Apel K, Hirt H. 2004. Reactive oxygen species: Metabolism, oxidative stress, and signal transduction. Annual Review of Plant Biology, 55, 373−399.

Appert C, Logemann E, Hahlbrock K, Schmid J, Amrhein N. 1994. Structural and catalytic properties of the four phenylalanine ammonia-lyase isoenzymes from parsley (Petroselinum crispum Nym.). European Journal of Biochemistry, 225, 491−499.

Baker D D, Chu M, Oza U, Rajgarhia V. 2007. The value of natural products to future pharmaceutical discovery. Natural Product Reports, 24, 1225−1244.

Bassil K L, Vakil C, Sanborn M, Cole, D C, Kaur J S, Kerr K J. 2007. Cancer health effects of pesticides: Systematic review. Canadian Family Physician, 53, 1704–1711.

Belenky P, Jonathan D Y, Porter C B, Cohen N R, Lobritz M A, Ferrante T, Collins J J. 2015. Bactericidal antibiotics induce toxic metabolic perturbations that lead to cellular damage. Cell Report, 13, 968−980.

Bodet C, La V D, Gafner S, Bergeron C, Grenier D. 2008. A licorice extract reduces lipopolysaccharide-induced proinflammatory cytokine secretion by macrophages and whole blood. Journal of Periodontology, 79, 1752−1761.

Cai Y, Xu Y Q, Chan H F, Fang X B, He C W, Chen M W. 2016. Glycyrrhetinic acid mediated drug delivery carriers for hepatocellular carcinoma therapy. Molecular Pharmaceutics, 13, 699−709.

Chen H J, Kang S P, Lee I J, Lin Y L, 2014. Glycyrrhetinic acid suppressed NF-κB activation in TNF-α-induced hepatocytes. Journal of Agricultural and Food Chemistry, 62, 618–625.

Chen H M, Liu H Z, Tang B, Chen Y C, Han L, Yu J J, Yan Y H, Lu C J. 2020. The protective effects of 18β-glycyrrhetinic acid on imiquimod-induced psoriasis in mice via suppression of mTOR/STA-T3 signaling. Journal of Immunology Research, 2020, 1–9.

Diallinas G, Kanellis A K. 1994. A phenylalanine ammonia-lyase gene from melon fruit: cDNA cloning, sequence and expression in response to development and wounding. Plant Molecular Biology, 26, 473–479.

Dixon R A, Pavia N L. 1995. Stress-induced phenylpropanoid metabolism. Plant Cell, 7, 1085–1097.

He F C, Shi J, Wang Y J, Wang S B, Chen J X, Gan X H, Song B A, Hu D Y. 2019. Synthesis, antiviral activity, and mechanisms of purine nucleoside derivatives containing a sulfonamide moiety. Journal of Agricultural and Food Chemistry, 67, 8459–8467.

He S S, Lin Q, Qu M K, Wang L Y, Deng L, Xiao L Y, Zhang Z R, Zhang L. 2018. Liver-targeted co-delivery of entecavir and glycyrrhetinic acid based on albumin nanoparticle to enhance the accumulation of entecavir. Molecular Pharmaceutics, 15, 3953–3961.

Huang G L, Lv M J, Hu J C, Huang K L, Xu H. 2016. Glycosylation and activities of natural products. Mini-Reviews in Medicinal Chemistry, 16, 1013–1016.

Huang L R, Hao X J, Li Q J, Wang D P, Zhang J X, Luo H, Yang X S. 2016. 18β-Glycyrrhetinic acid derivatives possessing a trihydroxylated a ring are potent Gram-positive antibacterial agents. Journal of Natural Products, 79, 721–731.

Huang N, Angeles E R, Domingo J, Magpantay G, Singh S, Zhang G, Kumaravadivel N, Bennett J, Khush G S. 1997. Pyramiding of bacterial blight resistance genes in rice: Marker-assisted selection using RFLP and PCR. Theoretical and Applied Genetics, 95, 313–320.

Isbrucker R A, Burdock G A. 2006. Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin. Regulatory Toxicology and Pharmacology, 46, 167–192.

Iwai C B, Sujira H, Somparn A, Komarova T, Mueller J, Noller B. 2007. Monitoring pesticides in the paddy field ecosystem of north-eastern thailand for environmental and health risks. Rational Environmental Management of Agrochemicals, 996, 259–273.

Jiang S C, Su S J, Chen M, Peng F, Zhou Q, Liu T T, Liu L W, Xue W. 2020. Antibacterial activities of novel dithiocarbamate-containing 4H-Chromen-4-one derivatives. Journal of Agricultural and Food Chemistry, 68 , 5641–5647.

