Journal of Integrative Agriculture ›› 2015, Vol. 14 ›› Issue (11): 2282-2295.DOI: 10.1016/S2095-3119(15)61121-2
XU Fei, REN Kang, YANG Yu-ze, GUO Jiang-peng, MA Guang-peng, LIU Yi-ming, LU Yong-qiang, LI Xiu-bo
收稿日期:
2015-04-16
出版日期:
2015-11-08
发布日期:
2015-11-12
通讯作者:
LI Xiu-bo,Tel: +86-10-82106059, E-mail: lixiubo@caas.cn; LU Yong-qiang,Tel: +86-10-84929001, E-mail: luyongqiang@163.com
作者简介:
XU Fei, E-mail: xufei@caas.cn;
基金资助:
This work was financially supported by the Beijing Dairy Industry Innovation Team and Feed Quality and Safety Control Innovation Team of Chinese Academy of Agricultural Sciences.
XU Fei, REN Kang, YANG Yu-ze, GUO Jiang-peng, MA Guang-peng, LIU Yi-ming, LU Yong-qiang, LI Xiu-bo
Received:
2015-04-16
Online:
2015-11-08
Published:
2015-11-12
Contact:
LI Xiu-bo,Tel: +86-10-82106059, E-mail: lixiubo@caas.cn; LU Yong-qiang,Tel: +86-10-84929001, E-mail: luyongqiang@163.com
About author:
XU Fei, E-mail: xufei@caas.cn;
Supported by:
This work was financially supported by the Beijing Dairy Industry Innovation Team and Feed Quality and Safety Control Innovation Team of Chinese Academy of Agricultural Sciences.
摘要: The detection of chemical contaminants is critical to ensure dairy safety. These contaminants include veterinary medicines, antibiotics, pesticides, heavy metals, mycotoxins, and persistent organic pollutants (POPs). Immunoassays have recently been used to detect contaminants in milk because of their simple operation, high speed, and low cost. This article describes the latest developments in the most important component of immunoassays — antibodies, and then reviews the four major substrates used for immunoassays (i.e., microplates, membranes, gels, and chips) as well as their use in the detection of milk contaminants. The paper concludes with prospects for further applications of these immunoassays.
XU Fei, REN Kang, YANG Yu-ze, GUO Jiang-peng, MA Guang-peng, LIU Yi-ming, LU Yong-qiang, LI Xiu-bo. Immunoassay of chemical contaminants in milk: A review[J]. Journal of Integrative Agriculture, 2015, 14(11): 2282-2295.
XU Fei, REN Kang, YANG Yu-ze, GUO Jiang-peng, MA Guang-peng, LIU Yi-ming, LU Yong-qiang, LI Xiu-bo. Immunoassay of chemical contaminants in milk: A review[J]. Journal of Integrative Agriculture, 2015, 14(11): 2282-2295.
Ahmad Z A, Yeap S K, Ali A M, Ho W Y, Alitheen N B M, HamidM. 2012. ScFv antibody: Principles and clinical application.Clinical and Developmental Immunology, 2012, 1-15Alexiadou D K, Maragou N C, Thomaidis N S, Theodoridis GA, Koupparis M A. 2008. Molecularly imprinted polymersfor bisphenol A for HPLC and SPE from water and milk.Journal of Separation Science, 31, 2272-2282Anfossi L, Di Nardo F, Giovannoli C, Passini C, Baggiani C.2013. Increased sensitivity of lateral flow immunoassay forochratoxin A through silver enhancement. Analytical andBioanalytical Chemistry, 405, 9859-9867Barchanska H, Jodo E, Price R G, Baranowska I, AbukneshaR. 2012. Monitoring of atrazine in milk using a rapid tubebasedELISA and validation with HPLC. Chemosphere,87, 1330-1334Beloglazova N V, De Boevre M, Goryacheva I Y, WerbrouckS, Guo Y, De Saeger S. 2013. Immunochemical approachfor zearalenone-4-glucoside determination. Talanta, 106,422-430Beloglazova N V, Goryacheva I Y, Rusanova T Y, YurasovN A, Galve R, Marco M P, De Saeger S. 2010. Gelbasedimmunotest for simultaneous detection of2,4,6-trichlorophenol and ochratoxin A in red wine. AnalyticaChimica Acta, 672, 3-8Beloglazova N V, Goryacheva I Y, de Saeger S, Scippo M L,Niessner R, Knopp D. 2011. New approach to