外泌体microRNA在猪成熟和闭锁卵泡中的表达差异及功能分析

陈慧芳,黄绮亮,胡智超,潘晓婷,吴志胜,白银山

Expression Differences and Functional Analysis of Exosomes microRNA in Porcine Mature and Atretic Follicles

CHEN HuiFang,HUANG QiLiang,HU ZhiChao,PAN XiaoTing,WU ZhiSheng,BAI YinShan

表1 卵泡液EXs中主要差异表达的miRNA

Table 1 The main differential expression miRNA in follicular fluid EXs

miRNA名称 miRNA name mffEXs-TPM mffEXs-Tags per million affEXs-TPM affEXs-Tags per million 差异倍数 Fold change ssc-miR-1 191.1357 3683.4041 4.268370509 ssc-miR-133a-3p 125.3327 1137.3101 3.181790898 ssc-miR-874 588.8902 4261.314 2.855227792 ssc-let-7a 359.4472 2278.7335 2.664380439 ssc-let-7f-5p 378.9345 1986.6937 2.39034906 ssc-miR-23b 121.4619 631.3819 2.378009061 ssc-miR-486 810.8585 4166.7095 2.361386438 ssc-miR-6529 548.7143 2743.5294 2.321905957 ssc-miR-26a 2160.5543 9279.4636 2.102639923 ssc-miR-99b 13585.3175 38933.8489 1.51897669 ssc-miR-202-3p 2947.6543 7512.8282 1.349788776 ssc-miR-1271-5p 22519.3101 52612.4199 1.224240778 ssc-miR-21-5p 555532.4026 444467.5 - 0.321793131 ssc-miR-143 1443.9288 621.0989 -1.2171 ssc-miR-10b 163814.113 68106.9853 -1.266184975 ssc-miR-140-3p 5264.5074 2046.3356 -1.363255777 ssc-miR-10a-5p 7077.7606 2453.5461 -1.528424586 ssc-miR-2320-5p 146.8221 49.3588 -1.572689917 ssc-miR-125b 13217.7283 3973.3874 -1.734032879 ssc-miR-16 371.46 109.0008 -1.768868142 ssc-miR-146a-5p 6504.7539 1748.1259 -1.895685384 ssc-miR-145-3p 975.5663 257.0773 -1.924037697 ssc-miR-744 367.4557 94.6045 -1.957589617 ssc-miR-184 584.4855 121.3405 -2.268106073 ssc-miR-30d 3433.5021 707.4768 -2.278926102 ssc-miR-132 301.9197 47.3022 -2.674185705 ssc-miR-125a 18571.3967 1441.6897 -3.687249733