Abstract: 【aim】A HPLC/ESI/MS2 method was developed for the qualitative analysis of mogrosides from fruits of Siratia grosvenori.【method】HPLC/ESI/MS2 was used to separate and analyze mogroside extracts from fruits of Siratia grosvenori. 【result】The main components of mogroside in mogroside extracts were 11-oxo-mogroside-V, mogroside-V, mogroside-IV, mogroside-VI and siamenoside-I according to mass spectrometry analysis of main chromatogram peaks. 【conclusion】HPLC／ESI/MS2 is a convenient, rapid and effective method for separation and qualitatively analysis of mogrosides from fruits of Siratia grosvenori.

Key words: Siratia grosvenori, Mogrosides, HPLC/ESI/MS2