Messages from Powdery Mildew DNA: How the Interplay with a Host Moulds Pathogen Genomes

doi:10.1016/S2095-3119(13)60650-4

Journal of Integrative Agriculture ›› 2014, Vol. 13 ›› Issue (2): 233-236.DOI: 10.1016/S2095-3119(13)60650-4

Messages from Powdery Mildew DNA: How the Interplay with a Host Moulds Pathogen Genomes

Pietro D Spanu

Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom

收稿日期:2013-07-09 出版日期:2014-02-01 发布日期:2014-02-06
通讯作者: Pietro D Spanu, Tel: +44-207-5945384, Fax: +44-207-5842056, E-mail: p.spanu@imperial.ac.uk
作者简介:Pietro D Spanu, Tel: +44-207-5945384, Fax: +44-207-5842056
基金资助:
In summary, it appears that the structure of the ge-nome (size inflation, abundance of the repetitive DNA originating from retro-transposition) and gene loss (eventually leading to obligate biotrophy) were prices paid by the mildews to increase variation useful in their continuing struggle in an evolutionary battlefield represented by ever changing host immunity.

Messages from Powdery Mildew DNA: How the Interplay with a Host Moulds Pathogen Genomes

Pietro D Spanu

Department of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom

Received:2013-07-09 Online:2014-02-01 Published:2014-02-06
Contact: Pietro D Spanu, Tel: +44-207-5945384, Fax: +44-207-5842056, E-mail: p.spanu@imperial.ac.uk
About author:Pietro D Spanu, Tel: +44-207-5945384, Fax: +44-207-5842056
Supported by:
In summary, it appears that the structure of the ge-nome (size inflation, abundance of the repetitive DNA originating from retro-transposition) and gene loss (eventually leading to obligate biotrophy) were prices paid by the mildews to increase variation useful in their continuing struggle in an evolutionary battlefield represented by ever changing host immunity.

摘要/Abstract

摘要： The genomes of the barley, Arabidopsis and pea powdery mildew are significantly larger than those of related fungi. This is due to an extraordinary expansion of retro-trasposons that are evident as repetitive elements in the sequence. The protein coding genes are fewer than expected due to an overall reduction in the size of gene families, a reduction in the number of paralogs and because of the loss of certain metabolic pathways. Many of these changes have also been observed in the genomes of other taxonomically unrelated obligate biotrophic pathogens. The only group of genes that bucks the trend of gene loss, are those encoding small secreted proteins that bear the hall marks of effectors.

关键词: barley powdery mildew , genome , effectors

Abstract: The genomes of the barley, Arabidopsis and pea powdery mildew are significantly larger than those of related fungi. This is due to an extraordinary expansion of retro-trasposons that are evident as repetitive elements in the sequence. The protein coding genes are fewer than expected due to an overall reduction in the size of gene families, a reduction in the number of paralogs and because of the loss of certain metabolic pathways. Many of these changes have also been observed in the genomes of other taxonomically unrelated obligate biotrophic pathogens. The only group of genes that bucks the trend of gene loss, are those encoding small secreted proteins that bear the hall marks of effectors

Key words: barley powdery mildew , genome , effectors

Pietro D Spanu. Messages from Powdery Mildew DNA: How the Interplay with a Host Moulds Pathogen Genomes[J]. Journal of Integrative Agriculture, 2014, 13(2): 233-236.

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Messages from Powdery Mildew DNA: How the Interplay with a Host Moulds Pathogen Genomes

Messages from Powdery Mildew DNA: How the Interplay with a Host Moulds Pathogen Genomes

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