蜂胶提取物对脂多糖诱导小鼠急性乳腺炎及乳腺屏障功能的保护作用

宋美洁,欧爱群,薛晓锋,吴黎明,寿旗扬,王凯

Protective Effects of Chinese Propolis Extract Against Lipopolysaccharide- Induced Acute Mastitis and Mammary Barrier Functions in Mice

SONG MeiJie,OU AiQun,XUE XiaoFeng,WU LiMing,SHOU QiYang,WANG Kai

表5 中国蜂胶乙醇提取物中主要的多酚类物质成分

Table 5 Major polyphenolic constituents in EECP

多酚类化合物 Polyphenolic compound 分子式 Molecular formula 保留时间 Rt (min) 母离子 Parention 含量 Content (μg·mg-1) 咖啡酸Caffeic Acid C9H8O4 5.487 179.035 3.23±0.03 p-香豆酸 p-Coumaric acid C9H8O3 6.109 163.0401 - 阿魏酸 Ferulic Acid C10H10O4 6.304 193.0506 - 咖啡酸苯乙酯 Caffeic acid phenethyl ester C17H16O4 9.503 283.0976 2.49±0.06 芹菜素 Apigenin C15H10O5 7.718 269.0455 1.68±0.08 柯因Chrysin C15H10O4 9.363 253.0506 7.71±1.01 槲皮素 Quercetin C15H10O7 7.225 301.0354 1.51±0.05 高良姜素 Galangin C15H10O5 9.547 269.0455 12.88±0.57 桑色素 Morin C15H10O7 6.919 301.0354 - 松属素 Pinocembrin C15H12O4 9.461 255.0663 8.56±0.27 短叶松素 Pinobanksin C15H12O5 8.000 271.0612 8.52±0.25 芦丁Rutin C27H30O16 5.599 609.1461 - 短叶松素三乙酸酯 Pinobanksin-3-acetate C17H14O6 9.609 313.0718 12.93±0.59 杨梅素 Myricetin C15H10O8 6.580 317.0303 0.81±0.06 香草酸 Vanillic acid C8H8O4 5.597 167.035 0.72±0.01 柚皮素 Naringenin C15H12O5 7.767 271.0612 - 3,4-二甲氧基肉桂酸 3,4-Dimethoxycinnamic acid C11H12O4 7.120 207.0663 3.49±1.23