Kalaiarasi P, Pugalendi K.V. 2009. Antihyperglycemic effect of 18β-glycyrrhetinic acid, aglycone of glycyrrhizin, on streptozotocin-diabetic rats. European Journal of Pharmacology, 606, 269–273.

Khare E, Mishra J, Arora N K. 2018. Multifaceted interactions between endophytes and plant: Developments and prospects. Frontiers in Microbiology, 9, 2732.

Lawton M A, Lamb C J. 1987. Transcriptional activation of plant defense genes by fungal elicitor, wounding and infection. Molecular and Cellular Biology, 7, 335–341.

Li H W, Sun J Q, Xiao S L, Zhang L H, Zhou D M. 2020. Triterpenoid-mediated inhibition of virus–host interaction: Is now the time for discovering viral entry/release inhibitors from nature? Journal of Medicinal Chemistry, 63, 15371–15388.

Mansfield J, Genin S, Magori S, Citovsky V, Sriariyanum M, Ronald P, Dow M, Verdier V, Beer S V, Machado M A, Toth I, Salmond G, Foster G D. 2012. Top 10 plant pathogenic bacteria in molecular plant pathology. Molecular Plant Pathology, 13, 614–629.

Markov A V, Sen’kova A V, Popadyuk II, Salomatina O V, Logashenko E B, Komarova N I, Ilyina A A, Salakhutdinov N F, Zenkova M A. 2020. Novel 3’-substituted-1’,2’,4’-oxadiazole derivatives of 18βH-glycyrrhetinic acid and their o-acylated amidoximes: Synthesis and evaluation of antitumor and anti-inflammatory potential in vitro and in vivo. International Journal of Molecular Sciences, 21, 3511.

Molina-Torres J, Salazar-Cabrera C J, Armenta-Salinas C, Ramírez-Chávez E. 2004. Fungistatic and bacteriostatic activities of alkamides from Heliopsis longipes roots: Affinin and reduced amides. Journal of Agricultural and Food Chemistry, 52, 4700–4704.

Pan X Y, Xu S, Wu J, Luo J Y, Duan Y B, Wang J X, Zhang F, Zhou M G. 2018. Screening and characterization of Xanthomonas oryzae pv. oryzae strains with resistance to pheazine-1-carboxylic acid. Pesticide Biochemistry and Physiology, 145, 8–14.

Rigano L A, Siciliano F, Enrique R, Sendín L, Filippone P, Torres P S, Questa J, Dow J M, Castagnaro A P, Vojnov A A, Marano M R. 2007. Biofilm formation, epiphytic fitness, and canker development in Xanthomonas axonopodis pv. citri. Molecular Plant–Microbe Interactions, 20, 1222–1230.

Sanborn M, Kerr K J, Sanin L H, Cole D C, Bassil K L, Vakil C. 2007. Non-cancer health effects of pesticides: Systematic review and implications for family doctors. Canadian Family Physician, 53, 1712–1720.

Sanchez-Ballesta M T, Zacarias L, Granell A, Lafuente M T. 2000. Accumulation of PAL transcript and PAL activity as affected by heat-conditioning and low-temperature storage and its relation to chilling sensitivity in mandarin fruits. Journal of Agricultural and Food Chemistry, 48, 2726−2731.

Schmid C, Dawid C, Peters V, Hofmann T. 2018. Saponins from european licorice roots (Glycyrrhiza glabra). Journal of Natural Products, 81, 1734–1744.

Vida P, Moretto A. 2007. Pesticide exposure pathways among children of agricultural workers. Journal of Public Health, 15, 289–299.

Wang C Y, Kao T C, Lo W H, Yen G C. 2011. Glycyrrhizic acid and 18β-glycyrrhetinic acid modulate lipopolysaccharide-induced inflammatory response by suppression of NF-κB through PI3K p110δ and p110γ inhibitions. Journal of Agricultural and Food Chemistry, 59, 7726–7733.

Wang M W, Zhu H H, Wang P Y, Zeng D, Wu Y Y, Liu L W, Wu Z B, Li Z, Yang S. 2019. Synthesis of thiazolium-labeled 1, 3,4-oxadiazole thioethers as prospective antimicrobials: In vitro and in vivo bioactivity and mechanism of action. Journal of Agricultural and Food Chemistry, 67, 12696–12708.

Wang P Y, Xiang M, Luo M, Liu H W, Zhou X, Wu Z B, Liu L W, Li Z, Yang S. 2020. Novel piperazine-tailored ursolic acid hybrids as significant antibacterial agents targeting phytopathogens Xanthomonas oryzae pv. oryzae and X. axonopodis pv. citri probably directed by activation of apoptosis. Pest Management Science, 76, 2746–2754.

