Bah A, Sanicas M, Nigou J, Guilhot C, Astarie-Dequeker C, Vergne I. 2020. The lipid virulence factors of Mycobacterium tuberculosis exert multilayered control over autophagy-related pathways in infected human macrophages. Cells, 9, 666.

Behar S M, Martin C J, Booty M G, Nishimura T, Zhao X, Gan H X, Divangahi M, Remold H G. 2011. Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunology, 4, 279–287.

Bernegger S, Vidmar R, Fonovic M, Posselt G, Turk B, Wessler S. 2021. Identification of desmoglein-2 as a novel target of Helicobacter pylori HtrA in epithelial cells. Cell Communication and Signaling, 19, 108.

Boehm M, Simson D, Escher U, Schmidt A M, Bereswill S, Tegtmeyer N, Backert S, Heimesaat M M. 2018. Function of serine protease HtrA in the lifecycle of the foodborne pathogen Campylobacter jejuni. European Journal of Microbiology and Immunology, 8, 70–77.

Burchacka E, Sienczyk M. 2018. The lord of the bacteria: The fellowship of the leader and other serine protease inhibitors. Current Pharmaceutical Design, 24, 4445–4465.

Chai Q, Wang L, Liu C H, Ge B. 2020. New insights into the evasion of host innate immunity by Mycobacterium tuberculosis. Cellular & Molecular Immunology, 17, 901–913.

Chen M, Gan H, Remold H G. 2006. A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis. The Journal of Immunology, 176, 3707–3723.

Cui Y, Tang Y, Shao M, Zang X, Jiang Y, Cui Z, Dang G, Liu S. 2022. Mycobacterium tuberculosis protease Rv3090 is associated with late cell apoptosis and participates in organ injuries and mycobacterial dissemination in mice. Microbial Pathogenesis, 173, 105880.

Danelishvili L, Babrak L, Rose S J, Everman J, Bermudez L E. 2014. Mycobacterium tuberculosis alters the metalloprotease activity of the COP9 signalosome. mBio, 5, e01278-14.

Dang G, Chen L, Li Z, Deng X, Cui Y, Cao J, Yu S, Pang H, Liu S. 2015. Expression, purification and characterisation of secreted esterase Rv2525c from Mycobacterium tuberculosis. Applied Microbiology and Biotechnology, 176, 1–12.

Dang G, Cui Y, Wang L, Li T, Cui Z, Song N, Chen L, Pang H, Liu S. 2018. Extracellular sphingomyelinase Rv0888 of Mycobacterium tuberculosis contributes to pathological lung injury of Mycobacterium smegmatis in mice via inducing formation of neutrophil extracellular traps. Frontiers in Immunology, 9, 677.

Diedrich C R, O’hern J, Wilkinson R J. 2016. HIV-1 and the Mycobacterium tuberculosis granuloma: A systematic review and meta-analysis. Tuberculosis, 98, 62–76.

Goettig P, Brandstetter H, Magdolen V. 2019. Surface loops of trypsin-like serine proteases as determinants of function. Biochimie, 166, 52–76.

Gomez J E, Mckinney J D. 2004. M. tuberculosis persistence, latency, and drug tolerance. Tuberculosis, 84, 29–44.

Harish B S, Uppuluri K B. 2018. Microbial serine protease inhibitors and their therapeutic applications. International Journal of Biological Macromolecules, 107, 1373–1387.

Hedstrom L. 2002. Serine protease mechanism and specificity. Chemical Reviews, 102, 4501–4524.

Howell M, Dumitrescu D G, Blankenship L R, Herkert D, Hatzios S K. 2019. Functional characterization of a subtilisin-like serine protease from Vibrio cholerae. Journal of Biological Chemistry, 294, 9888–9900.

Jain R, Dey B, Khera A, Srivastav P, Gupta U D, Katoch V M, Ramanathan V D, Tyagi A K. 2011. Over-expression of superoxide dismutase obliterates the protective effect of BCG against tuberculosis by modulating innate and adaptive immune responses. Vaccine, 29, 8118–8125.

Ladel C H, Blum C, Dreher A, Reifenberg K, Kopf M, Kaufmann S H. 1997. Lethal tuberculosis in interleukin-6-deficient mutant mice. Infection and Immunity, 65, 4843–4849.

Lee J O, Kim J Y, Rhee D K, Pyo S. 2013. Streptococcus pneumoniae ClpP protease induces apoptosis via caspase-independent pathway in human neuroblastoma cells: Cytoplasmic relocalization of p53. Toxicon, 70, 142–152.

Li H, Dang G, Liu H, Wang Z, Cui Z, Song N, Chen L, Liu S. 2019. Characterization of a novel Mycobacterium tuberculosis serine protease (Rv3194c) activity and pathogenicity. Tuberculosis, 119, 101880.

Liu C H, Liu H, Ge B. 2017. Innate immunity in tuberculosis: Host defense vs pathogen evasion. Cellular & Molecular Immunology, 14, 963–975.

Liu M, Li W, Xiang X, Xie J. 2015. Mycobacterium tuberculosis effectors interfering host apoptosis signaling. Apoptosis, 20, 883–891.

Liu W, Spero D M. 2004. Cysteine protease cathepsin S as a key step in antigen presentation. Drug News & Perspectives, 17, 357–363.

Park H S, Back Y W, Jang I T, Lee K I, Son Y J, Choi H G, Dang T B, Kim H J. 2021. Mycobacterium tuberculosis Rv2145c promotes intracellular survival by STAT3 and IL-10 receptor signaling. Frontiers in Immunology, 12, 666293.

