|
Special Issue:
动物营养合辑Animal Nutrition
|
|
|
|
| Effect of dietary calcium or phosphorus deficiency on bone development and related calcium or phosphorus metabolic utilization parameters of broilers from 22 to 42 days of age |
YANG Yun-feng1*, XING Guan-zhong1, 3*, LI Su-fen3, SHAO Yu-xin1, ZHANG Li-yang1, LU Lin1, LUO Xu-gang2, LIAO Xiu-dong1 |
1 Mineral Nutrition Research Division, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.China
2 Poultry Mineral Nutrition Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou 225000, P.R.China
3 College of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, P.R.China |
|
|
|
|
Abstract This experiment was conducted to investigate the effect of dietary calcium (Ca) or phosphorus (P) deficiency on bone development and related Ca or P metabolic utilization parameters of broilers from 22 to 42 days of age based on our previous study, which indicated that dietary Ca or P deficiency impaired the bone development by regulating related Ca or P metabolic utilization parameters of broilers from 1 to 21 days of age. A total of 504 one-day-old Arbor Acres male broilers were randomly assigned to 1 of 4 treatments with 7 replicates in a completely randomized design, and fed the normal control and Ca- or P-deficient diets from 1 to 21 days of age. At 22 days of age, the broilers were further fed the normal control diet (0.90% Ca+0.35% non-phytate P (NPP)), the P-deficient diet (0.90% Ca+0.18% NPP), the Ca-deficient diet (0.30% Ca+0.35% NPP) or the Ca and P-deficient diet (0.30% Ca+0.18% NPP), respectively. The results showed that dietary Ca or P deficiency decreased (P<0.05) tibia bone mineral density (BMD), bone breaking strength (BBS), ash content, tibia ash Ca content and serum P content on days 28 and 42, but increased (P<0.05) tibia alkaline phosphatase (ALP) activity of broilers on day 42 compared with the control group. Furthermore, the broilers fed the P-deficient diet had the lowest (P<0.05) tibia BMD, BBS, ash content, serum P content and the highest (P<0.05) serum Ca content on day 28 compared with those fed the Ca-deficient or Ca and P-deficient diets. The results from the present study indicated that the bone development and related Ca or P metabolic utilization parameters of broilers were the most sensitive to dietary P deficiency, followed by dietary Ca deficiency or Ca and P-deficiency; dietary Ca or P deficiency impaired the bone development possibly by regulating serum Ca and P contents as well as tibia Ca content and ALP activity of broilers from 22 to 42 days of age.
|
|
Received: 13 November 2019
Accepted:
|
| Fund: The present study was financially supported by the National Key R&D Program of China (2017YF0502200), the Key Program of the National Natural Science Foundation of China (31630073), the earmarked fund for China Agriculture Research System (CARS-41), the Agricultural Science and Technology Innovation Program, China (ASTIP-IAS09), and the earmarked fund for Hebei Chicken Innovation Team of Modern Agro-Industry Technology Research System, China (HBCT2018150203 and HBCT2018150206). |
|
Corresponding Authors:
Correspondence LUO Xu-gang, E-mail: wlysz@263.net; LIAO Xiu-dong, E-mail: liaoxd56@163.com
|
| About author: YANG Yun-feng, E-mail: 604345120@163.com; * These authors contributed equally to this study. |
Cite this article:
YANG Yun-feng, XING Guan-zhong, LI su-fen, SHAO Yu-xin, ZHANG Li-yang, LU Lin, LUO Xu-gang, LIAO Xiu-dong.
2020.
Effect of dietary calcium or phosphorus deficiency on bone development and related calcium or phosphorus metabolic utilization parameters of broilers from 22 to 42 days of age. Journal of Integrative Agriculture, 19(11): 2775-2783.
|
Akter M, Graham H, Iji P A. 2016. Response of broiler chickens to different levels of calcium, non-phytate phosphorus and phytase. British Poultry Science, 57, 799–809.
AOAC (Association of Official Analytical Chemists). 2000. Official Methods of Analysis. 17th ed. Association of Official Analytical Chemists, Arlington, VA, USA.
Bar A, Rosenberg J, Perlman R, Hurwitz S. 1987. Field rickets in turkeys: Relationship to vitamin D. Poultry Science, 66, 68–72.
Berndt T, Kumar R. 2009. Novel mechanisms in the regulation of phosphorus homeostasis. Physiology, 24, 17–25.
Blahos J, Care A D, Sommerville B S. 1987. Effect of low calcium and low phosphorus diets on duodenal and ileal absorption of phosphate in chick. Endocrinologia Experimentalis, 21, 59–64.
