中国两大优势产区小麦重金属镉含量调查与膳食暴露评估

doi:10.3864/j.issn.0578-1752.2015.19.009

摘要/Abstract

摘要： 【目的】分析中国两大小麦优势产区小麦重金属镉的污染水平和特点，明确不同消费人群食用小麦引起的镉膳食暴露风险，以期为中国农产品质量安全监管提供科学依据。【方法】在中国黄淮海和长江中下游两大小麦优势产区的8个省（市）采集2013年收获的小麦样品393份，利用低温消解进行前处理，通过石墨炉原子吸收分光光度计测定全部小麦样品中镉浓度，分析不同区域不同品种小麦镉的含量差异。结合中国不同消费人群的小麦消费数据和体重信息，利用非参数概率方法对小麦镉的膳食暴露量进行评估。【结果】中国两大小麦优势产区的小麦镉含量均值为（0.032±0.051）mg·kg^-1，97.5%的小麦样本镉含量低于国家限量要求。长江中下游优势产区的小麦镉含量均值为（0.060±0.091）mg·kg^-1，黄淮海优势产区的小麦镉含量均值为（0.024±0.025）mg·kg^-1，长江中下游小麦优势产区的小麦镉含量水平显著高于黄淮海小麦优势产区的小麦镉含量水平，不同品种、同一品种的小麦镉含量也存在一定的差异。中国不同消费人群对于小麦镉的膳食暴露风险不同，总体表现为：农村高于城市，低龄高于高龄，18岁以下的消费人群呈现女性高于男性，18岁以上的消费人群则呈现男性高于女性的特点。中国不同消费人群对于小麦镉的平均暴露量为国际食品添加剂联合专家委员会（JECFA）推荐的PTMI（暂定每月耐受摄入量：25 μg·kg^-1 bw）的9.0%—16.8%，P97.5百分位数暴露量为PTMI的28.9%—53.8%，暴露量最高值出现在4—7岁女童，暴露量最低值出现在60—70岁女性。中国城市消费人群对于小麦镉的膳食暴露风险表现为：低龄高于高龄，男性高于女性，但60—70岁的城市消费人群中女性偏高于男性，并且城市女性消费人群中14—18岁和45—60岁两个年龄段的暴露量偏低，中国城市消费人群对于小麦镉的平均暴露量为PTMI的7.3%—13.1%，P97.5百分位数暴露量为PTMI的23.4%—42.2%，暴露量最高值出现在4—7岁男童，暴露量最低值出现在14—18岁女性。中国农村消费人群对于小麦镉的暴露量呈现与全国类似的规律，平均暴露量为PTMI的9.6%—17.9%，P97.5百分位数暴露量为PTMI的30.9%—57.4%，暴露量最高值出现在4—7岁女童，暴露量最低值出现在60—70岁女性。【结论】中国黄淮海小麦优势产区和长江中下游小麦优势产区的小麦受到的重金属镉污染程度较轻，区域间和品种间差异都较为明显。中国不同消费人群对于小麦镉的膳食暴露风险不同，食用这些区域生产的小麦引起的镉暴露量较低，且风险在可接受的水平。

