关键词: 黑米皮提取物, 降血脂, 抗氧化, 花色苷, 脂肪酸

Abstract: To investigate the effect of black rice pericarp extracts on oxidative stress and the serum lipid profile and the effective components for this effect. 【METHOD】Male adult SD rats (60) were used in the present study. They were divided into five groups, which were normal control group, hyperlipidemia model group and 3 experimental groups which were given different doses of black rice pericarp extracts (5％、10%、20% in water,w/v, 1mL/100 body weight). After 8 weeks, the serum lipid profile, the total the activity of antioxidative enzyme and the content of malondialdehyde in serum and liver were determined in different groups of rats. 【RESULTS】Feeding black rice pericarp extracts to rats significantly reduced the levels of serum lipids and the titer of the antibody to oxidized low density lipoprotein (P<0.05). Serum and liver malondialdehyde content decreased in rats delivered black rice pericarp extracts, however, total antioxidation capacity and the activity of antioxidative enzyme increased. Analyzing the components revealed that there were 43.43% of anthocyanin and 15.7% of nonsaturated fatty acids, most of which were oleic acid and linoleic acid. 【CONCLUSION】Black rice pericarp extracts showed antioxidative and hypolipidemic effects, which might resulted from the anthocyanins and unsaturated fatty acid containing in extracts.

Key words: Black rice pericarp extract, Hypolipidemic, Antioxidation, Anthocyanin, Fatty acid