马传染性贫血病毒驴白细胞弱毒疫苗及免疫保护机制研究回顾与展望

Abstract

Abstract: This article summarizes a great damage caused by the equine infectious anemia virus (EIAV) to animal husbandry in China,the significance and development of the equine infectious anemia virus donkey leukocyte attenuated vaccine (EIAVDLA), and the economic improvement for the application of this vaccine. The facts reflect that our scientists made outstanding contributions for the vaccine development and immunoprotection mechanism study of EIAV vaccines.We preliminarily have clarified the genomic structure differences between EIAVDLA and native strain virus. Also the molecular basis and the immunoprotection mechanism of EIAVDLA were reported. We have established several EIAV technology platforms and evaluation systems, thus providing technical methods for the study of immunoprotection mechanism.The research results may be beneficial for other lentivirus vaccines.

Key words: Equine infectious anemia virus , Donkey leukocyte attenuated vaccine(EIAVDLA) , Immunoprotection

XIANG Wen-hua. Review and Perspects of the Equine Infectious Anemia Virus Donkey Leukocyte Attenuated Vaccine and Its Immunoprotection Mechanism[J].Scientia Agricultura Sinica, 2007, 40(增刊): 3363-3368.

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References

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Review and Perspects of the Equine Infectious Anemia Virus Donkey Leukocyte Attenuated Vaccine and Its Immunoprotection Mechanism

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