禽源奇异变形杆菌质粒介导AmpC酶基因型检测与质粒分析

赵世玉,焦嘉杰,董宁宁,潘圆月,崔孟梅,潘玉善

Analysis of Plasmid-Mediated AmpC β-lactamases Gene and Plasmid in Poultry Proteus mirabilis Strains

ZHAO ShiYu,JIAO JiaJie,DONG NingNing,PAN YuanYue,CUI MengMei,PAN YuShan

图2 质粒pC12与其他blaCMY阳性IncC质粒的序列比较 奇异变形杆菌质粒pC12 （MT320534）,大肠杆菌质粒pAR060302 （FJ621588）和pUMNK88 （HQ023862）,沙门氏菌质粒pSN254 （CP000604）,pCVM22425 （CP009560）和pSD_174 （JF267651）,肺炎克雷伯氏菌质粒IncA/C-LS6（JX442976） 红色箭头代表药物或汞抗性基因;黄色箭头代表插入序列或转座酶基因;蓝绿色代表与接合转移相关的基因;橙色箭头代表与质粒维持和稳定相关的基因;灰色箭头代表编码假设蛋白的基因。灰色背景代表≥94%的相似度序列

Fig. 2 Sequence comparisons of pC12 and other blaCMY-positive IncC plasmids pAR060302 (FJ621588), pSN254 (CP000604), pCVM22425 (CP009560), pSD_174 (JF267651), pUMNK88 (HQ023862), IncA/C-LS6 (JX442976) from P. mirabilis, E. coli, S. enterica, and K. pneumoniae Red arrows represent genes coding for antibiotic resistance or mercury resistance; yellow arrows represent genes coding for insertion sequence elements or transposase; cyan arrows represent genes coding for conjugal transfer; orange arrows represent genes coding for maintenance and stability; gray arrows represent genes coding for hypothetical proteins. Homologous segments generated by a BLASTn comparison (≥94% identity of nucleotide sequence) are shown as grey boxes