Scientia Agricultura Sinica ›› 2013, Vol. 46 ›› Issue (15): 3206-3211.doi: 10.3864/j.issn.0578-1752.2013.15.015

• ANIMAL SCIENCE·VETERINARY SCIENCERE·SOURCE INSECT • Previous Articles     Next Articles

Effect of Different Levels of Vitamin D3 on Metabolism of Calcium and Phosphorus and Immune Function of Yangzhou Goslings

 TIAN  Xiao-Xiao, WANG  Zhi-Yue, YANG  Hai-Ming, CAO  Yu-Juan, SUN  Hong-Nuan   

  1. College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, Jiangsu
  • Received:2013-01-28 Online:2013-08-01 Published:2013-04-26

PDF

516

Abstract: 【Objective】The objective of this study is to study the effect of vitamin D3 (VD3) on metabolism of calcium and phosphorus and immune function of Yangzhou goslings.【Method】Three hundred 28-day-old healthy male Yangzhou geese with similar live weight were randomly allocated into 5 treatments. Six replicates per group of 10 geese for each replicate were designed. The control group was fed with a basal diet, while the experimental groups were fed with the experimental diets wich added 500 IU•kg-1, 1 000 IU•kg-1, 2 000 IU•kg-1 and 4 000 IU•kg-1 vitamin D3, respectively, until 10 weeks of age. 【Result】 Adding 1 000 IU•kg-1 vitamin D3 in a basal diet significantly increased serum calcium content, tibia calcium content, tibia strength and serum immunoglobulin IgG content of 10-week-old Yangzhou geese (P＜0.05). Compared with the control group, serum calcium content was very significantly increased when adding 2 000 IU•kg-1 vitamin D3 (P＜0.01), and thymus index and serum interleukin-4 content were significantly increased at the same vitamin D3 supplemental level (P＜0.05). There were no significant effects on phosphorus content and alkaline phosphatase(ALP) activity in serum with different vitamin D3 supplemental levels (P＞0.05).【Conclusion】Optimal diet vitamin D3 supplementation (1 000-2 000 IU•kg-1) could increase the metabolism of calcium and the immune function of Yangzhou goslings.

Key words: vitamin D3 , goslings , metabolism of calcium and phosphorus , immune function

[1]杨凤. 动物营养学. 北京: 中国农业出版社, 1999.

Yang F. Animal Nutrition Science. Beijing: China Agriculture Press, 1999. (in Chinese)

[2]Dusso A S, Brown A J, Slatopolsky E. Vitamin D. American Journal of Physiology-Renal Physiology, 2005, 289(1): F8-F28.

[3]Michel F H. Vitamin D: importance in the prevention of cancers, type 1 diabetes,heart disease,and osteoporosis. American Society for Clinical Nutrition, 2004, 79(3): 362-371.

[4]王丹莉, 罗兰.不同水平维生素A、D、E日粮对肉仔鸡生长性能、胫骨软骨症及免疫机能的影响. 中国饲料, 1996, 17: 17-18.

Wang D L, Luo L. Effects of different vitamin A, D, E levels in dietary on growth performance, tibial dyschondroplasia and immune function cholecalciferol of broilers. Chinese Journal of Feed, 1996, 17: 17-18. (in Chinese)

[5]Atencio A, Pesti G M, Edwards H M Jr. Twenty-five hydroxy cholecalciferol as a cholecalciferol substitute in broiler breeder hen diets and its effect on the performance and general health of the progeny. Poultry Science, 2005, 84(8): 277-1285.

[6]李德发, 刘焕龙, 席鹏彬, 陈勇, 李宇红. 维生素D3对断奶仔猪生长性能和免疫机能的影响. 中国农业大学学报, 2001, 6(5) : 87 -94.

Li D F, Liu H L, Xi P B, Chen Y, Li Y H. Effects of vitamin D3 on immunity and performance of weanling pigs. Journal of China Agricultural University, 2001, 6(5): 87-94. (in Chinese)

[7]Bemiss C J, Mahon B D, Henry A, Henry A, Weaver V, Cantorna M T. Interleukin-2 is one of the targets of 1,25-dihydroxyvitamin D3 in the immune system. Archives of Biochemistry and Biophysics, 2002, 402(2): 249-254.

[8]Chou S H, Chung T K, Yu B. Effects of supple-mental 25-hydroxy cholecalciferol on growth performance, small intestinal morphology, and immune response of broiler chickens. Poultry Science, 2009, 88(11): 2333-2341.

