代谢组学在农产品营养品质检测分析中的应用

许彦阳,姚桂晓,刘平香,赵洁,王昕璐,孙君茂,钱永忠

Review on the Application of Metabolomic Approaches to Investigate and Analysis the Nutrition and Quality of Agro-Products

YanYang XU,GuiXiao YAO,PingXiang LIU,Jie ZHAO,XinLu WANG,JunMao SUN,YongZhong QIAN

续表1 代谢组学在农产品营养品质检测分析中的应用

Table 1 Applications of Metabolomics to investigate and analysis nutrition and quality of agro-products（Continued）

应用 Application 农产品种类 Agro-product 检测技术 Detection technology 数据处理方法 Data analysis 生物标志物 Biomarker 参考文献 Reference 榛子 Hazelnut LC-ESI-QqQ-MS PCA-LDA, ANOVA PE(18:2/18:2) (1,2-dilinoleoyl-sn glycero-3- phosphoethanolamine)、PC(18:2/18:2) (1,2- dilinoleoyl-sn-glycero-3-phosphocholine)、DG (18:2/18:2) (1,3-100 dilinoleoyl-rac-glycerol) [91] 生长储藏过程中营养成分变化规律 Changes of nutritional components during growth and storage 草莓 Strawberry GC-MS,HPLC-MS PCA, PLS-DA 游离氨基酸(Free amino acids) [92] 葡萄 Grapevine berry GC-MS HCA, PCA, PLS-DA, ANOVA 糖类(Sugars)和氨基酸(Amino acids) [93] 番茄 Tomato GC-MS PLS-DA, ANOVA 甘露糖(Mannose)、柠檬酸(Citramalic)、葡萄糖酸(Gluconic)和酮-1-古洛糖酸(Keto-l-gulonic acids)等 [94] 鸡蛋 Chicken eggs HPLC-QTOF-MS PCA 胆碱(Choline) [48] 大豆 Soybean 1H-NMR PCA, PLS-DA 脯氨酸(Proline)、赖氨酸(Lysine)和硫(Sulfur) [96] 营养功能成分作用机制及对代谢的影响 Functional mechanism of nutritional components and their effects on metabolism 生姜 Ginger HPLC-QTOF-MS ANOVA D-葡糖醛酸-6 (D-glucurono-6)、3-内酯(3- lactone)、甘油-3-磷酸(Glycerol-3-phosphate)、丙酮酸(Pyruvic acid)、石胆酸(Lithocholic acid)、2-吡啶甲酸(2-pyrocatechuic acid)和前列腺素E1 (Prostaglandin El)等 [100] 枸杞 Lycium barbarum GC-TOF-MS PCA, OPLS-DA 丙氨酸(Alanine)、胸腺嘧啶脱氧核苷酸(Thymidine deoxynucleotide) [101] 绿茶 Green tea LC-MS PCA, OPLS-DA, PLS regression analysis 多酚(Polyphenol) [102] 苦瓜 Bitter gourd NMR PCA, PLS-DA 柠檬酸(Citramalic)、琥珀酸(Succinate)、肌氨酸(Sarcosine)、丙酮酸(Pyruvic acid)等 [107] 白茶 Origanum dictamnus tea 1H-NMR PCA, OPLS-DA 马尿酸(Hippurate)和肌酐(Creatinine) [108] 饮食模式 Dietary modulation 1H-NMR OPLS-DA 肉碱(Carnitine)、乙酰肉碱(Acetylcarnitine)、三甲胺-N-氧化物(Trimethylamine-N-oxid)、对-羟基苯乙酸酯(p-hydroxyphenylacetate) [109]