats Avenanthramides on Human Serum. Journal of Integrative Agriculture, 10(8): 1301-1305.
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