PK-15细胞中与CSFV感染相关的microRNAs筛选及 miR-214的功能研究

邓少锋,叶佐东,范双旗,陈金顶,张静远,朱梦娇,赵明秋

Screen of MicroRNAs in Classical Swine Fever Virus-Infected PK-15 Cells and the Regulation of Virus Replication by miR-214

ShaoFeng DENG,ZuoDong YE,ShuangQi FAN,JinDing CHEN,JingYuan ZHANG,MengJiao ZHU,MingQiu ZHAO

表2 CSFV感染PK-15细胞后表达下调的miRNA

Table 2 The down-regulated miRNAs in CSFV-infected PK-15 cells

编号 ID miRNA名称 Name log2比率 log2 ratio P值 P-value MIMAT0025385 ssc-miR-1249 -2.15272 0.00001 MIMAT0013934 ssc-miR-361-3p -1.95208 0.00001 MIMAT0017952 ssc-miR-296-5p -1.05927 0.00001 MIMAT0013937 ssc-miR-1306-5p -0.95394 0.00001 MIMAT0013941 ssc-miR-532-3p -0.68756 0.00001 MIMAT0017980 ssc-miR-4339 -0.6224 0.00001 MIMAT0013871 ssc-miR-30d -0.30603 0.00001 MIMAT0002165 ssc-miR-21 -0.27854 0.00001 MIMAT0025381 ssc-miR-671-5p -0.2569 0.00001 MIMAT0017974 ssc-miR-484 -0.248 0.00001 MIMAT0020586 ssc-miR-129b -0.22805 0.00008 MIMAT0018379 ssc-miR-149 -0.21029 0.00004 MIMAT0015708 ssc-miR-744 -0.20892 0.00386 MIMAT0017965 ssc-miR-1224 -0.18271 0.00033 MIMAT0013900 ssc-miR-345-3p -0.17812 0.00828 MIMAT0025365 ssc-miR-150 -0.15152 0.00775 MIMAT0020596 ssc-miR-1343 -0.14743 0.00461 MIMAT0013935 ssc-miR-1277 -0.13761 0.00482 MIMAT0010186 ssc-miR-133a-3p -0.13388 0.03942 MIMAT0013959 ssc-miR-129a -0.12737 0.01689 MIMAT0013939 ssc-miR-339-5p -0.11957 0.01352 MIMAT0025384 ssc-miR-874 -0.11957 0.00046 MIMAT0028147 ssc-miR-7136-5p -0.11865 0.00367 MIMAT0013909 ssc-miR-92b-3p -0.10387 0.02389 MIMAT0017962 ssc-miR-4332 -0.09669 0.03493 MIMAT0013918 ssc-miR-425-3p -0.09066 0.00617 MIMAT0013869 ssc-miR-133b -0.08309 0.00758 MIMAT0013904 ssc-miR-365-3p -0.06645 0.03768 MIMAT0022958 ssc-miR-296-3p -0.06567 0.04572 MIMAT0013947 ssc-miR-935 -0.05012 0.01506