quantitativeanalysis of benzo[a]pyrene in food supplements by animmunochemical column test. Talanta, 85, 151-156Beltrán M C, Borràs M, Nagel O, Althaus R L, Molina M P. 2014.Validation of receptor-binding assays to detect antibioticsin goat’s milk. Journal of Food Protection, 77, 308-313Berlina A N, Taranova N A, Zherdev A V, Vengerov Y Y,Dzantiev B B. 2013. Quantum dot-based lateral flowimmunoassay for detection of chloramphenicol in milk.Analytical and Bioanalytical Chemistry, 405, 4997-5000Bian S M, Chu X G, Jin Y, Xing S G, Zhang Y, Hu HB. 2013. A novel microsphere-based fluorescenceimmunochromatographic assay for monitoring cefalexinresidues in plasma, milk, muscle and liver. AnalyticalMethods, 5, 6441-6448Bienenmann-Ploum M E, Huet A C, Campbell K, Fodey T L,Vincent U, Haasnoot W, Delahaut P, Elliott C, Nielen M,Schilt R. 2012. Fiveplex flow cytometric immunoassay forthe simultaneous detection of six coccidiostats in feed andeggs. Conference poster. In: Residues of Veterinary Drugsin Food. Proceedings of the EuroResidue VII Conference.14-16 May, 2012 Volume 1, 2 and 3. Egmond Aan Zee,Netherlands. pp. 899-902Bla?ková M, Mi?ková-Holubová B, Rauch P, Fukal L. 2009.Immunochromatographic colloidal carbon-based assay fordetection of methiocarb in surface water. Biosensors andBioelectronics, 25, 753-758Bu D, Zhuang H, Yang G, Ping X. 2014. An immunosensordesigned for polybrominated biphenyl detection based onfluorescence resonance energy transfer (FRET) betweencarbon dots and gold nanoparticles. Sensors and Actuators(B: Chemical), 195, 540-548Charest Morin X, Fortin J P, Bawolak M T, Lodge R, MarceauF. 2013. Green fluorescent protein fused to peptide agonistsof two dissimilar G protein-coupled receptors: Novelligands of the bradykinin B2 (rhodopsin family) receptorand parathyroid hormone PTH1 (secretin family) receptor.Pharmacology Research & Perspectives, 1, 1-13Charm. 2015. Charm II antiboitics kit. [2015-03-15]. http://www.charm.com/productsChen J, Xu F, Jiang H, Hou Y, Rao Q, Guo P, Ding S. 2009. Anovel quantum dot-based fluoroimmunoassay method fordetection of Enrofloxacin residue in chicken muscle tissue. Food Chemistry, 113, 1197-1201Chen L, Wang Z, Ferreri M, Su J, Han B. 2009. Cephalexinresidue detection in milk and beef by ELISA and colloidalgold based one-step strip assay. Journal of Agricultural andFood Chemistry, 57, 4674-4679Chen M, Wen K, Tao X Q, Ding S Y, Xie J, Yu X Z, Li JC, Xia X, Wang Y, Xie S L, Jiang H Y. 2014. A novelmultiplexed fluorescence polarisation immunoassaybased on a recombinant bi-specific single-chain diabodyfor simultaneous detection of fluoroquinolones andsulfonamides in milk. Food Additives and Contaminants(Part A-Chemistry Analysis Control Exposure & RiskAssessment), 31, 1959-1967Chen M, Wen K, Tao X Q, Xie J, Wang L M, Li Y, Ding S Y,Jiang H Y. 2014. Cloning, expression, purification andcharacterization of a bispecific single-chain diabody againstfluoroquinolones and sulfonamides in Escherichia coli.Protein Expression and Purification, 100, 19-25Chen R, Li H, Zhang H, Zhang S X, Shi W M, Shen J Z, WangZ H. 2013. Development of a lateral flow fluorescentmicrosphere immunoassay for the determination ofsulfamethazine in milk. Analytical and BioanalyticalChemistry, 405, 6783-6789Christie M, Boland A, Huntzinger E, Weichenrieder O, IzaurraldeE. 2013. Structure of the PAN3 pseudokinase reveals thebasis for interactions with the PAN2 deadenylase and theGW182 proteins. Molecular Cell, 51, 360-373Chung C H, Kim J H, Jung J, Chung B H. 2013. NucleaseresistantDNA aptamer on gold nanoparticles for thesimultaneous detection of Pb2+ and Hg2+ in human serum.Biosensors and Bioelectronics, 41, 827-832Council Regulation (EU). 