关键词: 小麦, 小麦优势产区, 镉, 膳食暴露

Abstract: 【Objective】 The objective of this study is to analyze the variation and characteristics of cadmium levels in wheat of two main wheat-producing regions in China and assess the risk degree and law of cadmium in wheat from dietary exposure to different consumer groups. Results of this study could provide a scientific basis for the supervision of quality and safety of agro-products in China.【Method】 A total of 393 wheat samples were collected from two main wheat-producing regions of Huang-Huai-Hai and the middle and lower reaches of the Yangtze River, including 8 provinces (cities). The wheat samples were treated with nitric acid and hydrogen peroxide solution by low-temperature digestion. The cadmium contents of the samples were detected by graphite furnace atomic absorption spectrophotometer (GFAAS). A non-parameter probabilistic model was used to assess the dietary exposure risk based on the information of wheat consumption and body weight of target populations. 【Result】The mean of cadmium contents of wheat in China’s two main wheat-producing regions was (0.032±0.051) mg·kg^-1, and cadmium contents in 97.5% wheat samples were below maximum allowable concentration (MAC). The average content of cadmium in wheat was (0.060±0.091) mg·kg^-1 in the middle and lower reaches of Yangtze River region, while the level was (0.024±0.025) mg·kg^-1 in Huang-Huai-Hai region. The cadmium levels of wheat in the middle and lower reaches of Yangtze River region were significantly higher than those in Huang-Huai-Hai region. There were different cadmium concentrations of wheat between different planting regions. Also it showed difference in the same variety from area to area. Considering the disparity of age and the difference of city and countryside, generally, differences were found in dietary exposure among the various consumer groups all over the country. Different consumption groups with exposure levels of cadmium in wheat had an overweighed ranking for the groups of countryside, younger ages, respectively. Considering the disparity of gender, the exposure levels of cadmium in wheat in females were higher than the levels in males (age＜18 years old). When the age ＞18 years old, the opposite case presented. The percent ratio of the mean of the assessed dietary exposure value to PTMI recommended by JECFA (Joint FAO/WHO Expert Committee on Food Additives, Provisional tolerance monthly intake: 25 μg·kg^-1 bw) was in the range of 9.0%-16.8%, the 97.5th percentile level was from 28.9% to 53.8%. The highest exposure level occurred in girls of 4-7 years old, and the lowest was found in women of 60-70 years old. In the city, considering the disparity of age and gender, the different consumption groups with exposure levels of cadmium in wheat have an overweighed ranking for the groups of younger ages and masculinity, respectively. Although the exposure level of females was higher than those of males in the age of 60-70 years old and there were lower exposure levels in the age of 14-18 and 45-60 years old in females in the city. The percent ratio of the mean of the assessed dietary exposure value to PTMI was in the range of 7.3%-13.1%, the 97.5th percentile level was from 23.4% to 42.2%. The highest exposure level occurred in boys of 4-7 years old, and the lowest was found in women of 14-18 years old. The assessed dietary exposure level of rural consumer groups had the similar rules of all over the country, the exposure value in the countryside to PTMI was in the range of 9.6%-17.9%, and the 97.5th percentile level was from 30.9% to 57.4%. The highest exposure level appeared in girls of 4-7 years old, and the lowest was found in women of 60-70 years old. 【Conclusion】 The study showed that the cadmium pollution in wheat was at lower level. There were significant differences in cadmium contents of wheat among the areas and within the varieties. The differences were found in dietary exposure among the various consumer groups. The probability of health risk of cadmium via wheat exposure was at the acceptable level.

Key words: wheat, main wheat-producing regions, cadmium, dietary exposure

陆美斌，陈志军，李为喜，胡学旭，李静梅，王步军. 中国两大优势产区小麦重金属镉含量调查与膳食暴露评估[J]. 中国农业科学, 2015, 48(19): 3866-3876.

LU Mei-bin, CHEN Zhi-jun, LI Wei-xi, HU Xue-xu, LI Jing-mei, WANG Bu-jun. Survey and Dietary Exposure Assessment of Cadmium in Wheat from Two Main Wheat-Producing Regions in China[J]. Scientia Agricultura Sinica, 2015, 48(19): 3866-3876.

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参考文献

[1] 苏婧怡. 贝类中重金属镉的风险评估[D]. 青岛: 中国海洋大学, 2012.

Su Q Y. Study on risk assessment of cadmium in mollusks[D]. Qingdao: Ocean University of China, 2012. (in Chinese)

[2] 任继平, 李德发, 张丽英. 镉毒性研究进展. 动物营养学报, 2003, 15(1): 1-6.

Ren J P, Li D F, Zhang L Y. Advances of the toxic ology of cadmium. Acta Zoonutrimenta Sinica, 2003, 15(1): 1-6. (in Chinese)

[3] 周新华. 镉对小鼠卵巢颗粒细胞凋亡作用及相关影响因素的研究[D]. 长沙: 湖南农业大学, 2006.

Zhou X H. The study on cadmium induced apoptosis of mouse granulosa cells and correlation influence factor[D]. Changsha: Hunan Agricultural University, 2006. (in Chinese)

[4] CAC. Report of the 36th session of the Codex Committee on Food Additives and Contaminant, 2004.

[5] 钱永忠, 李耘. 农产品质量安全风险评估-原理、方法和应用. 北京: 中国标准出版社, 2007.

Qian Y Z, Li Y. Risk Assessment for Quality and Safety of Agro-foods: Principles, Methodologies and Applications. Beijing: Standards Press of China, 2007. (in Chinese)

[6] 刘潇威, 陈春, 宇妍, 林繁. 农产品重金属风险评估体系的研究进展. 北京工商大学学报: 自然科学版, 2012, 30(5): 19-22.

