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Journal of Integrative Agriculture  2019, Vol. 18 Issue (9): 2093-2106    DOI: 10.1016/S2095-3119(19)62565-7
Special Issue: 线虫合辑Nematology
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The synergistic advantage of combining chloropicrin or dazomet with fosthiazate nematicide to control root-knot nematode in cucumber production
HUANG Bin1, WANG Qian1, GUO Mei-xia1, 2, FANG Wen-sheng1, WANG Xiao-ning1, WANG Qiu-xia1, 2, YAN Dong-dong1, 2, OUYANG Can-bin1, 2, LI Yuan1, 2, CAO Ao-cheng1, 2
1 Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, P.R.China
2 Beijing Innovation Consortium of Agriculture Research System, Beijing 100193, P.R.China
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The highly-damaging root-knot nematode (Meloidogyne spp., RKN) cannot be reliably controlled using only a nematicide such as fosthiazate because of increasing pest resistance.  In laboratory and greenhouse trials, we showed that chloropicrin (CP) or dazomet (DZ) synergized the efficacy of fosthiazate against RKN.  The combination significantly extended the degradation half-life of fosthiazate by an average of about 1.25 times.  CP or DZ with fosthiazate reduced the time for fosthiazate to penetrate the RKN cuticle compared to fosthiazate alone.  CP or DZ combined with low or medium rate of fosthiazate increased the total cucumber yield, compared to the use of each product alone.  A low-dose fosthiazate with DZ improved total yield more than a low dose fosthiazate with CP.  Extending the half-life of fosthiazate and reducing the time for fosthiazate or fumigant to penetrate the RKN cuticle were the two features that gave the fumigant-fosthiazate combination its synergistic advantage over these products used singularly.  This synergy provides the opportunity for farmers to use a low dose of fosthiazate which lowers the risk of RKN resistance.  Farmers could combine DZ at 30 g m–2 with fosthiazate at a low rate of 0.375 g m–2 to control RKN and adequately control two major soil-borne diseases in cucumber greenhouses.
Keywords:  dazomet        chloropicrin        fosthiazate        cucumber        root-knot nematode  
Received: 25 July 2018   Accepted:
Fund: The authors are grateful for the financial support from the Key Research and Development Program of China (2017YFD0201600), the National Natural Science Foundation of China (31672066), the China Scholarship Council (201704280020) and the Agricultural Science and Technology Innovation Program of China over the years.
Corresponding Authors:  Correspondence Cao Ao-cheng, Tel: +86-10-62815940, Fax: +86-10-62894863, E-mail:   
About author:  HUANG Bin, E-mail:;

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HUANG Bin, WANG Qian, GUO Mei-xia, FANG Wen-sheng, WANG Xiao-ning, WANG Qiu-xia, YAN Dong-dong, OUYANG Can-bin, LI Yuan, CAO Ao-cheng. 2019. The synergistic advantage of combining chloropicrin or dazomet with fosthiazate nematicide to control root-knot nematode in cucumber production. Journal of Integrative Agriculture, 18(9): 2093-2106.

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