2010. Council Regulation (EU) N37/2010, on Pharmacologically Active Substances andTheir Classification Regarding Maximum Residue Limitsin Foodstuffs of Animal Origin. pp. 1-72Van Dorst B, Mehta J, Rouah Martin E, Backeljau J, De CoenW, Eeckhout D, De Jaeger G, Blust R, Robbens J. 2012.Selection of scFv phages specific for chloramphenicolacetyl transferase (CAT), as alternatives for antibodies inCAT detection assays. Journal of Applied Toxicology, 32,783-789Edupuganti S R, Edupuganti O P, O’Kennedy R. 2013.Generation of anti-zearalenone scFv and its incorporationinto surface plasmon resonance-based assay for thedetection of zearalenone in sorghum. Food Control, 34,668-674Erdem A, Congur G. 2014. Voltammetric aptasensor combinedwith magnetic beads assay developed for detection ofhuman activated protein C. Talanta, 128, 428-433Feng H Y, Tong X, Li W L, Zhou L P, Shi L, Cai Q Y. 2014.Indirect competitive enzyme-linked immunosorbent assayof tris-(2,3-dibromopropyl) isocyanurate with monoclonalantibody. Talanta, 128, 434-444Feng L, Zhang Z, Ren J, Qu X. 2014. Functionalized grapheneas sensitive electrochemical label in target-dependentlinkage of split aptasensor for dual detection. Biosensorsand Bioelectronics, 62, 52-58Freitas S, Paim A, Silva P. 2014. Development of a LC-ITTOFMS procedure to quantify veterinary drug residues inmilk employing a QuEChERS approach. Food AnalyticalMethods, 7, 39-46Gao C, Wang Q, Gao F, Gao F. 2014. A high-performanceaptasensor for mercury(ii) based on the formation of aunique ternary structure of aptamer-Hg2+-neutral red.Chemical Communications, 50, 9397-9400Garcia-Fernandez J, Trapiella-Alfonso L, Costa-Fernandez JM, Pereiro R, Sanz-Medel A. 2014. A quantum dot-basedimmunoassay for screening of tetracyclines in bovinemuscle. Journal of Agricultural and Food Chemistry, 62,1733-1740Gomes F B M B, Riedstra S, Ferreira J P M. 2010. Developmentof an immunoassay for ciprofloxacin based on phagedisplayedantibody fragments. Journal of ImmunologicalMethods, 358, 17-22Gong Y F, Zhang M Z, Wang M Z, Chen Z L, Xi X. 2014.Development of immuno-based methods for detection ofmelamine. Arabian Journal for Science and Engineering,39, 5315-5324Goryacheva I Y, Beloglazova N V, Eremin S A, Mikhirev D A,Niessner R, Knopp D. 2008. Gel-based immunoassay fornon-instrumental detection of pyrene in water samples.Talanta, 75, 517-522Goryacheva I Y, Lenain P, De Saeger S. 2013. Nanosizedlabels for rapid immunotests. TrAC Trends in AnalyticalChemistry, 46, 30-43Granier B, Lepage S. 2011. Kit For Use in Detection ofComprising Nuclear Receptor for Use in the Detection andMeasurement of Tetracyclines and Virginiamycins. GooglePatents. US 7935806 B2.Griffiths M. 2010. Improving the Safety and Quality of Milk:Improving Quality in Milk Products. Woodhead PublishingLimited, Cambridge.Guan Y G, Wu X L, Meng H C. 2013. Indirect competitiveELISA based on monoclonal antibody for the detection of5-hydroxymethyl-2-furfural in milk, compared with HPLC.Journal of Dairy Science, 96, 4885-4890Guirgis B S, E Cunha C S, Gomes I, Cavadas M, Silva I, DoriaG, Blatch G L, Baptista P V, Pereira E, Azzazy H M. 2012.Gold nanoparticle-based fluorescence immunoassay formalaria antigen detection. Analytical and BioanalyticalChemistry, 402, 1019-1027Guo H, Sun S. 2012. Lanthanide-doped upconverting phosphorsfor bioassay and therapy. Nanoscale, 4, 6692-6706Guo J N, Liu L Q, Xue F, Xing C R, Song