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Journal of Integrative Agriculture  2015, Vol. 14 Issue (11): 2282-2295    DOI: 10.1016/S2095-3119(15)61121-2
Section 2: Detection methods and technologies Advanced Online Publication | Current Issue | Archive | Adv Search |
Immunoassay of chemical contaminants in milk: A review
 XU Fei, REN Kang, YANG Yu-ze, GUO Jiang-peng, MA Guang-peng, LIU Yi-ming, LU Yong-qiang, LI Xiu-bo
1、National Feed Drug Reference Laboratories, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081,
P.R.China
2、Beijing General Station of Animal Husbandry, Beijing 100107, P.R.China
3、China Rural Technology Development Center, Ministry of Science and Technology of China, Beijing 100045, P.R.China
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摘要  The detection of chemical contaminants is critical to ensure dairy safety. These contaminants include veterinary medicines, antibiotics, pesticides, heavy metals, mycotoxins, and persistent organic pollutants (POPs). Immunoassays have recently been used to detect contaminants in milk because of their simple operation, high speed, and low cost. This article describes the latest developments in the most important component of immunoassays — antibodies, and then reviews the four major substrates used for immunoassays (i.e., microplates, membranes, gels, and chips) as well as their use in the detection of milk contaminants. The paper concludes with prospects for further applications of these immunoassays.

Abstract  The detection of chemical contaminants is critical to ensure dairy safety. These contaminants include veterinary medicines, antibiotics, pesticides, heavy metals, mycotoxins, and persistent organic pollutants (POPs). Immunoassays have recently been used to detect contaminants in milk because of their simple operation, high speed, and low cost. This article describes the latest developments in the most important component of immunoassays — antibodies, and then reviews the four major substrates used for immunoassays (i.e., microplates, membranes, gels, and chips) as well as their use in the detection of milk contaminants. The paper concludes with prospects for further applications of these immunoassays.
Keywords:  milk       chemical contaminants       immunoassay       antibodies  
Received: 16 April 2015   Accepted:
Fund: 

This work was financially supported by the Beijing Dairy Industry Innovation Team and Feed Quality and Safety Control Innovation Team of Chinese Academy of Agricultural Sciences.

Corresponding Authors:  LI Xiu-bo,Tel: +86-10-82106059, E-mail: lixiubo@caas.cn; LU Yong-qiang,Tel: +86-10-84929001, E-mail: luyongqiang@163.com     E-mail:  lixiubo@caas.cn;luyongqiang@163.com
About author:  XU Fei, E-mail: xufei@caas.cn;

Cite this article: 

XU Fei, REN Kang, YANG Yu-ze, GUO Jiang-peng, MA Guang-peng, LIU Yi-ming, LU Yong-qiang, LI Xiu-bo. 2015. Immunoassay of chemical contaminants in milk: A review. Journal of Integrative Agriculture, 14(11): 2282-2295.

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