Cardiopulmonary, Biochemical and Haematological Effects of the Tiletamine/ Zolazepam-Xylazine-Tramadol Combination to Provide Anaesthesia in Miniature Pigs

doi:10.1016/S1671-2927(00)8664

Journal of Integrative Agriculture ›› 2012, Vol. 12 ›› Issue (8): 1340-1346.DOI: 10.1016/S1671-2927(00)8664

Cardiopulmonary, Biochemical and Haematological Effects of the Tiletamine/ Zolazepam-Xylazine-Tramadol Combination to Provide Anaesthesia in Miniature Pigs

LU De-zhang, FAN Hong-gang, JIANG Sheng, ZHANG Luan-song, MA Kun, YU Shi-ming, TAN Lijuan, WANG Hong-bin

1.Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P.R.China
2.Department of Veterinary Surgery, College of Veterinary Medicine, Northwest Agricultrue and Forestry University, Yangling 712100, P.R.China

收稿日期:2011-08-19 出版日期:2012-08-01 发布日期:2012-09-09
通讯作者: Correspondence WANG Hong-bin, Tel: +86-451-55191833, Fax: +86-451-55190470, E-mail: hbwang1940@yahoo.com.cn
基金资助:
This study supported by the National Natural Science Foundation of China (30671552 and 30972227).

Cardiopulmonary, Biochemical and Haematological Effects of the Tiletamine/ Zolazepam-Xylazine-Tramadol Combination to Provide Anaesthesia in Miniature Pigs

LU De-zhang, FAN Hong-gang, JIANG Sheng, ZHANG Luan-song, MA Kun, YU Shi-ming, TAN Lijuan, WANG Hong-bin

1.Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P.R.China
2.Department of Veterinary Surgery, College of Veterinary Medicine, Northwest Agricultrue and Forestry University, Yangling 712100, P.R.China

Received:2011-08-19 Online:2012-08-01 Published:2012-09-09
Contact: Correspondence WANG Hong-bin, Tel: +86-451-55191833, Fax: +86-451-55190470, E-mail: hbwang1940@yahoo.com.cn
Supported by:
This study supported by the National Natural Science Foundation of China (30671552 and 30972227).

摘要/Abstract

摘要： The objective of this study was to investigate the suitability of tiletamine/zolazepam-xylazine-tramadol combination for miniature pigs. Fourteen Chinese experimental miniature pigs subjected to this study received 3.5 mg tiletamine/zolazepam kg-1 bw, 1.32 mg xylazine kg-1 bw and 1.8 mg tramadol kg-1 bw intramuscularly, as a mixture of the drugs. Cardiopulmonary, biochemical and haematological parameters were recorded before drug administration and after anaesthesia. The combination of the compounds resulted in anaesthesia lasting about 87 min and a satisfactory immobilization for handling. Cardiopulmonary parameters were changed after administration, but there were within biologically acceptable limits. Biochemical and haematological values decreased after drug administration, however, they returned to the baseline at 24 h. At the doses described, tiletamine/zolazepam-xylazine-tramadol combination produced good immobilization in miniature pigs with minimal changes over time in cardiopulmonary, biochemical and haematological parameters.

关键词: cardiopulmonary, tiletamine/zolazepam-xylaxine-tramadol combination, anaesthesia, miniature pigs

Abstract: The objective of this study was to investigate the suitability of tiletamine/zolazepam-xylazine-tramadol combination for miniature pigs. Fourteen Chinese experimental miniature pigs subjected to this study received 3.5 mg tiletamine/zolazepam kg-1 bw, 1.32 mg xylazine kg-1 bw and 1.8 mg tramadol kg-1 bw intramuscularly, as a mixture of the drugs. Cardiopulmonary, biochemical and haematological parameters were recorded before drug administration and after anaesthesia. The combination of the compounds resulted in anaesthesia lasting about 87 min and a satisfactory immobilization for handling. Cardiopulmonary parameters were changed after administration, but there were within biologically acceptable limits. Biochemical and haematological values decreased after drug administration, however, they returned to the baseline at 24 h. At the doses described, tiletamine/zolazepam-xylazine-tramadol combination produced good immobilization in miniature pigs with minimal changes over time in cardiopulmonary, biochemical and haematological parameters.

Key words: cardiopulmonary, tiletamine/zolazepam-xylaxine-tramadol combination, anaesthesia, miniature pigs

LU De-zhang, FAN Hong-gang, JIANG Sheng, ZHANG Luan-song, MA Kun, YU Shi-ming, TAN Lijuan, WANG Hong-bin. Cardiopulmonary, Biochemical and Haematological Effects of the Tiletamine/ Zolazepam-Xylazine-Tramadol Combination to Provide Anaesthesia in Miniature Pigs[J]. Journal of Integrative Agriculture, 2012, 12(8): 1340-1346.

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Cardiopulmonary, Biochemical and Haematological Effects of the Tiletamine/ Zolazepam-Xylazine-Tramadol Combination to Provide Anaesthesia in Miniature Pigs

Cardiopulmonary, Biochemical and Haematological Effects of the Tiletamine/ Zolazepam-Xylazine-Tramadol Combination to Provide Anaesthesia in Miniature Pigs

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