S S, Kuang H, XuC L. 2015. Development of a monoclonal antibody-basedimmunochromatographic strip for cephalexin. Food andAgricultural Immunology, 26, 282-292De Guzmán-Vázquez Prada A, Reviejo A J, Pingarrón J M.2006. A method for the quantification of low concentrationsulfamethazine residues in milk based on molecularly imprinted clean-up and surface preconcentration at aNafion-modified glassy carbon electrode. Journal ofPharmaceutical and Biomedical Analysis, 40, 281-286Hayat M A. 2012. Colloidal Gold: Principles, Methods, andApplications. Elsevier, U.S.Hernandes T, Dores E, Ribeiro M L, Rossignoli P A, Malm O.2014. Simple method to determine residual cypermethrinand deltamethrin in bovine milk. Journal of the BrazilianChemical Society, 25, 1656-1661Huang Y, Liu D, Lai W, Xiong Y, Yang W, Liu K, Wang S. 2014.Rapid detection of aflatoxin M1 by immunochromatographycombined with enrichment based on immunomagneticnanobead. Chinese Journal of Analytical Chemistry, 42,654-659IDEXX. 2015. IDEXX dairy tests and accessories. [2015-03-13].https://www.idexx.com/dairy/accessories.htmInternational Dairy Federation. 2014. The World Dairy Situation2014. Bulletin of the World Dairy Federation.Jiang W X, Beloglazova N V, Wang Z H, Jiang H Y, Wen K, deSaeger S, Luo P J, Wu Y N, Shen J Z. 2015. Developmentof a multiplex flow-through immunoaffinity chromatographytest for the on-site screening of 14 sulfonamide and 13quinolone residues in milk. Biosensors & Bioelectronics,66, 124-128Jiang W X, Wang Z H, Nolke G, Zhang J, Niu L L, Shen J Z. 2013.Simultaneous determination of aflatoxin B-1 and aflatoxinM-1 in food matrices by enzyme-linked immunosorbentassay. Food Analytical Methods, 6, 767-774Jin Y, Jang J W, Lee M H, Han C H. 2006. Development ofELISA and immunochromatographic assay for the detectionof neomycin. Clinica Chimica Acta, 364, 260-266Karami-Osboo R, Shojaee M H, Miri R, Kobarfard F, Javidnia K.2014. Simultaneous determination of six fluoroquinolonesin milk by validated QuEChERS-DLLME HPLC-FLD.Analytical Methods, 6, 5632-5638Kloth K, Rye-Johnsen M, Didier A, Dietrich R, Märtlbauer E,Niessner R, Seidel M. 2009. A regenerable immunochipfor the rapid determination of 13 different antibiotics in rawmilk. Analyst, 134, 1433-1439Köhler G, Milstein C. 1975. Continuous cultures of fused cellssecreting antibody of predefined specificity. Nature, 256,495-497Korpimäki T, Brockmann E, Kuronen O, Saraste M, LamminmäkiU, Tuomola M. 2004. Engineering of a broad specificityantibody for simultaneous detection of 13 sulfonamidesat the maximum residue level. Journal of Agricultural andFood Chemistry, 52, 40-47Lan H, Gan N, Pan D, Hu F, Li T, Long N, Qiao L. 2014. Anautomated solid-phase microextraction method based onmagnetic molecularly imprinted polymer as fiber coatingfor detection of trace estrogens in milk powder. Journal ofChromatographya, 1331, 10-18Leivo J, Lamminmäki U, Lövgren T, Vehniäinen M. 2013.Multiresidue detection of fluoroquinolones: Specificityengineering of a recombinant antibody with oligonucleotidedirectedmutagenesis. Journal of Agricultural and FoodChemistry, 61, 11981-11985Li Y S, Zhang Y R, Cao X Y, Wang Z H, Shen J Z, Zhang SX. 2012. Development of a chemiluminescent competitiveindirect ELISA method procedure for the determinationof gentamicin in milk. Analytical Methods, 4, 2151-2155Liang X, Ni H J, Beier R C, Dong Y N, Li J Y, Luo X S, ZhangS X, Shen J Z, Wang Z H. 2014. Highly broad-specificand sensitive enzyme-linked immunosorbent assay forscreening sulfonamides: Assay optimization and applicationto milk samples. Food Analytical Methods, 7, 1992-2002Liang X, Wang Z, Wang C, Wen K, Mi T, Zhang J, ZhangS. 