中国农业科学 ›› 2010, Vol. 43 ›› Issue (9): 1761-1770 .doi: 10.3864/j.issn.0578-1752.2010.09.001

• 作物遗传育种·种质资源·分子遗传学 •    下一篇

提高转基因植物标记基因安全性策略的研究进展

李文凤,季静,王罡,王海勇,牛宝龙

  

  1. (天津大学农业与生物工程学院)
  • 收稿日期:2009-11-02 修回日期:2009-12-21 出版日期:2010-05-01 发布日期:2010-05-01
  • 通讯作者: 季静

Strategies on the Safety of Selectable Marker Genes in Transgenic Plant

LI Wen-feng, JI Jing, WANG Gang, WANG Hai-yong, NIU Bao-long
  

  1. (天津大学农业与生物工程学院)
  • Received:2009-11-02 Revised:2009-12-21 Online:2010-05-01 Published:2010-05-01
  • Contact: JI Jing

摘要:

目前,广泛使用的转基因植物抗性标记基因对环境和食品存在潜在风险。提高转基因植物标记基因安全性策略有3种:利用无争议的生物安全标记基因;剔除转基因植物中选择标记基因;利用无选择标记基因的转化系统。本文综述了这3种策略的作用原理、种类和存在的问题,并对提高转基因标记基因安全性技术途径的前景和研究方向进行了分析。

关键词: 选择标记基因, 转基因植物, 生物安全性

Abstract:

Selectable marker genes encoding antibiotic and herbicide are widely used in transgenic plants and have a potential risk to the environment and human health. Currently, there are three kinds of strategies to improve security in using marker genes in transgenic plants: One approach is to develop the use of uncontested biosafety marker genes, the second is to use transgenic plants-removed selectable marker genes and the third is the use of non-selective marker gene transformation system. In this review, each of the strategy principles and problems are highlighted. Moreover, the perspectives are discussed to improve the safety of selectable marker genes in transgenic plants.

Key words: selectable marker genes, transgenic plant, bio-safety