Scientia Agricultura Sinica ›› 2005, Vol. 38 ›› Issue (03): 596-600 .doi: 10.3864/j.issn.0578-1752.at-2004-2070

• ANIMAL SCIENCE·VETERINARY SCIENCERE·SOURCE INSECT • Previous Articles     Next Articles

Study on the Protective Efficiency of the Genetic Subunit Bacterin Against Porcine Contagious Pleuropneumonia

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  1. 华中农业大学动物医学院
  • Received:2004-02-02 Revised:2004-12-16 Online:2005-03-10 Published:2005-03-10

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Abstract: The efficacy of a new genetic subunit bacterin containing recombinant Apx toxins and serovar 7 of Actinobacillus pleuropneumoniae was determined. Weaned piglets were vaccinated twice intramuscularly with the new genetic subunit bacterin or commerical trivalent formalin-inactivated A. pleuropneumoniae. The antibody of each antigen was detected each week after first immunization. Piglets were challenged by percutaneous intratracheal injection with serovar 1. The protective efficacy of immunization was evaluated by clinical, bacteriological, serological and post-mortem examination. The results suggest that immunization with subunit bacterin could reduce clinical sign and lung lesion, which is more efficacious than bacterins.

Key words: Subunit bacterin, Commercial bacterin, Antibody, Protective efficacy

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