Liu X W, Chen C, Yu Y, Lin F. Research progress of risk assessment of heavy metals in agricultural products quality and safety. Journal of Beijing Technology and Business University: Natural Science Edition, 2012, 30(5): 19-22. (in Chinese)

[7] FAO/WHO. Evaluation of certain food additives and contaminants (Thirty-third report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Technical Report Series, No. 776, 1989.

[8] FAOAVHO. Evaluation of certain food additives and contaminants (Fifty-fifth report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Technical Report Series, No. 901, 2001.

[9] FAO/WHO. Evaluation of certain food contaminants (Sixty-fourth report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Technical Report Series, No. 930, 2005.

[10] FAO/WHO. Evaluation of certain food additives and contaminants (Seventy-third report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Technical Report Series, No. 960, 2011.

[11] Corguinha A P B, de Souza G A, Goncalves V C, Carvalho C D, de Lima W E A, Martins F A D, Yamanaka C H, Francisco E A B, Guilherme L R G. Assessing arsenic, cadmium, and lead contents in major crops in Brazil for food safety purposes. Journal of Food Composition and Analysis, 2015, 37: 143-150.

[12] Khan K, Lu Y L, Khan H, Ishtiaq M, Khan S, Waqas M, Wei L, Wang T Y. Heavy metals in agricultural soils and crops and their health risks in Swat District, northern Pakistan. Food and Chemical Toxicology, 2013, 58: 449-458.

[13] Bermudez G M A, Jasan R, Pla R, Pignata M L. Heavy metal and trace element concentrations in wheat grains: assessment of potential non-carcinogenic health hazard through their consumption. Journal of Hazardous Materials, 2011, 193: 264-271.

[14] Huang M L, Zhou S L, Sun B, Zhao Q G. Heavy metals in wheat grain: Assessment of potential health risk for inhabitants in Kunshan, China. Science of the Total Environment, 2008, 405: 54-61.

[15] 王晓, 许爱芹, 强艳艳, 时应征, 周栋. 徐州北郊农业区土壤和小麦籽粒重金属污染研究. 安徽农业科学, 2008, 36(3): 1124-1125.

Wang X, Xu A Q, Zhang Y Y, Shi Y Z, Zhou D. Study on the pollution from heavy metal on wheat grain and soil in the northern suburb of Xuzhou City. Journal of Anhui Agricultural Sciences, 2008, 36(3): 1124-1125. (in Chinese)

[16] 李晓燕, 陈同斌, 谭勇壁, 付本田, 杨军, 宋波, 杨苏才, 谢云峰. 北京市小麦籽粒的重金属含量及其健康风险分析. 地理研究, 2008, 27(6): 1341-1346.

Li X Y, Chen T B, Tan Y B, Fu B T, Yang J, Song B, Yang S C, Xie Y F. Concentrations and risk of heavy metals in grain of wheat grown in Beijing. Geographical Research, 2008, 27(6): 1341-1346. (in Chinese)

[17] 孙卉, 韩晋仙, 马建华. 开封市化肥河污灌区小麦重金属含量及其健康风险评价. 农业环境科学学报, 2008, 27(6): 2332-2337.

Sun H, Han J X, Ma J H. Health Risk assessment of wheat seeds heavy metals in the sewage irrigation area of Huafei River, Kaifeng City. Journal of Agro-Environment Science, 2008, 27(6): 2332-2337. (in Chinese)

[18] Boon P E, van der Voet H, van Klaveren J D. Validation of a probabilistic model of dietary exposure to selected pesticides in Dutch infants. Food Additives and Contaminants, 2003, 20(Suppl.): 36-49.

[19] Gibney M J, van der Voet H. Introduction to the Monte Carlo project and the approach to the validation of probabilistic models of dietary exposure to selected food chemicals. Food Additives and Contaminants, 2003, 20(Suppl. 1): 1-7.

[20] Ferrier H, Nieuwenhuijsen M, Boobis A, Elliott P. Current knowledge and recent developments in consumer exposure assessment of pesticides: a UK perspective. Food Additives and Contaminants, 2002, 19: 837-852.

