猪基因组选择“两步走”策略的计算机模拟评估

唐振双,殷东,尹立林,马云龙,项韬,朱猛进,余梅,刘小磊,李新云,邱小田,赵书红

To Evaluate the “Two-Step” Genomic Selection Strategy in Pig by Simulation

TANG ZhenShuang,YIN Dong,YIN LiLin,MA YunLong,XIANG Tao,ZHU MengJin,YU Mei,LIU XiaoLei,LI XinYun,QIU XiaoTian,ZHAO ShuHong

表1 模拟参数

Table 1 The parameters of simulation

类型 Type 参数Parameter 遗传力Heritability 性状1为0.3,性状2为0.1 Trait 1 is 0.3, trait 2 is 0.1 QTN的数目及效应 The number of QTN and effect 100个QTNs,正态分布 100 QTNS, normal distribution 留种率Fraction selected 杜洛克：母猪15%、公猪1% Duroc: dam 15%, sire 1% 长白：母猪10%、公猪1% Landrace: dam 10%, sire 1% 大白：母猪10%、公猪1% Yorkshire: dam 10%, sire 1% 每窝公母猪比例 Ratio of sires and dams per litter 1:1 产仔数Litter size 杜洛克：8头;长白：13头;大白：14头 Duroc: 8; Landrace: 13; Yorkshire: 14 群体更新率Population renewal rate 母猪为60%,公猪为100% Dam: 60%, Sire: 100% 群体结构Population structure N1 N2 N3 N4（待选）To be selected 杜洛克母猪：1000头;长白母猪：500头;大白母猪：2000头;各品种公猪：30头 The dam number of Duroc, Landrace, Yorkshire is 1000, 500, 2000; The sire number of all breeds is 30 杜洛克母猪：1000头;长白母猪：500头;大白母猪：2000头;各品种公猪：30头 The dam number of Duroc, Landrace, Yorkshire is 1000, 500, 2000; The sire number of all breeds is 30 杜洛克母猪：1000头;长白母猪：500头;大白母猪：2000头;各品种公猪：30头 The dam number of Duroc, Landrace, Yorkshire is 1000, 500, 2000; The sire number of all breeds is 30 杜洛克：8000头;长白：6500头;大白：28000头 The number of Duroc, Landrace, Yorkshire is 8000, 6500, 28000 表型个体 Phenotype N1—N3 每个世代抽取50%的个体,N4世代 The 50% individuals in 1-3 generation and all individuals in 4 generation 基因型个体 Genotype N1—N3世代共抽取1000头或3000头,N4世代抽取10%或30%的个体 Total 1000 or 3000 individuals 1-3 generation and 10% or 30% individuals in 4 generation