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| Toxicological Evaluation of Chicken-Breast Meat with High-Dose Irradiation |
| ZHU Jia-ting, FENG Min, YAN Jian-min, LIU Chun-quan, HA Yi-ming, GAO Mei-xu, YANG Ping, WANG Zhi-dong, WANG De-ning, LI Shu-rong, GU Gui-qiang |
1.Institute of Atomic Energy in Application for Agriculture, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, P.R.China
2.Institute of Farm Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, P.R.China
3.Institute of Agro-Products Processing Science&Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.China |
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摘要 In this paper, toxicity and safety of high-dose irradiated chicken-breast meat were evaluated. For assays of acute toxicity, genetic toxicity, and sub-chronic toxicity, ames test, mice bone marrow erythrocyte micronucleus, and mice sperm abnormality were performed. The results showed that, in the acute oral toxicity tests, median lethal dose (more than 10 000 mg kg-1) in male and female ICR mice showed no toxicological signs. For subacute 30-d oral toxicology of irradiated chicken-breast meat with dose of 10, 15 and 25 kGy in both male and female SD rats, no noticeable toxicological effects were observed. It is concluded that chicken-breast meat with high-dose irradiation has no acute toxicity and no genotoxicity, nor harmful effects on the animal body at the tested dosage range. Therefore, high-dose irradiated chicken-breast meat is safe for pet consumption.
Abstract In this paper, toxicity and safety of high-dose irradiated chicken-breast meat were evaluated. For assays of acute toxicity, genetic toxicity, and sub-chronic toxicity, ames test, mice bone marrow erythrocyte micronucleus, and mice sperm abnormality were performed. The results showed that, in the acute oral toxicity tests, median lethal dose (more than 10 000 mg kg-1) in male and female ICR mice showed no toxicological signs. For subacute 30-d oral toxicology of irradiated chicken-breast meat with dose of 10, 15 and 25 kGy in both male and female SD rats, no noticeable toxicological effects were observed. It is concluded that chicken-breast meat with high-dose irradiation has no acute toxicity and no genotoxicity, nor harmful effects on the animal body at the tested dosage range. Therefore, high-dose irradiated chicken-breast meat is safe for pet consumption.
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Received: 10 November 2011
Accepted:
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| Fund: This work was supported by the Special Fund for Agro- Scientific Research in the Public Interest, China (201103007). |
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Corresponding Authors:
Correspondence ZHU Jia-ting, Tel/Fax: +86-25-84391942, E-mail: zjtlw@163.com
E-mail: zjtlw@163.com
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Cite this article:
ZHU Jia-ting, FENG Min, YAN Jian-min, LIU Chun-quan, HA Yi-ming, GAO Mei-xu, YANG Ping, WANG Zhi-dong, WANG De-ning, LI Shu-rong, GU Gui-qiang.
2012.
Toxicological Evaluation of Chicken-Breast Meat with High-Dose Irradiation. Journal of Integrative Agriculture, 12(12): 2088-2096.
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