2013. A proof-of-concept receptor-based assay forsulfonamides. Analytical Biochemistry, 438, 110-116de Lima G C, Lago A C D, Chaves A A, Fadini P S, Luccas P O.2013. Determination of selenium using atomically imprintedpolymer (AIP) and hydride generation atomic absorptionspectrometry. Analytica Chimica Acta, 768, 35-40Liotta L A, Christiansen B C, Day A R, Harlacher T, PaweletzK. 1999. Light-Emitting Immunoassay. Google Patents.US5942407.Liu D, Huang Y, Wang S, Liu K, Chen M, Xiong Y, Yang W,Lai W. 2015. A modified lateral flow immunoassay for thedetection of trace aflatoxin M1 based on immunomagneticnanobeads with different antibody concentrations. FoodControl, 51, 218-224Liu L Q, Luo L J, Suryoprabowo S, Peng J, Kuang H, Xu C L.2014. Development of an immunochromatographic striptest for rapid detection of ciprofloxacin in milk samples.Sensors, 14, 16785-16798Liu N, Song S Q, Lu L, Nie D X, Han Z, Yang X L, Zhao Z H, WuA B, Zheng X D. 2014. A rabbit monoclonal antibody-basedsensitive competitive indirect enzyme-linked immunoassayfor rapid detection of chloramphenicol residue. Food andAgricultural Immunology, 25, 523-534Liu T S, Xie J, Zhao J F, Song G X, Hu Y M. 2014. Magneticchitosan nanocomposite used as cleanup material todetect chloramphenicol in milk by GC-MS. Food AnalyticalMethods, 7, 814-819Luo Y, Xia Y. 2012. Selection of single-chain variable fragmentantibodies against fenitrothion by ribosome display.Analytical Biochemistry, 421, 130-137Lv Y, Wang L, Yang L, Zhao C, Sun H. 2012. Synthesis andapplication of molecularly imprinted poly(methacrylic acid)-silica hybrid composite material for selective solid-phaseextraction and high-performance liquid chromatographydetermination of oxytetracycline residues in milk. Journalof Chromatographya, 1227, 48-53Mansfield M A. 2009. Nitrocellulose membranes for lateralflow immunoassays: A technical treatise. In: Lateral FlowImmunoassayp. Humana Press, Springer, U.S. pp. 1-19Medibena. 2014. MaxSignal® Aflatoxin B1 ELISA test kit. [2015-03-15]. http://www.biooscientific.com/Mycotoxin-test-kits/MaxSignal-Aflatoxin-B1-ELISA-Test-KitMeneghini L Z, Rubensam G, Bica V C, Ceccon A, Barreto F, Ferrao M F, Bergold A M. 2014. Multivariate optimizationfor extraction of pyrethroids in milk and validation for GCECDand CG-MS/MS analysis. International Journal ofEnvironmental Research and Public Health, 11, 11421-11437Mi T J, Liang X, Ding L, Zhang S X, Eremin S A, Beier R C,Shen J Z, Wang Z H. 2014. Development and optimizationof a fluorescence polarization immunoassay for orbifloxacinin milk. Analytical Methods, 6, 3849-3857MOA (Ministry of Agriculture of the People’s Republic China).2002. Annoucement of No. 235. Maximum residue limit ofveterinary drugs in animal origin food. [2015-03-15]. http://www.moa.gov.cn/zwllm/tzgg/gg/200302/t20030226_59300.htm (in Chinese)Moghaddam A, Løbersli I, Gebhardt K, Braunagel M, Marvik O J.2001. Selection and characterisation of recombinant singlechainantibodies to the hapten Aflatoxin-B1 from naiverecombinant antibody libraries. Journal of ImmunologicalMethods, 254, 169-181Mohamed R, Richoz-Payot J, Gremaud E, Mottier P, Yilmaz E,Tabet J, Guy P A. 2007. Advantages of molecularly imprintedpolymers LC-ESI-MS/MS for the selective extraction andquantification of chloramphenicol in milk-based matrixes.Comparison with a classical sample preparation. AnalyticalChemistry, 79, 9557-9565Ni H, Zhang S, Ding X, Mi T, Wang Z, Liu M. 