微小RNA介导意大利蜜蜂工蜂对东方蜜蜂微孢子虫的跨界调控

杜宇,范小雪,蒋海宾,王杰,冯睿蓉,张文德,余岢骏,隆琦,蔡宗兵,熊翠玲,郑燕珍,陈大福,付中民,徐国钧,郭睿

MicroRNA-Mediated Cross-Kingdom Regulation of Apis mellifera ligustica Worker to Nosema ceranae

DU Yu,FAN XiaoXue,JIANG HaiBin,WANG Jie,FENG RuiRong,ZHANG WenDe,YU KeJun,LONG Qi,CAI ZongBing,XIONG CuiLing,ZHENG YanZhen,CHEN DaFu,FU ZhongMin,XU GuoJun,GUO Rui

图4 AmCK1 vs AmT1比较组中显著性DEmiRNA及其靶向的NcCK vs NcT1比较组中毒力因子/侵染因子相关DEmRNA的调控网络 A：宿主的显著性DEmiRNA与病原的ABC转运蛋白、ATP/ADP转位酶相关DEmRNA的调控网络Regulatory network of host significant DEmiRNAs and pathogen DEmRNAs associated with ABC transporter and ATP/ADP translocase;B：宿主的显著性DEmiRNA与病原的蓖麻毒素B凝集素、孢壁蛋白和极管蛋白相关DEmRNA的调控网络Regulatory network of host significant DEmiRNAs and pathogen DEmRNAs associated with ricin B lectin, spore wall protein and polar tube protein;C：宿主的显著性DEmiRNA与病原的糖酵解/糖异生途径相关DEmRNA的调控网络Regulatory network of host significant DEmiRNAs and pathogen DEmRNAs associated with glycolysis/gluconeogenesis pathway

Fig. 4 Regulatory networks of significant DEmiRNAs in AmCK1 vs AmT1 and their target DEmRNAs associated with virulence factor/infection factor in NcCK vs NcT1