PK-15细胞中与CSFV感染相关的microRNAs筛选及 miR-214的功能研究

邓少锋,叶佐东,范双旗,陈金顶,张静远,朱梦娇,赵明秋

Screen of MicroRNAs in Classical Swine Fever Virus-Infected PK-15 Cells and the Regulation of Virus Replication by miR-214

ShaoFeng DENG,ZuoDong YE,ShuangQi FAN,JinDing CHEN,JingYuan ZHANG,MengJiao ZHU,MingQiu ZHAO

表1 CSFV感染PK-15细胞后表达量上调的miRNA

Table 1 The up-regulated miRNAs in CSFV-infected PK-15 cells

编号 ID miRNA名称 Name log2比率 log2 ratio P值 P-value MIMAT0006786 ssc-miR-140-3p 0.48443 0.00026 MIMAT0002147 ssc-miR-214 0.42896 0.00001 MIMAT0013955 ssc-miR-335 0.38587 0.00001 MIMAT0002120 ssc-miR-125b 0.09519 0.00043 MIMAT0025368 ssc-miR-194a 0.31888 0.01203 MIMAT0013944 ssc-miR-342 0.31845 0.03668 MIMAT0010192 ssc-miR-215 0.30804 0.04995 MIMAT0022956 ssc-miR-202-3p 0.29007 0.00009 MIMAT0007759 ssc-miR-185 0.22220 0.00035 MIMAT0013912 ssc-miR-208b 0.21017 0.00771 MIMAT0013876 ssc-miR-191 0.20254 0.03214 MIMAT0025360 ssc-miR-31 0.20020 0.01347 MIMAT0002119 ssc-miR-122 0.19622 0.01318 MIMAT0007758 ssc-miR-130a 0.19402 0.02421 MIMAT0013916 ssc-miR-34c 0.19369 0.01302 MIMAT0017385 ssc-miR-1839-3p 0.19364 0.03377 MIMAT0013906 ssc-miR-664-5p 0.16827 0.00425 MIMAT0013880 ssc-miR-423-5p 0.16298 0.00001 MIMAT0002134 ssc-miR-24-3p 0.16088 0.01132 MIMAT0007757 ssc-miR-34a 0.16044 0.00131 MIMAT0017956 ssc-miR-382 0.15206 0.00146 MIMAT0013954 ssc-miR-1285 0.14589 0.04690 MIMAT0025356 ssc-let-7d-5p 0.14434 0.01134 MIMAT0017376 ssc-miR-365-5p 0.14349 0.03370 MIMAT0028156 ssc-miR-7140-3p 0.13804 0.00007 MIMAT0015300 ssc-miR-30a-3p 0.13721 0.02233 MIMAT0028144 ssc-miR-7134-3p 0.13182 0.00483 MIMAT0013956 ssc-miR-500 0.13164 0.02126 MIMAT0013910 ssc-miR-192 0.12760 0.00862 MIMAT0013922 ssc-miR-130b 0.12228 0.02580 MIMAT0013903 ssc-miR-885-3p 0.11877 0.00246 MIMAT0022921 ssc-miR-139-3p 0.11860 0.00302 MIMAT0028152 ssc-miR-7138-3p 0.11640 0.03755 MIMAT0006018 ssc-miR-99b 0.11097 0.01450 MIMAT0028155 ssc-miR-7140-5p 0.09369 0.00232 MIMAT0013920 ssc-miR-424-5p 0.09366 0.00090 MIMAT0022922 ssc-miR-30c-3p 0.08348 0.01393 MIMAT0013894 ssc-miR-193a-5p 0.08314 0.00302 MIMAT0010188 ssc-miR-450a 0.03115 0.00119