[21] Paulo M J, van der Voet H, Jansen M J W, ter Braak C J F, van Klaveren J D. Risk assessment of dietary exposure to pesticides using a Bayesian method. Pest Management Science, 2005, 61: 759-766.

[22] 隋海霞, 贾旭东, 刘兆平, 李凤琴, 严卫星. 食品中化学物膳食暴露评估数据的来源选择原则及不确定性分析. 卫生研究, 2011, 40(6): 791-794.

Sui H X, Jia X D, Liu Z P, Li F Q, Yan W X. Sources, selection principles and uncertainty analysis of data on dietary exposure assessment of chemicals in foods. Journal of Hygiene Research, 2011, 40(6): 791-794. (in Chines)

[23] Kroes R, Müller D, Lambe J. Assessment of intake from the diet. Food and Chemical Toxicology, 2002(2/3): 327-385.

[24] 翟凤英, 杨晓光. 中国居民营养与健康状况调查报告之二-2002膳食与营养素摄入状况. 北京: 人民卫生出版社, 2006: 145-146.

Zhai F Y, Yang X G. A Survey on the Chinese National Health and NutritionⅡ: The National Diet and Nutrition in 2002. Beijing: Peoples Medical Publishing House, 2006: 145-146. (in Chinese)

[25] 杨晓光, 翟凤英. 中国居民营养与健康状况调查报告之三-2002居民体质与营养状况. 北京: 人民卫生出版社, 2006: 55-58.

Yang X G, Zhai F Y. A Survey on the Chinese National Health and Nutrition Ⅲ: The Resident Constitution and Nutrition in 2002. Beijing: Peoples Medical Publishing House, 2006: 55-58. (in Chinese)

[26] 陈志军, 许扬, 宋雯, 钱永忠, 王敏, 徐辰武. 基于U-V模拟分析方法的农产品安全风险评估模型研究. 农产品质量与安全, 2013, 6: 52-59.

Chen Z J, Xu Y, Song W, Qian Y Z, Wang M, Xu C W. Study on agro-products safety risk assessment model based on U-V simulation analysis. Agricultural Quality and Standards, 2013, 6: 52-59. (in Chinese)

[27] Efron B, Tibshirani R J. An Introduction to the Bootstrap. New York: Chapman & Hall, 1993: 14-15, 275.

[28] 陈志军, 宋雯, 李培武, 丁小霞, 王敏, 钱永忠. 中国花生中镉含量调查与膳食风险评估. 农业环境科学学报, 2012, 31(2): 237-244.

Cheng Z J, Song W, Li P W, Ding X X, Wang M, Qian Y Z. Survey and dietary risk assessment of cadmium in peanut produced in China. Journal of Agro-Environment Science, 2012, 31(2): 237-244. (in Chinese)

[29] 中华人民共和国卫生部. GB 2762-2012. 食品安全国家标准食品中污染物限量[S]. 北京: 中国标准出版社, 2012.

Ministry of Health of the People’s Republic of China. GB 2762-2012. National Food Safety Standards for Maximum Levels of Contaminants in Foods[S]. Beijing: Standards Press of China, 2012. (in Chinese)

[30] 京华时报. 中国绘制土壤重金属污染图-部分城市放射性异常[EB/OL]. http://news.qq.com/a/20130613/000535.htm. 2013-6-13.

Jinghua Times. China draws the pollution map of heavy metals in soil: There has abnormal radioactivity in some cities[EB/OL]. http://news.qq.com/a/20130613/000535.htm. 2013-6-13. (in Chinese)

[31] 高巍, 耿月华, 赵鹏, 睢福庆, 王巧燕, 甘万祥. 不同小麦品种对重金属镉吸收及转运的差异研究. 天津农业科学, 2014, 20(10): 55-59.

Gao W, Geng Y H, Zhao P, Sui F Q, Wang Q Y, Gan W X. Differences of cadmium absorption and transfer between high-accumulating and low-accumulating wheat varieties. Tianjin Agricultural Sciences, 2014, 20(10): 55-59. (in Chinese)

[32] Khan M U, Malik R N, Muhammad S. Human health risk from heavy metal via food crops consumption with waste water irrigation practices in Pakistan. Chemosphere, 2013, 93: 2230-2238.

[33] Mirei U, Etsuko K, Yasushi S. Cadmium exposure aggravates mortality more in women than in men. International Journal of Environmental Health Research, 2006, 16(4): 273-279.