2014. Determinationof enrofloxacin in bovine milk by a novel single-strandedDNA aptamer chemiluminescent enzyme immunoassay.Analytical Letters, 47, 2844-2856Pilehvar S, Dierckx T, Blust R, Breugelmans T, De Wael K. 2014.An electrochemical impedimetric aptasensing platform forsensitive and selective detection of small molecules suchas chloramphenicol. Sensors, 14, 12059-12069Porter J, O´ Loan N, Bell B, Mahoney J, Mcgarrity M, McconnellR I, Fitzgerald S P. 2012. Development of an Evidencebiochip array kit for the multiplex screening of more than 20anthelmintic drugs. Analytical and Bioanalytical Chemistry,403, 3051-3056Qi Y, Wu C, Zhang S, Wang Z, Huang S, Dai L, Wang S, Xia L,Wen K, Cao X. 2009. Selection of anti-sulfadimidine specificScFvs from a hybridoma cell by eukaryotic ribosome display.PLoS ONE, 4, e6427.Raz R S, Bremer M G, Haasnoot W, Norde W. 2009. Label-freeand multiplex detection of antibiotic residues in milk usingimaging surface plasmon resonance-based immunosensor.Analytical Chemistry, 81, 7743-7749Rusanova T Y, Beloglazova N V, Goryacheva I Y, Lobeau M,Van Peteghem C, De Saeger S. 2009. Non-instrumentalimmunochemical tests for rapid ochratoxin A detection inred wine. Analytica Chimica Acta, 653, 97-102Sadeghi N, Oveisi M R, Jannat B, Hajimahmoodi M, BehfarA, Behzad M, Norouzi N, Oveisi M, Jannat B. 2014.Simultaneous measurement of zinc, copper, lead andcadmium in baby weaning food and powder milk by DPASV.Iranian Journal of Pharmaceutical Research, 13, 345-349Sefah K, Shangguan D, Xiong X, O’Donoghue M B, Tan W.2010. Development of DNA aptamers using Cell-SELEX,5, 1169-1185Seidel M, Niessner R. 2014. Chemiluminescence microarraysin analytical chemistry: A critical review. Analytical andBioanalytical Chemistry, 406, 5589-5612Shen J, Xu F, Jiang H, Wang Z, Tong J, Guo P, Ding S. 2007.Characterization and application of quantum dot nanocrystalmonoclonalantibody conjugates for the determination ofsulfamethazine in milk by fluoroimmunoassay. Analyticaland Bioanalytical Chemistry, 389, 2243-2250Sheng W, Li Y Z, Xu X, Yuan M, Wang S. 2011. Enzymelinkedimmunosorbent assay and colloidal gold-basedimmunochromatographic assay for several (fluoro)quinolones in milk. Microchimica Acta, 173, 307-316Sniegocki T, Posyniak A, Gbylik-Sikorska M, Zmudzki J.2014. Determination of chloramphenicol in milk using aQuEChERS-based on liquid chromatography tandem massspectrometry method. Analytical Letters, 47, 568-578Song X, Xu S, Chen L, Wei Y, Xiong H. 2014. Recent advancesin molecularly imprinted polymers in food analysis. Journalof Applied Polymer Science, 131, 1-18Speranskaya E S, Beloglazova N V, Lenain P, De Saeger S,Wang Z, Zhang S, Hens Z, Knopp D, Niessner R, PotapkinD V, Goryacheva I Y. 2014. Polymer-coated fluorescentCdSe-based quantum dots for application in immunoassay.Biosensors and Bioelectronics, 53, 225-231Sui J, Lin H, Cao L, Li Z. 2009. Dot-immunogold filtration assayfor rapid screening of three fluoroquinolones. Food andAgricultural Immunology, 20, 125-137Suryoprabowo S, Liu L Q, Peng J, Kuang H, Xu C L. 2014.Development of a broad specific monoclonal antibodyfor fluoroquinolone analysis. Food Analytical Methods, 7,2163-2168Tao X Q, Jiang H Y, Yu X Z, Zhu J H, Wang X, Wang ZH, Niu L L, Wu X P, Shen J Z. 2013. An ultrasensitivechemiluminescence immunoassay of chloramphenicolbased on gold nanoparticles and magnetic beads. DrugTesting and Analysis, 5, 346-352Taranova N A, Berlina A N, Zherdev A V, Dzantiev B B. 2015.