禽源奇异变形杆菌质粒介导AmpC酶基因型检测与质粒分析

赵世玉,焦嘉杰,董宁宁,潘圆月,崔孟梅,潘玉善

Analysis of Plasmid-Mediated AmpC β-lactamases Gene and Plasmid in Poultry Proteus mirabilis Strains

ZHAO ShiYu,JIAO JiaJie,DONG NingNing,PAN YuanYue,CUI MengMei,PAN YuShan

表2 12种抗菌药物对6株blaCMY-2阳性禽源奇异变形杆菌及接合子TC12的MIC值

Table 2 MICs of twelve antimicrobials against six blaCMY-2-carrying Proteus mirabilis strains and the transconjugant TC12 (µg·mL-1)

抗菌药物 Antimicrobial agents MICs (µg·mL-1) 菌株 Strains CY12 CY32 WS2 S31 S52 C12 TC12 E. coli C600 E. coli ATCC 25922 氨苄西林Ampicillin >256 >256 >256 >256 >256 >256 256 4 2 头孢他啶Ceftazidime 8 8 4 4 4 2 2 <0.125 <0.125 头孢噻肟Cefotaxime 4 1 2 2 2 4 4 <0.125 <0.125 头孢西丁Cefoxitin 32 32 64 32 32 32 32 2 2 环丙沙星Ciprofloxacin 4 4 1 8 8 4 <0.125 <0.125 <0.125 恩诺沙星Enrofloxacin 16 16 4 32 32 32 <0.125 <0.125 <0.125 卡那霉素Kanamycin 256 256 2 >256 128 128 64 4 4 阿米卡星Amikacin 4 2 0.5 8 4 1 1 <0.125 <0.125 庆大霉素Gentamycin 8 16 0.25 2 2 64 32 <0.125 <0.125 氟苯尼考Florfenicol >256 256 8 128 128 64 128 2 0.5 多西环素Doxycycline 128 64 128 64 64 64 64 0.25 <0.125 粘菌素Colistin >256 >256 >256 >256 >256 >256 <0.125 <0.125 <0.125