液相色谱-串联质谱法同时测定饲用血液制品中 18种β-受体激动剂

索德成,魏书林,肖志明,王培龙,王瑞国,李阳

Simultaneous Determination of 18 β-agonists in Blood Products for Feeds by Liquid Chromatography Tandem Mass Spectrometry

DeCheng SUO,ShuLin WEI,ZhiMing XIAO,PeiLong WANG,RuiGuo WANG,Yang LI

表3 β-受体激动剂标准溶液线性、LOQ,㎏LOD

Table 3 Linear, LOQ,LOD of β-agonists

药物名称Drug type 线性方程Linear 相关系数R 检出限LOQ 定量限LOD 沙丁胺醇Salbutamol Y=1269.565×X-406.66 0.9978 1.3 5 克仑特罗Clenbuterol Y=3014.721×X-4337.78 0.9953 0.26 1 莱克多巴胺Ractopamine Y=1160.984×X-3517.6 0.9984 1.7 5 苯乙醇胺A Phenylethanolamine A Y=1097.357×X+2264.901 0.9925 0.47 2 溴布特罗Brombuterol Y=1416.301×X-5076.61 0.9948 0.43 2 氯丙那林Clorprenaline Y=3073.42×X-9732.25 0.9944 1.6 5 特布他林Terbutaline Y=253.3226×X+991.6666 0.9997 1.8 5 齐帕特罗Zilpaterol Y=122.7947×X-67.6185 0.9967 1.7 5 马布特罗Mabuterol Y=5759.203×X-20240.1 0.9970 1.3 5 西马特罗Cimaterol Y=1269.431×X-3962.79 0.9932 1.6 5 班布特罗Bambuterol Y=16871.19×X-61885.9 0.9950 0.35 1 妥布特罗Tulobuterol Y=1919.729×X+2687.591 0.9958 1.7 5 克仑普罗Clenproperol Y=2043.752×X-7385.5 0.9971 1.3 5 福莫特罗Formoterol Y=1695.161×X-6568.26 0.9982 0.42 1 西布特罗Cimbuterol Y=1917.388×X-5613.98 0.9936 1.3 5 沙美特罗Salmeterol Y=1223.231×X+2729.52 0.9954 1.8 5 利托君Ritodrine Y=1238.231×X+272.34 0.9954 0.27 1 克伦塞罗Clencyclohexerol Y=1153.31×X+1911.66 0.9994 1.8 5