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| Experimental infectivity of Theileria luwenshuni and Theileria uilenbergi in Chinese Kunming mice |
| LI You-quan1, 2, GUO Peng-fei1, LIU Jun-long1, LIU Zhi-jie1, HAN Yuan1, LI Xuan1, LIU Ai-hong1, GUAN Gui-quan1, 2, LIU Guang-yuan1, 2, LUO Jian-xun1, 2, YIN Hong1, 2 |
1 State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, P.R.China
2 Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, P.R.China |
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Abstract Theileria luwenshuni and Theileria uilenbergi are important tick-borne pathogens and cause substantial losses to the sheep industry in China. The improvement in detection techniques has allowed the identification of multi-homing parasitism in Theileria parasites. Herein we evaluated the experimental infectivity of T. luwenshuni and T. uilenbergi in Chinese Kunming mice by screening blood samples of experimentally inoculated mice by microscopic examination (ME) and PCR. T. luwenshuni infected Chinese Kunming mice and 20 mice inoculated with this parasite were positive by ME and PCR. In addition, T. uilenbergi infected mice and 20 mice inoculated with this species were positive by ME and PCR. However, the number of red blood cells and the levels of hemoglobin of 40 infected mice had no obvious changes in the course of infection. Our results demonstrated the multi-homing parasitism of T. luwenshuni and T. uilenbergi, which were believed to be parasites of sheep and goats. This study was the first to demonstrate the infection of T. luwenshuni and T. uilenbergi in Kunming mice.
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Received: 04 September 2017
Accepted:
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| Fund: This study was financially supported by the National Key Research and Development Program of China (2017YFD0501200, 2016YFC1202000, 2016YFC1202002), the earmarked fund for China Agriculture Research System (CARS-37), the National natural science foundation of china (31272556, 31402189, 31372432), the Agricultural Science and Technology Innovation Program, China (2014ZL010), the National Basic Research Program of China (2015CB150300), the Special Funds for Agro-scientific Research in the Public Research, China (201303035), the Gansu International Collaboration Special Project, China (1504WKCA056), the Jiangsu Co-Innovation Center Programme for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, State Key Laboratory of Veterinary Etiological Biology Project, China. |
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Corresponding Authors:
Correspondence YIN Hong, E-mail: yinhong@caas.cn; LUO Jian-xun, E-mail: luojianxun@caas.cn
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| About author: LI You-quan, Tel: +86-931-8342515, Fax: +86-931-8340977, E-mail: youquan-li@caas.cn |
Cite this article:
LI You-quan, GUO Peng-fei, LIU Jun-long, LIU Zhi-jie, HAN Yuan, LI Xuan, LIU Ai-hong, GUAN Gui-quan, LIU Guang-yuan, LUO Jian-xun, YIN Hong .
2018.
Experimental infectivity of Theileria luwenshuni and Theileria uilenbergi in Chinese Kunming mice. Journal of Integrative Agriculture, 17(2): 488-492.
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