[9]Provvedini D M, Manolagas S C. 1 Alpha, 25-dihydroxyvitamin D3 receptor distribution and effects in subpopulations of normal human T lymphocytes. The Journal of Clinical Endocrinology and Metabolism, 1989, 68(4): 774-779.

[10]Meyer M B, Goetsch P D, Pike J W. A downstream intergenic cluster of regulatory enhancers contributes to the induction of CYP24A1 expression by 1alpha, 25-dihydroxyvitamin D3. The Journal of Biological Chemistry, 2010, 285(20): 15599-15610.

[11]National Research Council. Nutrient Requirement of Poultry. 9th.Revised ed. Washington DC: National Academy Press, 1994.

[12]Park S Y, Birkhold S G, Kubena L F, Nisbet D J, Ricke S C. Effect of storage condition on bone breaking strength and bone ash in laying hens at different stages in production cycles. Poultry Science, 2003, 82: 1688-1691.

[13]张丽英. 饲料分析及饲料质量检测技术. 北京: 中国农业大学出版社, 2003.

Zhang L Y. Feed Analysis and Quality Inspection Technology. Beijing: China Agriculture University Press, 2003. (in Chinese)

[14]Heaney R P. Vitamin D and calcium interactions: functional outcomes. American Journal of Clinical Nutrition, 2008, 88(2): 541-544.

[15]Demay M B, Sabbagh Y, Carpenter T O. Calcium and vitamin D: what is known about the effects on growing bone. Pediatrics, 2007, 119: 141-144.

[16]Gardiner E M, Baldock P A,Thomas G P, Sims N A, Henderson N K, Hollis B, White C P, Sunn K L, Morrison N A, Walsh W R, Eisman J A. Increased formation and decreased resorption of bone in mice with elevated vitamin D receptor in mature cells of the osteoblastic lineage. FASEB Journal, 2000, 14(13): 1908-1916.

[17]王丽, 王安, 艾涛. 维生素D对笼养育成蛋鸭生长及血液指标的影响. 东北农业大学学报, 2007, 38(3): 369-373.

Wang L, Wang A, Ai T. Effects of vitamin D levels on growth and blood parameters. Journal of Northeast Agricultural University, 2007, 38(3): 369-373. (in Chinese)

[18]韩进诚, 瞿红侠, 姚军虎, 施传信, 张春梅, 梁峰, 董先顺. 1α-羟基维生素D3和植酸酶对22-42日龄肉鸡生长性能、胫骨发育和肉品质的影响. 动物营养学报, 2011, 23(1): 102-111.

Han J C, Qu H X, Yao J H, Shi C X, Zhang C M, Liang F, Dong X S. Effects of 1α-OH D3 and phytase on growth performance, Tibia development, and meat quality of broilers aged from 22 to 42 days. Chinese Journal of Animal Nutrition, 2011, 23(1): 102-111. (in Chinese)

[19]王爽. 生长前期北京鸭维生素D需要量及日粮维生素D水平对北京鸭钙磷代谢的影响研究[D]. 北京: 中国农业科学院, 2010.

Wang S. The cholecalciferol requirement of White Pekin duckings and the effect of dietary cholecalciferol on calcium and phosphorus metabolism[D]. Beijing: Chinese Academy of Agricultural Sciences, 2010. (in Chinese)

[20]Capuano P, Radanovic T, Wanger C A, Bacic D, Kato S, Chiyama Y, St-Arnoud R, Murer H, Biber J. Intestinal and renal adaptation to a low-P-i diet of type II Na-Pi co-transporters in vitamin D receptor and 1alphaOHase-deficient mice. American Journal Physiology-Cell Physiology, 2005, 288(2): C429-C434.

[21]陆承平. 兽医微生物学. 北京: 中国农业出版社, 2006.

Lu C P. Veterinary Bacteriology. Beijing: China Agriculture Press, 2006. (in Chinese)

[22]Rivas A L, Fabricant J. Indication of immunodepression in chicken infected with various strain of Marek’s disease virus. Avian Disease, 1985, 32(1): 1-8.

[23]张淑云, 王安. 钙和维生素D对生长肉鸡免疫及抗氧化功能的影响. 动物营养学报, 2010, 22(3): 579-585.

