Scientia Agricultura Sinica ›› 2008, Vol. 41 ›› Issue (3): 823-827 .doi: 10.3864/j.issn.0578-1752.2008.03.026

• ANIMAL SCIENCE·RESOURCE INSECT • Previous Articles     Next Articles

Mapping the GAS6 Gene of Porcine to SSC11q11-17 with SCHP

  

  1. 湖南农业大学动物科技学院
  • Received:2006-11-20 Revised:2007-03-12 Online:2008-03-10 Published:2008-03-10

Abstract: Abstract: ObjectiveGAS6growth arrested-special 6is associated with adhesion, identification, survival, proliferation, differentiation, and growth of cell in human. However, little is known about gene of GAS6 of porcine. In order to map the position of the gene of GAS6 in chromosome in pigs and to found the basis of cloning this gene and studying the function of this gene, Methodwe used the Pig別rodent somatic cell hybrid panel(SCHP) and INRA-Minnesota porcine radiation hybrid panel(IMpRH). Results the isolated fragments GAS6 gene of swine was deposited into GenBank and accession number was AY880668. The results showed that the gene of GAS6 was located in the SSC11q11-17. The GAS6 gene were linkaged closely to the microsatellite SW1452 anchored on SSC11 with the rate of retension of 0.22, LOD score threshold were 16.88 and the distance in map of the radiation hybrid (RH) was 56 cR. ConclusionThat the position of GAS6 was on the SSC11q11-17 conformed to the conclusions which was drawn by means of IMpRH because the SSC11 is homologous with most of HSA11.

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