中国农业科学 ›› 2008, Vol. 41 ›› Issue (5): 1255-1266 .doi: 10.3864/j.issn.0578-1752.2008.05.001

• 作物遗传育种·种质资源·分子遗传学 •    下一篇

复杂性状遗传分析策略和方法研究进展

汤在祥,徐辰武   

  1. 扬州大学江苏省作物遗传生理重点实验室/教育部植物功能基因组学重点实验室
  • 收稿日期:2007-01-23 修回日期:2007-05-28 出版日期:2008-05-10 发布日期:2008-05-10
  • 通讯作者: 徐辰武

In search of Genetic Architecture of Complex Traits

  

  1. 扬州大学江苏省作物遗传生理重点实验室/教育部植物功能基因组学重点实验室
  • Received:2007-01-23 Revised:2007-05-28 Online:2008-05-10 Published:2008-05-10

摘要: 复杂性状是指由多基因和非遗传因素共同作用的一类性状的总称,包括表型呈连续分布的经典数量性状,多基因控制但表型呈间断分布的二歧或多歧性状,以及难以准确度量的动物各种行为性状等。动植物的许多重要经济性状以及人类复杂疾病均属于复杂性状范畴。阐明复杂性状的遗传基础,对于动植物新品种的遗传改良具有十分重要的意义。本文在阐述复杂性状基本概念的基础上,综述了复杂性状的遗传分析策略以及近年来取得的主要研究进展。最后,对后基因组时代复杂性状基础研究面临的挑战提出了一些讨论,以供参考。

关键词: 复杂性状, 遗传基础, 遗传资源, 数量性状

Abstract: Complex traits are features whose properties are determined by multiple factors ,which can be genetic or environmental, and whose inheritance does not follow the simple rules of Mendelian genetics. Most human complex diseases and most economically important traits in plants and animals are complex traits. The molecular basis of complex traits is theoretical and applied important for genetic improvement in plant and animal breeding. We summarized the conception and research background of complex traits and reviewed the strategies identifying genes underlying complex traits. Based on these strategies, the great progress had been made in dissecting genetic basis of complex traits. At last, we also discussed the challenges and possible developments in future research.

Key words: Complex trait, Genetic basis, Genetic resource, Quantitative trait