中国农业科学 ›› 2023, Vol. 56 ›› Issue (13): 2431-2442.doi: 10.3864/j.issn.0578-1752.2023.13.001

• 作物遗传育种·种质资源·分子遗传学 • 上一篇    下一篇

小麦类黄酮的遗传基础与功能性小麦育种应用

陈杰(), 陈伟   

  1. 华中农业大学植物科学技术学院/作物遗传改良全国重点实验室,武汉 430070
  • 收稿日期:2023-03-29 接受日期:2023-05-10 出版日期:2023-07-01 发布日期:2023-07-06
  • 通信作者:
    陈杰,E-mail:
  • 基金资助:
    国家自然科学基金(32001541); 中国博士后科学基金(2021T140246)

The Genetic Basis of Flavonoid Contents in Wheat and Its Application in Functional Wheat Variety Breeding

CHEN Jie(), CHEN Wei   

  1. College of Plant Science and Technology, Huazhong Agricultural University/National Key Laboratory of Crop Genetics and Improvement, Wuhan 430070
  • Received:2023-03-29 Accepted:2023-05-10 Published:2023-07-01 Online:2023-07-06

摘要:

随着人们生活水平的提高,对食物的要求逐渐由“吃饱”向“吃好”以及“吃入营养”“吃出健康”等方向转变。小麦是我国以及世界最重要的粮食作物之一,育种家们认为小麦育种也要从“产量育种”向“品质育种”转变,即产量基本不变的前提下使得小麦籽粒具有特定有益人体健康的“功能性”成分,这些成分一般是小分子代谢物。与之相对应,还进一步提出了“功能性小麦品种”的概念。黄酮类代谢物是目前受到广泛关注的一类物质,由于它能够影响植株表型以及人类健康,该类物质含量也是“功能性小麦”育种的范畴之一。为了更好地促进“功能性小麦”育种,需要使用多种手段解析影响特定“功能性”代谢物含量的分子机理和遗传基础。代谢组学手段与遗传学设计相结合能够高效鉴定影响代谢物含量的基因,然而由于小麦参考基因组信息公布较晚,小麦中这类研究进展相对滞后,导致对于代谢物的遗传基础揭示不足,从而限制其在“功能性小麦”育种中的应用。本文以黄酮类物质为例,概述了解析这类代谢物遗传基础的研究进展,相关研究结果将为以提高黄酮类物质含量为主要目标的“功能性小麦”育种提供分子资源和理论基础,以及为研究其他“功能性”代谢物提供借鉴。与此同时,还初步构想了在相关基础研究积累不足的前提下直接使用代谢组学手段辅助育种的方式,有望在获得育种中间材料的同时“顺便”解析关键遗传因子或者候选基因,从而有效推动“功能性小麦”育种。

关键词: 黄酮, 功能性小麦, 遗传基础, 育种

Abstract:

Accompanying the elevated expenses on consumption, people’s urge upon food has been gradually changed from “eat to be fed” to “eat to be satisfied” and further to “eat to gain nutrition” and “eat to be healthy”. Accordingly, breeders considered the wheat breeding goals should be set as breeding wheat with better quality along with higher yield, wherein the phrase “functional wheat variety” was recently raised. Flavonoids comprise one of the most widely reported categories of metabolites, the contents of which have been included within the “functional wheat variety” breeding program for its connection with plant phenotypes and its contribution to human health. The combination of metabolomics approach and genetics design has been proved to be efficient in identifying the candidates that responsible for metabolite contents, that said its application in wheat was lagged behind due to the lately released wheat reference genome. Further, the deficient knowledge upon the genetic basis of metabolites has in turn constrained the application of breeding “functional wheat variety”. In the current manuscript, the research progresses on genetic basis of flavonoids are briefly summarized, and its application for wheat breeding is highlighted. Meanwhile, the metabolomics-assisted breeding frame is concepted. Ultimately, the “functional wheat variety” breeding program will be achieved through the combination of the fundamental researches and breeding applications.

Key words: flavonoid, functional wheat, genetic basis, breeding