OVATE家族蛋白（OFPs）是一类植物中特有的调控生长发育的蛋白，在一些物种中已经被研究报道，但在黄瓜中的生物学功能还不清楚。我们在黄瓜中鉴定出19个CsOFPs。这些基因在黄瓜的7条染色体上均有分布。大多数在生殖器官中有表达，但表达模式具有差异性。在拟南芥中异源过表达CsOFP12-16c导致果实变短，末端钝圆。以上研究表明CsOFP12-16c在拟南芥中调节角果的发育，在黄瓜中可能参与了果实形状的调控。

Low temperature and high salinity are the major abiotic stresses that restrict cucumber growth and production, breeding materials with multiple abiotic resistance are in greatly need. Here we investigated the effect of introducing the LOS5 gene, a key regulator of ABA biosynthesis in Arabidopsis thaliana, under the stress-responsive RD29A promoter into cucumber (Cucumis sativus L. cv. S516). We found that T1 RD29A-LOS5 transgenic lines have enhanced tolerance to cold and salt stresses. Specifically, transgenic lines exhibited dwarf phenotypes with reduced leaf number, shorter internode, decreased length of the biggest leaf, fewer female flowers, shorter fruit neck and lower vitamin C (Vc). The increased cold tolerance can be reflected from the significantly decreased cold index, the reduced electrolyte leakage index and the MDA content upon cold treatment as compared to those in the control. This may result from the accumulation of internal ABA, soluble sugars and proline, and the enhanced activities of protective enzymes superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) in the transgenic lines. Under salt treatment, the transgenic lines exhibited increased germination index, vigor index, more lateral roots and increased root fresh weight. Moreover, RD29A-LOS5 transgenic plants displayed quicker responses in salt stress than that in low-temperature stress.