Zhang S Y, Wang A. Effects of calcium and vitamin D on immune and antioxidant functions in growing broilers. Chinese Journal of Animal Nutrition, 2010, 22(3): 579-585. (in Chinese)

[24]李思明. 维生素D3对丝毛鸡β-防御素诱导表达及生长免疫性能的影响[D]. 雅安: 四川农业大学, 2009.

Li S M. Effects of vitamin D3 on growth performance and Induction of the β-defensins expression in silky fowl[D]. Ya’an: Sichuan Agricultural University, 2009. (in Chinese)

[25]Sedrani S H. Correlation between concentrations of humoral antibodies and vitamin D nutritional status:a survey study. European Journal of Clinical Nutrition, 1988, 42(3): 243-248.

[26]雷荣苹. 饲粮中添加VD3对四川山地乌骨鸡生长性能和免疫功能的影响[D]. 雅安: 四川农业大学, 2009.

Lei R P. Effects of added VD3 in the diet on growth performance and immune function in Sichuan Black-Bone chickens[D]. Ya’an: Sichuan Agricultural University, 2009. (in Chinese)

[27]肖玲莉, 杨毅. Th1/Th2免疫应答失衡及其影响因素. 国际儿科学杂志, 2006, 33(3): 399-402.

Xiao L L, Yang Y. The development of Th1/Th2 immune response disequilibrium and the influential factors. International Journal of Pediatrics, 2006, 33(3): 399-402.(in Chinese)

[28]Hayes C E, Nashold F E, Spach K M, Pedersen L B. The immunological functions of the vitamin D endocrine system. Cellular and Molecular Biology, 2003, 49(2): 277-300.

[29]Boonstra A, Barrat F J, Crain C, Heath V L, Savelkoul H F, O’Garra A. 1 alpha, 25-Dihydroxyvitamin D3 has a direct effect on naive CD4+T cells to enhance the development of Th2 cells. Journal of Immunology, 2001, 167(9): 4974-4980.

[30]刘红杰. 维生素D对小鼠严重烫伤后炎症反应的影响[D]. 天津: 天津医科大学, 2011.

Liu H J. Effect of vitamin D on inflammatory response in mice with sever burn[D]. Tianjin: Tianjin Medical University, 2011. (in Chinese)
[1] LIU Jiao,CHEN ZhiMin,ZHENG AiJuan,LIU GuoHua,CAI HuiYi,CHANG WenHuan. Effects of Glucose Oxidase on Growth Performance, Immune Functions and Intestinal Health of Ducks Challenged by Escherichia coli [J]. Scientia Agricultura Sinica, 2021, 54(22): 4917-4930.
[2] WANG Di, WANG Bao-Wei, GE Wen-Hua, ZHANG Ming-Ai, YUE Bin, CHEN Miao-Lu, WANG Jiao, MENG Ling-Feng. Effects of Vitamin D3 on Growth Performance, Slaughter Performance, Carcass Quality and Tibia Quality of Geese [J]. Scientia Agricultura Sinica, 2013, 46(7): 1470-1480.
[3] WANG Bao-Wei, WANG Na, GE Wen-Hua, YUE Bin, ZHANG Ming-Ai, SHI Xue-Ping. Effects of Different Selenium Sources on Production Performance, Slaughter Performance, Meat Quality, Immune and Antioxidant in the Early Goose [J]. Scientia Agricultura Sinica, 2011, 44(14): 3016-3026 .
[4] DU Jin-liang,QIN Jian-hua,CHU Jing-sheng,XU Li-na,MA Yu-zhong
. Effects of Yimu Shenghuasan on Cytochrome P450 of Endometrial Cells and Immune Function in Dairy Cows#br# [J]. Scientia Agricultura Sinica, 2010, 43(6): 1248-1254 .
[5] Lü Qiong-xia,ZHANG Shu-xia,ZHAO Ru-qian
. Effects of Transportation Stress on Expressions of IL-2, IL-6 and IL-10 mRNAs in Spleen and Regulation of Cytokines in Pigs
 [J]. Scientia Agricultura Sinica, 2010, 43(3): 578-584 .
[6] Lü Qiong-xia,ZHANG Shu-xia,ZHAO Ru-qian. Effects of Transportation Stress on Immune Function and Regulation of Cytokines in Pigs#br# [J]. Scientia Agricultura Sinica, 2009, 42(7): 2579-2585 .
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
京ICP备09089781号-30
Copyright 2018 © Editorial office of Scientia Agricultura Sinica
Tel: 86-010-82106279    E-mail: zgnykx@mail.caas.net.cn
Supported by Beijing Magtech Co.Ltd