[34] Nadal M, Schuhmacher M, Domingoa J L. Metal pollution of soils and vegetation in an area with petrochemical industry. Science of the Total Environment, 2004, 321: 59-69.

[35] Zheng N, Wang Q C, Zheng D M. Health risk of Hg, Pb, Cd, Zn, and Cu to the inhabitants around Huludao zinc plant in China via consumption of vegetables. Science of the Total Environment, 2007, 383: 81-89.

[36] 高俊全, 李筱薇, 赵京玲. 2000年中国总膳食研究: 膳食铅、镉摄入量. 卫生研究, 2006, 35(6): 750-754.

Gao J Q, Li X W, Zhao J L. In 2000 Chinese total diet study: the dietary lead and cadmium intakes. Journal of Hygiene Research, 2006, 35(6): 750-754. (in Chinese)

[37] 张磊, 高俊全, 李筱薇. 2000年中国总膳食研究—不同性别年龄组人群膳食镉摄入量. 卫生研究, 2008, 37(3): 338-342.

Zhang L, Gao J Q, Li X W. Chinese total diet study in 2000-Cadmium intakes by different age-sex population groups. Journal of Hygiene Research, 2008, 37(3): 338-342. (in Chinese)

[38] 张存政, 张心明, 田子华, 何丹军, 刘贤金. 稻米中毒死蜱和氟虫腈的残留规律及其暴露风险. 中国农业科学, 2010, 43(1): 151-163.

Zhang C Z, Zhang X M, Tian Z H, He D J, Liu X J. Degradation of chlorpyrifos and fipronil in rice from farm to dining table and risk assessment. Scientia Agricultura Sinica, 2010, 43(1): 151-163. (in Chinese)

[39] 张志恒, 汤涛, 徐浩, 李振, 杨桂玲, 王强. 果蔬中氯吡脲残留的膳食摄入风险评估. 中国农业科学, 2012, 45(10): 1982-1991.

Zhang Z H, Tang T, Xu H, Li Z, Yang G L, Wang Q. Dietary intake risk assessment of forchlorfenuron residuein fruits and vegetables. Scientia Agricultura Sinica, 2012, 45(10): 1982-1991. (in Chinese)

[40] Van der Voet H, Slob W. Integration of probabilistic exposure assessment and probabilistic hazard characterization. Risk Analysis, 2007, 27(2): 351-371.

[41] 韩迪, 徐勇. 中国1985与2010年不同地区青少年身高体重比较. 中国学校卫生, 2014, 35(5): 700-703.

Han D, Xu Y. Regional variation in physical growth among children and adolescents in China during1985-2010. Chinese Journal of School Health, 2014, 35(5): 700-703. (in Chinese)

[42] 李宁, 于传友, 刘晓冰, 于泉福, 赵侠, 刘滢, 于娣. 辽宁省城市居民身高、体重、BMI 10年比较研究. 中国健康教育, 2014, 30(8): 691-697.

Li N, Yu C Y, Liu X B, Yu Q F, Zhao X, Liu Y, Yu D. Compared analysis on height, weight and body mass index among urban residents in Liaoning Province between 1999 and 2009. Chinese Journal of Health Education, 2014, 30(8): 691-697. (in Chinese)

[43] 李忠, 唐振柱, 方志峰, 杨虹, 王启, 赵琳, 刘展华, 陈玉柱, 陆武韬. 1991-2011年广西18-65岁居民身高体重变化趋势分析. 热带医学杂志, 2014, 14(2): 229-232.

Li Z, Tang Z Z, Fang Z F, Yang H, Wang Q, Zhao L, Liu Z H, Chen Y Z, Lu W T. Analysis of the height and weight trends among Guangxi people aged 18-65 from 1991 to 2011. Journal of Tropical Medicine, 2014, 14(2): 229-232. (in Chinese)

[44] 王玉庭. 中国小麦消费现状及趋势分析. 中国食物与营养, 2010(5): 47-50.

Wang Y T. Status of wheat consumption and its trend in China. Food and Nutrition in China, 2010(5): 47-50. (in Chinese)

[45] Boon P E, Ruprich J, Petersen A, Moussavian S, Debegnach F, van Klaveren J D. Harmonisation of food consumption data format for dietary exposure assessments of chemicals analysed in law agricultural commodities. Food and Chemical Toxicology, 2009, 47(12): 2883-2889.