非洲猪瘟——我国养猪业的重大威胁

doi:10.3864/j.issn.0578-1752.2018.21.016

Abstract

Abstract:

African swine fever (ASF) is a devastating disease of domestic and wild pigs caused by African swine fever virus (ASFV), and causes signi?cant economic losses to the pig industry in affected countries. Acute disease is characterized by high fever, hemorrhages in the skin and internal organs, and a high mortality rate up to 100%. The continuous spread of the disease through Africa, Europe and Russian Federation keeps the neighboring countries on heightened alert. In August 2018, ASF emerged in China for the first time and subsequently rapidly spread across many regions of China, posing a major threat to the Chinese pig industry. Considering unavailability of ASF vaccines, rapid and early diagnostic assays are urgently needed for on-site field testing. Developing an effective ASF vaccine continues to be challenging due to incomplete understanding of the virus. Recent attempts on attenuated live vaccines and gene-deleted vaccines have been reported with promising efficacy, which have been demonstrated to provide effective homologous protection and partial heterologous protection. This review summarizes the epidemiology, diagnostics, vaccines and control strategies and challenges of ASF.

Key words: African swine fever, China, epidemiology, diagnostics, vaccine, control strategy

YuZi LUO,Yuan SUN,Tao WANG,HuaJi QIU. African Swine Fever: A Major Threat to the Chinese Swine Industry[J].Scientia Agricultura Sinica, 2018, 51(21): 4177-4187.

Figures/Tables 4

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