Abstract: 【Objective】The dynamic changes of multi-ingredients group in Cortex Moutan in Chongqing were studied in order to determine the best growing stage and harvesting time, and to establish a quality control method for Cortex Moutan which is more accordant with herbalist doctor theory. 【Method】 The contents of paeonol in all samples were measured and Contex Moutan samples' chromatographic fingerprints were set up at 273 nm by HPLC. The relative quantity of other ingredients were calculated using paeonol as reference substance in order to understand the dynamic process of the main ingredients in growing circle of Paeonia suffruticosa Andr. by chart analyzing.【Result】(1) The average content of paeonol is 1.25% and the content of paeonol is the highest in samples of Cortex Moutan in Chongqing harvested in Oct. and has grown for 5 years. (2) The contents of other ingredients are the highest in Nov. in the fifth year. Their dynamic changes were positively correlated with paeonol's.【Conclusion】 TCM's multi-ingredients chromatographic fingerprints technology is a modern instrument analysis method which can be used extensively for TCM's quality control. And it can be widely used in producting and circulating field.

Key words: Chuan-Cortex Moutan, multi-chemical components, Chromatographic fingerprints, quality controling, Harvesting stage