Pieters J. 2008. Mycobacterium tuberculosis and the macrophage: Maintaining a balance. Cell Host & Microbe, 3, 399–407.

Prokesova L, Potuznikova B, Potempa J, Zikan J, Radl J, Hachova L, Baran K, Porwit-Bobr Z, John C. 1992. Cleavage of human immunoglobulins by serine proteinase from Staphylococcus aureus. Immunology Letters, 31, 259–265.

Qin S, Wang Z, Huang C, Huang P, Li D. 2022. Serine protease PRSS23 drives gastric cancer by enhancing tumor associated macrophage infiltration via FGF2. Frontiers in Immunology, 13, 955841.

Rahlwes K C, Dias B R S, Campos P C, Alvarez-Arguedas S, Shiloh M U. 2023. Pathogenicity and virulence of Mycobacterium tuberculosis. Virulence, 14, 2150449.

Rodriguez-Cabrera L, Trujillo-Bacallao D, Borras-Hidalgo O, Wright D J, Ayra-Pardo C. 2010. RNAi-mediated knockdown of a Spodoptera frugiperda trypsin-like serine-protease gene reduces susceptibility to a Bacillus thuringiensis Cry1Ca1 protoxin. Environmental Microbiology, 12, 2894–2903.

Samten B, Wang X, Barnes P F. 2009. Mycobacterium tuberculosis ESX-1 system-secreted protein ESAT-6 but not CFP10 inhibits human T-cell immune responses. Tuberculosis, 89(Suppl.1), S74–S80.

Sharafutdinov I, Esmaeili D S, Harrer A, Tegtmeyer N, Sticht H, Backert S. 2020. Campylobacter jejuni serine protease HtrA cleaves the tight junction component Claudin-8. Frontiers in Cellular and Infection Microbiology, 10, 590186.

Shin D M, Jeon B Y, Lee H M, Jin H S, Yuk J M, Song C H, Lee S H, Lee Z W, Cho S N, Kim J M, Friedman R L, Jo E K. 2010. Mycobacterium tuberculosis eis regulates autophagy, inflammation, and cell death through redox-dependent signaling. PLoS Pathogens, 6, e1001230.

Skorko-Glonek J, Figaj D, Zarzecka U, Przepiora T, Renke J, Lipinska B. 2017. The extracellular bacterial HtrA proteins as potential therapeutic targets and vaccine candidates. Current Medicinal Chemistry, 24, 2174–2204.

Sodenkamp J, Waetzig G H, Scheller J, Seegert D, Grotzinger J, Rose-John S, Ehlers S, Holscher C. 2012. Therapeutic targeting of interleukin-6 trans-signaling does not affect the outcome of experimental tuberculosis. Immunobiology, 217, 996–1004.

Spoerry C, Karlsson J, Aschtgen M S, Loh E. 2021. Neisseria meningitidis IgA1-specific serine protease exhibits novel cleavage activity against IgG3. Virulence, 12, 389–403.

Sun Y, Wang Y, Liu W, Zhou J L, Zeng J, Wang X H, Jiang Y R, Li D H, Qin L. 2017. Upregulation of a trypsin-like serine protease gene in Antheraea pernyi (Lepidoptera: Saturniidae) strains exposed to different pathogens. Journal of Economic Entomology, 110, 941–948.

Tamgue O, Gcanga L, Ozturk M, Whitehead L, Pillay S, Jacobs R, Roy S, Schmeier S, Davids M, Medvedeva Y A, Dheda K, Suzuki H, Brombacher F, Guler R. 2019. Differential targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 promotes the intracellular growth of Mycobacterium tuberculosis in alternatively IL-4/IL-13 activated macrophages. Frontiers in Immunology, 10, 421.

Velmurugan K, Chen B, Miller J L, Azogue S, Gurses S, Hsu T, Glickman M, Jacobs Jr W R, Porcelli S A, Briken V. 2007. Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells. PLoS Pathogens, 3, e110.

Wang J, Ge P, Qiang L, Tian F, Zhao D, Chai Q, Zhu M, Zhou R, Meng G, Iwakura Y, Gao G F, Liu C H. 2017. The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation. Nature Communications, 8, 244.

Wen W, Qi Z, Wang J. 2020. The function and mechanism of Enterovirus 71 (EV71) 3C protease. Current Microbiology, 77, 1968–1975.

Xu G, Jia H, Li Y, Liu X, Li M, Wang Y. 2010. Hemolytic phospholipase Rv0183 of Mycobacterium tuberculosis induces inflammatory response and apoptosis in alveolar macrophage RAW264.7 cells. Canadian Journal of Microbiology, 56, 916–924.

Yan S, Wu G. 2021. Potential 3-chymotrypsin-like cysteine protease cleavage sites in the coronavirus polyproteins pp1a and pp1ab and their possible relevance to COVID-19 vaccine and drug development. FASEB Journal, 35, e21573.

Zhang L, Zhong Q, Bao L, Zhang Y, Gao L, Huang B, Zhang H D. 2009. Rv0901 from Mycobacterium tuberculosis, a possible novel virulent gene proved through the recombinant Mycobacterium smegmatis. Japanese Journal of Infectious Diseases, 62, 26–31.

Zhao Q, Li W, Chen T, He Y, Deng W, Luo H, Xie J. 2014. Mycobacterium tuberculosis serine protease Rv3668c can manipulate the host-pathogen interaction via Erk-NF-kappaB axis-mediated cytokine differential expression. Journal of Interferon & Cytokine Research, 34, 686–698.