微小RNA介导东方蜜蜂微孢子虫侵染意大利蜜蜂工蜂的分子机制

耿四海,石彩云,范小雪,王杰,祝智威,蒋海宾,范元婵,陈华枝,杜宇,王心蕊,熊翠玲,郑燕珍,付中民,陈大福,郭睿

The Mechanism Underlying MicroRNAs-Mediated Nosema ceranae Infection to Apis mellifera ligustica Worker

GENG SiHai,SHI CaiYun,FAN XiaoXue,WANG Jie,ZHU ZhiWei,JIANG HaiBin,FAN YuanChan,CHEN HuaZhi,DU Yu,WANG XinRui,XIONG CuiLing,ZHENG YanZhen,FU ZhongMin,CHEN DaFu,GUO Rui

表3 各比较组中DEmiRNA的靶mRNA富集的前15条通路

Table 3 Top 15 pathways enriched by DEmiRNA target mRNAs in each comparison group

通路 Pathway NcCK vs NcT1比较组 NcCK vs NcT1 group NcCK vs NcT2比较组 NcCK vs NcT2 group NcT1 vs NcT2比较组 NcT1 vs NcT2 group 新陈代谢途径 Metabolic pathways 119 113 103 核糖体 Ribosome 56 50 41 次生代谢产物合成 Biosynthesis of secondary metabolites 48 47 42 真菌生物核糖体的生物合成 Ribosome biogenesis in eukaryotes 37 38 29 抗生素的生物合成 Biosynthesis of antibiotics 36 35 31 内质网蛋白质加工 Protein processing in endoplasmic reticulum 35 32 29 嘌呤代谢 Purine metabolism 33 28 26 嘧啶代谢 Pyrimidine metabolism 32 28 25 细胞周期 Cell cycle 31 30 28 RNA转运 RNA transport 30 26 24 蛋白酶体 Proteasome 28 25 24 减数分裂 Meiosis 26 24 24 mRNA监督通路 mRNA surveillance pathway 24 21 22 DNA复制 DNA replication 24 24 22 泛素蛋白水解 Ubiquitin mediated proteolysis 24 24 20