中国农业科学 ›› 2010, Vol. 43 ›› Issue (23): 4917-4927 .doi: 10.3864/j.issn.0578-1752.2010.23.018

• 畜牧·资源昆虫 • 上一篇    下一篇

中国主要地方绵羊品种遗传共适应的检测及其与近缘物种山羊的比较

孙伟,常洪,杨章平,马月辉,关伟军,储明星,角田健司,吴文忠,陈玲,钱建共

  

  1. (扬州大学动物科学与技术学院)
  • 收稿日期:2010-07-15 修回日期:2010-11-01 出版日期:2010-12-01 发布日期:2010-12-01

Detection of Genetic Co-Adaptability of Chinese Local Sheep Breeds and Comparison with Their Closely Related Species-Goat

SUN Wei, CHANG Hong, YANG Zhang-ping, MA Yue-hui, GUAN Wei-jun, CHU Ming-xing,TSUNODA Ken-ji, WU Wen-zhong, CHEN Ling, QIAN Jian-gong
  

  1. (扬州大学动物科学与技术学院)
  • Received:2010-07-15 Revised:2010-11-01 Online:2010-12-01 Published:2010-12-01

摘要:

【目的】探讨用于遗传共适应分析的合适组合座位模型,为遗传共适应理论增添关于绵羊品种间及与近缘物种山羊间遗传共适应进化机制差异比较的研究内容。【方法】以中国主要地方绵羊品种湖羊、同羊、小尾寒羊、滩羊和洼地绵羊为研究对象,以近缘物种山羊作为对照群体,选择多态程度不同的9个结构基因座。【结果】(1)“显隐性-显隐性”模型不适合遗传共适应的分析;“共显性-显隐性”和“共显性-共显性”模型可用于遗传共适应的分析。(2)对于与具有过多稀有等位基因的Tf座位组合的座位间的遗传不平衡的原因,经典的中性遗传不平衡原理并不能给出合理的解释或解释的原因前后不一致。(3)不同物种、不同品种的遗传共适应系数、遗传不平衡系数以及连锁不平衡系数与座位的组合有关。【结论】(1)在“显隐性-显隐性”组合不存在遗传共适应现象,而在“共显性-显隐性”模型和“共显性-共显性”模型中有可能发现存在遗传共适应现象。(2)由于起源不同,绵羊与山羊间遗传共适应存在较大差异,而绵羊物种内不同品种间由于起源相同,在遗传共适应上差异不大,有趋向一致的倾向。(3)本文首次拟合得到的不同座位组合模型的遗传共适应系数与遗传不平衡系数的回归方程,对于探讨遗传共适应的作用机理与计算具有一定的借鉴意义。

关键词: 结构基因座, 遗传共适应性, 绵羊品种, 近缘物种

Abstract:

【Objective】The objective of this study was to find the proper model of combined loci in analysis of genetic co-adaptability, and add the data of genetic co-adaptability theory on evolution mechanism difference of genetic co-adaptability among breeds or between closely related species-goat.【Method】Tan sheep, small-tailed Han sheep, Hu sheep, Tong sheep and Wadi sheep were regarded as the research objects and their closely related species-goat was served as the reference object, and 9 structural loci with different polymorphism were selected. 【Result】 The dominant-dominant model was not proper to be used in genetic co-adaptability analysis. The co-dominant-dominant model the co-dominant-co-dominant model could be used in genetic co-adaptability analysis. The principles of classic neutral gene genetic disequilibrium could explain most genetic disequilibrium between loci, but the principles could not fit for Tf locus with too many rare alleles, because it could not provide a rational explanation or the explanation was inconsistent. The differences in the coefficients of genetic co-adaptability, genetic disequilibrium and link disequilibrium between sheep and goat (among species) and breeds (within groups) decided by different loci combinations. 【Conclusion】 Genetic co-adaptability do not exist in the loci combination of dominant-dominant, but it may exist in the loci combination of co-dominant-dominant and co-dominant-co-dominant. Due to different origins, there is a large difference in genetic co-adaptability between sheep and goat, while the different breeds of sheep species with the same origin have a consistent tendency in genetic co-adaptability. This is the first time, that the regression equations of coefficients of genetic co-adaptability and genetic disequilibrium in different models were obtained, which will be helpful for research on function mechanism and calculation of genetic co-adaptability.

Key words: structural loci, genetic co-adaptability, sheep breeds, closed related