The Effects of Different Sex-Linked Dwarf Variations on Chinese Native Chickens

doi:10.1016/S1671-2927(00)8682

Journal of Integrative Agriculture ›› 2012, Vol. 12 ›› Issue (9): 1500-1508.DOI: 10.1016/S1671-2927(00)8682

The Effects of Different Sex-Linked Dwarf Variations on Chinese Native Chickens

OUYANG Jian-hua, XIE Liang, NIE Qing-hua, ZENG Hua, PENG Zhi-jun, ZHANG De-xiang, ZHANG Xi-quan

1.Department of Animal Science, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, P.R.China
2.Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, P.R.China
3.Guangdong Wens Foodstuff Company Ltd., Guangdong 527439, P.R.China
4.Institute of Animal Science & Veterinary, Hainan Academy of Agricultural Sciences, Haikou 571100, P.R.China

收稿日期:2011-04-22 出版日期:2012-09-01 发布日期:2012-09-09
通讯作者: Correspondence ZHANG Xi-quan, Tel: +86-20-85285703, Fax: +86-20-85280740, E-mail: xqzhang@scau.edu.cn
基金资助:
The current work was funded by projects under the Major State Basic Research Development Program China (2006CB102107) and the earmarked fund for Modern Agro- Industry Technology Research System (nycytx-42-G1-04). It was also supported by the National High Technology Research and Development Program of China (863 Program, 2010AA10A102).

The Effects of Different Sex-Linked Dwarf Variations on Chinese Native Chickens

OUYANG Jian-hua, XIE Liang, NIE Qing-hua, ZENG Hua, PENG Zhi-jun, ZHANG De-xiang, ZHANG Xi-quan

1.Department of Animal Science, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, P.R.China
2.Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, P.R.China
3.Guangdong Wens Foodstuff Company Ltd., Guangdong 527439, P.R.China
4.Institute of Animal Science & Veterinary, Hainan Academy of Agricultural Sciences, Haikou 571100, P.R.China

Received:2011-04-22 Online:2012-09-01 Published:2012-09-09
Contact: Correspondence ZHANG Xi-quan, Tel: +86-20-85285703, Fax: +86-20-85280740, E-mail: xqzhang@scau.edu.cn
Supported by:
The current work was funded by projects under the Major State Basic Research Development Program China (2006CB102107) and the earmarked fund for Modern Agro- Industry Technology Research System (nycytx-42-G1-04). It was also supported by the National High Technology Research and Development Program of China (863 Program, 2010AA10A102).

摘要/Abstract

摘要： Variants in chicken growth hormone receptor (GHR) gene lead to sex-linked dwarf (SLD) chickens, but effects of different variants are distinct. In this study, 11 SLD chicken breeds or strains including 3 Chinese native breeds and 8 breeding strains were studied in order to investigate the effects of different sex-linked dwarf variations on growth performance. The results showed that there were three reasons which could lead to dwarfism in the 11 breeds or strains. Firstly, an about 1.7 kb deletion of growth hormone receptor (GHR) gene leads to dwarfism in Jiangxi dwarf chicken, strains GF24, GF26, N308, N309, and N310. Secondly, a T354C mutation in exon 5 of the GHR gene leads to dwarfism in strains N301 and N305. Thirdly, an unknown variant leads to dwarfism in Guizhou Yellow Dwarf chicken and Yixing Bantam chicken. In addition, all individuals of N303 had the 1.7 kb deletion of the GHR gene, and additionally, some of them also carried the T354C mutation. As far as the performance of individuals were compared among T354C homozygote, deletion homozygote, and heterozygote carrying both T354C and deletion, it was found that the T354C’s impacts on body weight of Chinese chickens were maximum, the body weight of chickens with homozygote T354C was 92.12% of those with heterozygote, and the difference of the body weight between deletion homozygote and heterozygote was not significant. There was no significant difference of shank length among three genotypes.

关键词: SLD chicken, GHR, dwarf allele, phenotypic effect

Abstract: Variants in chicken growth hormone receptor (GHR) gene lead to sex-linked dwarf (SLD) chickens, but effects of different variants are distinct. In this study, 11 SLD chicken breeds or strains including 3 Chinese native breeds and 8 breeding strains were studied in order to investigate the effects of different sex-linked dwarf variations on growth performance. The results showed that there were three reasons which could lead to dwarfism in the 11 breeds or strains. Firstly, an about 1.7 kb deletion of growth hormone receptor (GHR) gene leads to dwarfism in Jiangxi dwarf chicken, strains GF24, GF26, N308, N309, and N310. Secondly, a T354C mutation in exon 5 of the GHR gene leads to dwarfism in strains N301 and N305. Thirdly, an unknown variant leads to dwarfism in Guizhou Yellow Dwarf chicken and Yixing Bantam chicken. In addition, all individuals of N303 had the 1.7 kb deletion of the GHR gene, and additionally, some of them also carried the T354C mutation. As far as the performance of individuals were compared among T354C homozygote, deletion homozygote, and heterozygote carrying both T354C and deletion, it was found that the T354C’s impacts on body weight of Chinese chickens were maximum, the body weight of chickens with homozygote T354C was 92.12% of those with heterozygote, and the difference of the body weight between deletion homozygote and heterozygote was not significant. There was no significant difference of shank length among three genotypes.

Key words: SLD chicken, GHR, dwarf allele, phenotypic effect

OUYANG Jian-hua, XIE Liang, NIE Qing-hua, ZENG Hua, PENG Zhi-jun, ZHANG De-xiang, ZHANG Xi-quan. The Effects of Different Sex-Linked Dwarf Variations on Chinese Native Chickens[J]. Journal of Integrative Agriculture, 2012, 12(9): 1500-1508.

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The Effects of Different Sex-Linked Dwarf Variations on Chinese Native Chickens

The Effects of Different Sex-Linked Dwarf Variations on Chinese Native Chickens

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