限制性两阶段多位点全基因组关联分析法在遗传育种中的应用
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贺建波,刘方东,王吴彬,邢光南,管荣展,盖钧镒
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Restricted Two-Stage Multi-Locus Genome-Wide Association Analysis and Its Applications to Genetic and Breeding Studies
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JianBo HE,FangDong LIU,WuBin WANG,GuangNan XING,RongZhan GUAN,JunYi GAI
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表3 基于大豆NAM群体的五种QTL定位方法特点归纳比较
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Table 3 Comparisons of five QTL detection procedures based on soybean NAM population
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比较指标
Item | 独立分析 Separate mapping | 联合分析Joint mapping | | CIM[3] | MCIM[24] | JICIM[25] | MLM[26] | RTM-GWAS | 标记类型
Marker type | BIN | BIN | SNP | SNP | SNPLDB | 定位原理
Mapping mechanism | 连锁定位
Linkage mapping | 连锁定位
Linkage mapping | 连锁定位
Linkage mapping | 关联定位
Association mapping | 关联定位
Association mapping | QTL数量
Number of QTLs | 8 | 16 | 9 | 7 | 139 | 等位基因数量
Number of alleles | 2 | 2 | 8 | 2 | 2~5 | 遗传贡献率
Genetic contribution (%) | 73.2—96.1 | 48.4—94.5 | 74.0 | 40.6 | 81.7 | 表型数据类型
Phenotype data | 平均数
Entry mean | 小区观测值
Single plot | 平均数
Entry mean | 平均数
Entry mean | 小区观测值
Single plot | QTL×环境互作
QTL×Env. | 否No | 是Yes | 否No | 否No | 是Yes | 计算机软件
Software | QTL Cartographer | QTLNetwork | QTL IciMapping | TASSEL | RTM-GWAS | 命令行界面
Command line | 是Yes | 否No | 否No | 是Yes | 是Yes | | 计算平台Platform | Windows/Linux | Windows | Windows | Windows/Linux/Mac | Windows/Linux/Mac |
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