Abstract: As the shortage of the score system of HMW-GS formerly, 100 spring wheat varieties were selected to study the relationship between HMW-GS and hand-extended noodle score indexes in wheat by quantity theory and statistics estimation. Eight multiple regression equations could be used to forecast the eight hand-extended noodle score indexes, because the determination coefficient were all upwards of 0.98. The score system of HMW-GS on hand-extended noodle score indexes was established in wheat. The HMW-GS 1, 2*, 17+18, 5+10 and 10 were good quality subunits for hand-extended noodle, HMW-GS 5+10 could improve all of the hand-extended noodle score indexes, HMW-GS 1 could improve the color of hand-extended noodle. The role of HMW-GS 17+18 was as most same as HMW-GS 5+10. So, noodle wheat should possess the HMW-GS 1, 17+18 and 5+10. HMW-GS 2+10, 2+11 and 2+12 were the worst subunits for hand-extended noodle.