Wu C H, Chen A Z, Yen G C. 2015. Protective effects of glycyrrhizic acid and 18β-glycyrrhetinic acid against cisplatin-induced nephrotoxicity in BALB/c mice. Journal of Agricultural and Food Chemistry, 63, 1200–1209.

Xiang M, Song Y L, Ji J, Zhou X, Liu L W, Wang P Y, Wu Z B, Li Z, Yang S. 2020. Synthesis of novel 18β-glycyrrhetinic piperazine amides displaying significant in vitro and in vivo antibacterial activities against intractable plant bacterial diseases. Pest Management Science, 76, 2959–2971.

Xiang M, Zhou X, Luo T R, Wang P Y, Liu L W, Li Z, Wu Z B, Yang S. 2019. Design, synthesis, antibacterial evaluation, and induced apoptotic behaviors of epimeric and chiral 18β-glycyrrhetinic acid ester derivatives with an isopropanolamine bridge against phytopathogens. Journal of Agricultural and Food Chemistry, 67, 13212–13220.

Xu Y, Zhu X F, Zhou M G, Kuang J, Zhang Y, Shang Y, Wang J X. 2010. Status of streptomycin resistance development in Xanthomonas oryzae pv. oryzae and Xanthomonas oryzae pv. oryzicola in China and their resistance characters. Journal of Phytopathology, 158, 601–608.

Yamaguchi H, Kidachi Y, Kamiie K, Noshita T, Umetsu H. 2012. Structural insight into the ligand-receptor interaction between glycyrrhetinic acid (GA) and the high-mobility group protein B1 (HMGB1)-DNA complex. Bioinformation, 8, 1147–1153.

Yang D Y, Zhao B, Fan Z J, Yu B, Zhang N, Li Z, Zhu Y, Zhou J, Kalinina T A, Glukhareva T V. 2019. Synthesis and biological activity of novel succinate dehydrogenase inhibitor derivatives as potent fungicide candidates. Journal of Agricultural and Food Chemistry, 67, 13185–13194.

Yang T, Zhang T, Zhou X, Wang P Y, Gan J, Song B A, Yang S, Yang C. G. 2021. Dysregulation of ClpP by small-molecule activators used against Xanthomonas oryzae pv. oryzae infections. Journal of Agricultural and Food Chemistry, 69, 7545–7553.

Yang Y, Zhu Q Y, Zhong Y Y, Cui X P, Jiang Z Y, Wu P P, Zheng X, Zhang K, Zhao S Q. 2020. Synthesis, anti-microbial and anti-inflammatory activities of 18β-glycyrrhetinic acid derivatives. Bioorganic Chemistry, 101, 103985.

Yoon J K, Cao X D, Zhou Q X, Ma L Q. 2006. Accumulation of Pb, Cu, and Zn in native plants growing on a contaminated Florida site. Science of the Total Environment, 368, 456–464.

Zhou X, Feng Y M, Qi P Y, Shao W B, Wu Z B, Liu L W, Wang Y, Ma H D, Wang P Y, Li Z, Yang S. 2020. Synthesis and docking study of N-(Cinnamoyl)-N´-(substituted) acryloyl hydrazide derivatives containing pyridinium moieties as a novel class of filamentous temperature-sensitive protein Z inhibitors against the intractable Xanthomonas oryzae pv. oryzae infections in rice. Journal of Agricultural and Food Chemistry, 68, 8132–8142.

Zhou X, Ye H J, Gao X H, Feng Y M, Shao W B, Qi P Y, Wu Z B, Liu L W, Wang P Y, Yang S. 2021. The discovery of natural 4’-demethylepipodophyllotoxin from renewable Dysosma versipellis species as a novel bacterial cell division inhibitor for controlling intractable diseases in rice. Industrial Crops and Products, 174, 114182.

Zhou X Z, Zhao L, Liu X M, Li X Q, Jia F, Zhang Y Y, Wang, Y J. 2012. Antimycobacterial and synergistic effects of 18β-glycyrrhetinic acid or glycyrrhetinic acid-30-piperazine in combination with isoniazid, rifampicin or streptomycin against Mycobacterium bovis. Phytotherapy Research, 26, 253–258.

Zhu X F, Xu Y, Peng D, Zhang Y, Huang T T, Wang J X, Zhou M G. 2013. Detection and characterization of bismerthiazol-resistance of Xanthomonas oryzae pv. oryzae. Crop Protection, 47, 24–29.

Zígolo M A, Salinas M, Alché L, Baldessari A, Liñares G G. 2018. Chemoenzymatic synthesis of new derivatives of glycyrrhetinic acid with antiviral activity. Molecular docking study. Bioorganic Chemistry, 78, 210–219.