Bradbury E J, Wilkinson S J, Cronin G M, Thomson P C, Bedford M R, Cowieson A J. 2014. Nutritional geometry of calcium and phosphorus nutrition in broiler chicks. Growth performance, skeletal health and intake arrays. Animal, 8, 1071–1079.
Christensen J W, Nielsen B L, Young J, Noddegaard F. 2003. Effects of calcium deficiency in broilers on the use of outdoor areas, foraging activity and production parameters. Applied Animal Behaviour Science, 82, 229–240.
Crenshaw T D, Peo E R, Lewis A J, Moser B D. 1981. Bone strength as a trait for assessing mineralization in swine: A critical review of techniques involved. Journal of Animal Science, 53, 827–835.
Dilworth B C, Day E J. 1965. Effect of varying dietary calcium: Phosphorus ratios on tibia and femur composition of the chick. Poultry Science, 44, 1474–1479.
Driver J P, Pesti G M, Bakalli R I, Edwards H M. 2005. Effects of calcium and nonphytate phosphorus concentrations on phytase efficacy in broiler chicks. Poultry Science, 89, 1406–1414.
Driver J P, Pesti G M, Bakalli R I, Edwards H M. 2006. The effect of feeding calcium- and phosphorus-deficient diets to broiler chickens during the starting and growing-finishing phases on carcass quality. Poultry Science, 85, 1939–1946.
Ebrahimi H, Shariatmadari F, Torshizi M A K. 2016. Dietary supplementation and in ovo injection of 1α-OHD3 in a low-calcium and low-phosphorous diets for broilers. Journal of Applied Animal Research, 44, 113–117.
Goldenberg H, Fernandez A. 1966. Simplified method for the estimation of inorganic phosphorus in body fluids. Clinical Chemistry, 12, 871–882.
Han J C, Ma K, Wang J G, Chen G H, Zhang J L, Qu H X, Yan Y F, Chen Y H. 2015. Effects of non-phytate phosphorus and 1α-hydroxycholecalciferol on growth performance, bone mineralization, and carcass traits of broiler chickens. Revista Brasileira de Ciência Avícola, 17, 503–510.
Hurwitz S, Griminger P. 1961. The response of plasma alkaline phosphatase, parathyroids and blood and bone minerals to calcium intake in the fowl. The Journal of Nutrition, 73, 177–185.
Jiang S, Cui L, Shi C, Ke X, Luo J, Hou J. 2013. Effects of dietary energy and calcium levels on performance, egg shell quality and bone metabolism in hens. Veterinary Journal, 198, 252–258.
Jiang Y, Lu L, Li S F, Wang L, Zhang L Y, Liu S B, Luo X G. 2016. An optimal dietary non-phytate phosphorus level of broilers fed a conventional corn-soybean meal diet from 4 to 6 weeks of age. Animal, 10, 1626–1634.
Kay H D. 1932. Phosphatase in growth and disease of bone. Physiological Reviews, 12, 384–422.
Leytem A B, Willing B P, Thacker P A. 2008. Phytate utilization and phosphorus excretion by broiler chickens fed diets containing cereal grains varying in phytate and phytase content. Animal Feed Science and Technology, 146, 160–168.
Li J, Yuan J, Guo Y, Sun Q, Hu X. 2012. The influence of dietary calcium and phosphorus imbalance on intestinal NaPi-IIb and Calbindin mRNA expression and tibia parameters of broilers. Asian-Australasian Journal of Animal Sciences, 25, 552–558.
Li T T, Xing G Z, Shao Y X , Zhang L Y, Li S F, Lu L, Liu Z P, Liao X D, Luo X G. 2020. Dietary calcium or phosphorus deficiency impairs the bone development by regulating related calcium or phosphorus metabolic utilization parameters of broilers. Poultry Science, 99, 3207–3214.
Li X H, Zhang D G, Bryden W L. 2017. Calcium and phosphorus metabolism and nutrition of poultry: Are current diets formulated in excess? Animal Production Science, 57, 2304–2310.
Liu S B, Liao X D, Lu L, Li S F, Wang L, Zhang L Y, Luo X G. 2017. Dietary non-phytate phosphorus requirement of broilers fed a conventional corn-soybean meal diet from 1 to 21 d of age. Poultry Science, 96, 151–159.
