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Journal of Integrative Agriculture  2020, Vol. 19 Issue (11): 2775-2783    DOI: 10.1016/S2095-3119(20)63302-0
Special Issue: 动物营养合辑Animal Nutrition
Animal Science · Veterinary Medicine Advanced Online Publication | Current Issue | Archive | Adv Search |
Effect of dietary calcium or phosphorus deficiency on bone development and related calcium or phosphorus metabolic utilization parameters of broilers from 22 to 42 days of age
YANG Yun-feng1*, XING Guan-zhong1, 3*, LI Su-fen3, SHAO Yu-xin1, ZHANG Li-yang1, LU Lin1, LUO Xu-gang2, LIAO Xiu-dong1 
1 Mineral Nutrition Research Division, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.China
2 Poultry Mineral Nutrition Laboratory, College of Animal Science and Technology, Yangzhou University, Yangzhou 225000, P.R.China
3 College of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, P.R.China
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Abstract  
This experiment was conducted to investigate the effect of dietary calcium (Ca) or phosphorus (P) deficiency on bone development and related Ca or P metabolic utilization parameters of broilers from 22 to 42 days of age based on our previous study, which indicated that dietary Ca or P deficiency impaired the bone development by regulating related Ca or P metabolic utilization parameters of broilers from 1 to 21 days of age.  A total of 504 one-day-old Arbor Acres male broilers were randomly assigned to 1 of 4 treatments with 7 replicates in a completely randomized design, and fed the normal control and Ca- or P-deficient diets from 1 to 21 days of age.  At 22 days of age, the broilers were further fed the normal control diet (0.90% Ca+0.35% non-phytate P (NPP)), the P-deficient diet (0.90% Ca+0.18% NPP), the Ca-deficient diet (0.30% Ca+0.35% NPP) or the Ca and P-deficient diet (0.30% Ca+0.18% NPP), respectively.  The results showed that dietary Ca or P deficiency decreased (P<0.05) tibia bone mineral density (BMD), bone breaking strength (BBS), ash content, tibia ash Ca content and serum P content on days 28 and 42, but increased (P<0.05) tibia alkaline phosphatase (ALP) activity of broilers on day 42 compared with the control group.  Furthermore, the broilers fed the P-deficient diet had the lowest (P<0.05) tibia BMD, BBS, ash content, serum P content and the highest (P<0.05) serum Ca content on day 28 compared with those fed the Ca-deficient or Ca and P-deficient diets.  The results from the present study indicated that the bone development and related Ca or P metabolic utilization parameters of broilers were the most sensitive to dietary P deficiency, followed by dietary Ca deficiency or Ca and P-deficiency; dietary Ca or P deficiency impaired the bone development possibly by regulating serum Ca and P contents as well as tibia Ca content and ALP activity of broilers from 22 to 42 days of age.
Keywords:  calcium deficiency        phosphorus deficiency        bone development        metabolic utilization parameter        broiler  
Received: 13 November 2019   Accepted:
Fund: The present study was financially supported by the National Key R&D Program of China (2017YF0502200), the Key Program of the National Natural Science Foundation of China (31630073), the earmarked fund for China Agriculture Research System (CARS-41), the Agricultural Science and Technology Innovation Program, China (ASTIP-IAS09), and the earmarked fund for Hebei Chicken Innovation Team of Modern Agro-Industry Technology Research System, China (HBCT2018150203 and HBCT2018150206).
Corresponding Authors:  Correspondence LUO Xu-gang, E-mail: wlysz@263.net; LIAO Xiu-dong, E-mail: liaoxd56@163.com    
About author:  YANG Yun-feng, E-mail: 604345120@163.com; * These authors contributed equally to this study.

Cite this article: 

YANG Yun-feng, XING Guan-zhong, LI su-fen, SHAO Yu-xin, ZHANG Li-yang, LU Lin, LUO Xu-gang, LIAO Xiu-dong. 2020. Effect of dietary calcium or phosphorus deficiency on bone development and related calcium or phosphorus metabolic utilization parameters of broilers from 22 to 42 days of age. Journal of Integrative Agriculture, 19(11): 2775-2783.

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