‘Traffic light’ immunochromatographic test based onmulticolor quantum dots for the simultaneous detection ofseveral antibiotics in milk. Biosensors and Bioelectronics,63, 255-261Tien Y J, Chan C, Chan K, Wang Y C, Lin J, Chang C, ChenC. 2013. Development of a novel bead-based 96-wellfiltration plate competitive immunoassay for the detection ofgentamycin. Biosensors and Bioelectronics, 49, 126-132Tillib S V. 2011. “Camel nanoantibody” is an efficient tool forresearch, diagnostics and therapy. Molecular Biology, 45,66-73 (in Russia)Tillib S V, Ivanova T I, Vasilev L A. 2010. Fingerprint-likeanalysis of “Nanoantibody” selection by phage displayusing two helper phage variants. Acta Naturae, 2, 85-93Toh S Y, Citartan M, Gopinath S C, Tang T. 2015. Aptamers as a replacement for antibodies in enzyme-linkedimmunosorbent assay. Biosensors and Bioelectronics, 64,392-403Wang C, Wang Z, Jiang W, Mi T, Shen J. 2012. A monoclonalantibody-based ELISA for multiresidue determination ofavermectins in milk. Molecules, 17, 7401-7414Wang J, Liu B, Hsu Y, Yu F. 2011. Sensitive competitive directenzyme-linked immunosorbent assay and gold nanoparticleimmunochromatographic strip for detecting aflatoxin M1 inmilk. Food Control, 22, 964-969Wang Q, Haughey S A, Sun Y, Eremin S A, Li Z, Liu H, XuZ, Shen Y, Lei H. 2011. Development of a fluorescencepolarization immunoassay for the detection of melaminein milk and milk powder. Analytical and BioanalyticalChemistry, 399, 2275-2284Wang Q, Nchimi Nono K, Syrjänpää M, Charbonnie?re L J,Hovinen J, Härmä H. 2013. Stable and highly fluorescenteuropium (iii) chelates for time-resolved immunoassays.Inorganic Chemistry, 52, 8461-8466Wang Y, Wang D, Zou M, Jin Y, Yun C, Gao X. 2011. Applicationof suspension array for simultaneous detection of antibioticresidues in raw milk. Analytical Letters, 44, 2711-2720Wang Y Z, Yang H, Pschenitza M, Niessner R, Li Y, Knopp D,Deng A P. 2012. Highly sensitive and specific determinationof mercury (II) ion in water, food and cosmetic samples withan ELISA based on a novel monoclonal antibody. Analyticaland Bioanalytical Chemistry, 403, 2519-2528Wang Z H, Sheng Y J, Duan H X, Yu Q, Shi W M, Zhang SX. 2014. New haptens synthesis, antibody production andcomparative molecular field analysis for tetracyclines. RSCAdvances, 4, 53788-53794Watanabe H, Satake A, Kido Y, Tsuji A. 2002. Monoclonalbasedenzyme-linked immunosorbent assay andimmunochromatographic rapid assay for dihydrostreptomycinin milk. Analytica Chimica Acta, 472, 45-53Wild D. 2013. The Immunoassay Handbook: Theory andApplications of Ligand Binding, ELISA and RelatedTechniques. Sockton Press, New York.Wu J, Xu F, Zhu K, Wang Z H, Wang Y H, Zhao K X, LiX W, Jiang H Y, Ding S Y. 2013. Rapid and sensitivefluoroimmunoassay based on quantum dots for detectionof melamine in milk. Analytical Letters, 46, 275-285Wu J X, Zhang S E, Zhou X P. 2010. Monoclonal antibody-basedELISA and colloidal gold-based immunochromatographicassay for streptomycin residue detection in milk and swineurine. Journal of Zhejiang University (Science B), 11, 52-60Xie Q, Wu Y, Xiong Q, Xu H, Xiong Y, Liu K, Jin Y, Lai W. 2014.Advantages of fluorescent microspheres compared withcolloidal gold as a label in immunochromatographic lateralflow assays. Biosensors and Bioelectronics, 54, 262-265Xu F, Jiang W X, Zhou J, Wen K, Wang Z H, Jiang H Y, Ding S Y.2014. Production of monoclonal antibody and developmentof a new immunoassay for apramycin in food. Journal ofAgricultural and Food Chemistry, 62, 3108-3113Xu X, Draney D R, Cheung L. 2013. Cyanine Dyes and TheirConjugates. Google Patents. WO2012054749A1.Yang W, Li X, Liu G, Zhang