Luo X G, Ji F, Lin Y X, Steward F A, Lu L, Liu B, Yu S X. 2005. Effects of dietary supplementation with copper sulfate or tribasic copper chloride on broiler performance, relative copper bioavailability, and oxidation stability of vitamin E in feed. Poultry Science, 84, 888–893.
Motzok I. 1950. Studies on the plasma, phosphatase of normal and rachitic chicks. the assay of antirachitic preparations by a method based on the determination of plasma phosphatase activity. Biochemical Journal, 47, 199.
NRC (National Research Council). 1994. Nutrient Requirements of Poultry. 9th ed. National Academies Press, Washington, D.C.
Proszkowiec W M, Angel R. 2013. Calcium and phosphorus metabolism in broilers: Effect of homeostatic mechanism on calcium and phosphorus digestibility. The Journal of Applied Poultry Research, 22, 609–627.
Qian H, Kornegay E T, Denbow D M. 1996. Phosphorus equivalence of microbial phytase in turkey diets as influenced by calcium to phosphorus ratios and phosphorus levels. Poultry Science, 75, 69–81.
Rao R S V, Raju M V L N, Reddy M R, Pavani P. 2006. Interaction between dietary calcium and nonphytate phosphorus levels on growth, bone mineralizationand mineral excretion in commercial broilers. Animal Feed Science and Technology, 131, 133–148.
Rao R S V, Raju M V L N, Reddy M R, Pavani P, Sunder G S, Sharma R P. 2003. Dietary calcium and non-phytin phosphorus interaction on growth, bone mineralization and mineral retention in broiler starter chicks. Asian-Australasian Journal of Animal Sciences, 16, 719–725.
Rousseau X, Létourneau-Montminy M P, Même N, Magnin M, Narcy A. 2012. Phosphorus utilization in finishing broiler chickens: effects of dietary calcium and microbial phytase. Poultry Science, 91, 2829–2837.
Shafey T M. 1993. Calcium tolerance of growing chickens: Effect of ratio of dietary calcium to available phosphorus. Worlds Poultry Science Journal, 49, 5–18.
Shao Y X, Wen Q, Zhang S M, Lu L, Zhang L Y, Liao X D, Luo X G. 2019a. Dietary supplenmental vitamin D3 enhances phosphorus absorbtion and utilization by regulating gene expression of related phosphate transporters in the small intestine of broilers. British Journal of Nutrition, 121, 9–21.
Shao Y X, Xing G Z, Zhang L Y, Lu L, Li S F, Liao X D, Luo X G. 2019b. Effects of dietary calcium or phosphorus deficiency on growth performance, rickets incidence characters and tibia histological structure of broilers during 1 to 21 days of age. Chinese Journal of Animal Nutrition, 31, 2107–2118. (in Chinese)
Taylor T G, Morris K M L, Jean K. 1968. Effects of dietary excesses of vitamins A and D on some constituents of the blood of chicks. British Journal of Nutrition, 22, 713–721.
Tilgar V, Kilgas P, Viitak, A, Reynolds S J. 2008. The rate of bone mineralization in birds is directly related to alkaline phosphatase activity. Physiological and Biochemical Zoology, 81, 106–111.
Valable A S, Narcy A, Duclos M J, Pomar C, Page G, Nasir Z, Magnin M, Letourneau-Montminy M P. 2017. Effects of dietary calcium and phosphorus deficiency and subsequent recovery on broiler chicken growth performance and bone characteristics. Animal, 12, 1–9.
Venäläinen E, Valaja J, Jalava T. 2006. Effects of dietary metabolisable energy, calcium and phosphorus on bone mineralisation, leg weakness and performance of broiler chickens. British Poultry Science, 47, 301–310.
Viveros A, Brenes A, Arija I, Centeno C. 2002 Effects of microbial phytase supplementation on mineral utilization and serum enzyme activities in broiler chicks fed different levels of phosphorus. Poultry Science, 81, 1172–1183.
Williams B, Waddington D, Solomon S, Farquharson C. 2000. Dietary effects on bone quality and turnover, and Ca and P metabolism in chickens. Research in Veterinary Science, 69, 81–87.
Xie M, Wang S X, Hou S S, Huang X. 2009. Interaction between dietary calcium and non-phytate phosphorus on growth performance and bone ash in early White Pekin Ducklings. Animal Feed Science and Technology, 151, 161–166.
Yan F, Angel R, Ashwell C, Mitchell A, Christman M. 2005. Evaluation of the broiler’s ability to adapt to an early moderate deficiency of phosphorus and calcium. Poultry Science, 84, 1232–1241. |
| No Suggested Reading articles found! |
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