B, Zhang Y, Kong T, Tang J,Li D, Wang Z. 2011. A colloidal gold probe-based silverenhancement immunochromatographic assay for the rapiddetection of abrin-a. Biosensors and Bioelectronics, 26,3710-3713Ye B, Li S, Zuo L, Li X. 2008. Simultaneous detection ofsulfamethazine, streptomycin, and tylosin in milk bymicroplate-array based SMM-FIA. Food Chemistry, 106,797-803Young M S, Tran K V, Goh E, Shia J C. 2014. A rapid spebasedanalytical method for UPLC/MS/MS determination ofaminoglycoside antibiotic residues in bovine milk, muscle,and kidney. Journal of AOAC International, 97, 1737-1741Yuan M, Sheng W, Zhang Y, Wang J, Yang Y, ZhangS, Goryacheva I Y, Wang S. 2012. A gel-basedvisual immunoassay for non-instrumental detection ofchloramphenicol in food samples. Analytica Chimica Acta,751, 128-134Zeng K, Zhang J, Wang Y, Wang Z H, Zhang S X, Wu C M,Shen J Z. 2013. Development of a rapid multi-residue assayfor detecting β-lactams using penicillin binding protein 2x*.Biomedical and Environmental Sciences, 26, 100-109Zhang D H, Li P W, Zhang Q, Yang Y, Zhang W, Guan D, DingX X. 2012. Extract-free immunochromatographic assay foron-site tests of aflatoxin M-1 in milk. Analytical Methods,4, 3307-3313Zhang G P, Wang F Y, Song C M, Zhi A M, Hu X F, Zhao D.2013. Preparation of Fluorescence Strip Based on Silicafor Quantity Analysis of Gentamicin. CN103439489A. (inChinese)Zhang J, Wang Z H, Mi T J, Wenren L Q, Wen K. 2014. Ahomogeneous fluorescence polarization immunoassay forthe determination of cephalexin and cefadroxil in milk. FoodAnalytical Methods, 7, 879-886Zhang J, Zhang B, Wu Y, Jia S, Fan T, Zhang Z, Zhang C. 2010.Fast determination of the tetracyclines in milk samples bythe aptamer biosensor. Analyst, 135, 2706-2710Zhang J K, Qi Y H, Liu J X, Wang J P. 2013. Heterologousimmunoassay for screening macrolide antibiotics residuesin milk based on the monoclonal antibody of tylosin. Foodand Agricultural Immunology, 24, 419-431Zhao L, Sun L, Chu X. 2009. Chemiluminescence immunoassay.Trends in Analytical Chemistry, 28, 404-415Zheng G C, Han C, Liu Y, Wang J, Zhu M W, Wang C J, Shen Y.2014. Multiresidue analysis of 30 organochlorine pesticidesin milk and milk powder by gel permeation chromatographysolidphase extraction-gas chromatography-tandem massspectrometry. Journal of Dairy Science, 97, 6016-6026Zheng M, Gong R, Zhao X, Feng Y. 2010. Selective samplepretreatment by molecularly imprinted polymer monolith forthe analysis of fluoroquinolones from milk samples. Journalof Chromatographya, 1217, 2075-2081Zhou J, Zhu K, Xu F, Wang W J, Jiang H Y, Wang Z H, Ding SY. 2014. Development of a microsphere-based fluorescenceimmunochromatographic assay for monitoring lincomycin inmilk, honey, beef, and swine urine. Journal of Agricultural and Food Chemistry, 62, 12061-12066Zhou Y, Tian X L, Li Y S, Pan F G, Zhang Y Y, Zhang J H,Wang X R, Ren H L, Lu S Y, Li Z H, Liu Z S, Chen Q J,Liu J Q. 2012. Development of a monoclonal antibodybasedsandwich-type enzyme-linked immunosorbentassay (ELISA) for detection of abrin in food samples. FoodChemistry, 135, 2661-2665Zhu K, Li J, Wang Z, Jiang H, Beier R C, Xu F, Shen J, DingS. 2011. Simultaneous detection of multiple chemicalresidues in milk using broad-specificity antibodies in a hybridimmunosorbent assay. Biosensors and Bioelectronics, 26,2716-2719Zhu L, Cui X, Wu J, Wang Z, Wang P, Hou Y. 2014.Fluorescence immunoassay based on carbon dots as labelsfor the detection of human immunoglobulin G. AnalyticalMethods, 6, 4430-4436 |
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