[1]Gray N K, Wickens M. Control of translation initiation in animals. Annual Review of Cell Biology, 1998, 14: 399-458. [2]刘海燕, 许文涛, 罗云波, 王洪新, 黄昆仑. 动物实验评价转基因食品食用安全的研究进展. 农业生物技术学报, 2010, 18(4): 793-800.Liu H Y, Xu W T, Luo Y B, Wang H X, Huang K L. Research progress on assessment of genetically modified food safety by animal experiment. Journal of Agricultural Biotechnology, 2010, 18(4): 793-800.[3]Li M A, Turner D J, Ning Z, Yusa K, Liang Q, Eckert S, Rad L, Fitzgerald T W, Craig N L, Bradley A. Mobilization of giant piggyBac transposons in the mouse genome. Nucleic Acids Research, 2011, 39(22): e148. [4]Macejak D G, Sarnow P. Internal initiation of translation mediated by the 5′ leader of a cellular mRNA. Nature, 1991, 353(6339): 90-94.[5]de Felipe P. Skipping the co-expression problem: the new 2A “CHYSEL” technology. Genetic Vaccines and Therapy, 2004, 2: 13-18.[6]赵 青, 郭仰东, 谢 华, 马荣才, 姚 磊. 基于AlcR/alcA和Cre/loxP 系统的标记基因诱导删除体系. 中国农业科学, 2011, 44(17): 3491-3500.Zhao Q, Guo Y D, Xie H, Ma R C, Yao L. Excision of selectable markers based on inducible AlcR/alcA and Cre/loxP systems. Scientia Agricultura Sinica, 2011, 44(17): 3491-3500.[7]张晓曼, 刘新生, 许予明, 李艾帆. SV40 LT 基因诱导人骨髓间充质干细胞的实验研究. 中风与神经疾病杂志, 2009, 26(5): 545-547.Zhang X M, Liu X S, Xu Y M, Li A F. Immortalization of human bonemarrow mesenchymal stem cells by transfected with SV40LT genes. Apoplexy and Nervous Diseases, 2009, 26(5): 545-547.[8]Hermannstädter A, Ziegler C, Kuhl M, Deppert W, Tolstonog G. Wild-type p 53 enhances efficiency of simian virus 40 large-T- antigen-induced cellular transformation. Journal of Virology, 2009, 83(19): 10106-10118.[9]Higuchi R, Krummel B, Saiki R K. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Research, 1988, 16(15): 7351-7367.[10]Lottmann H, Vanselow J, Hessabi B, Walther R. The Tet-On system in transgenic mice: inhibition of the mouse pdx-1 gene activity by antisense RNA expression in pancreatic beta-cells. Journal of Molecular Medicine, 2001, 79(5/6): 321-328.[11]丁 昇. PiggyBac转座系统[D]. 上海: 复旦大学, 2007. Ding S. PiggyBac transposon system[D]. Shanghai: Fudan University, 2007.[12]Pechan P A, Herrlinger U, Aghi M, Jacobs A, Breakefield X O.Combined HSV-1 recombinant and amplicon piggyback vectors: replication-competent and defective forms, and therapeutic efficacy for experimental gliomas. The Journal of Gene Medicine, 1999, 1(3): 176-85.[13]Kang Y, Zhang X Y, Jiang W, Wu C Q, Chen C M, Gu JR, Zheng Y F, Xuf C J. The piggyback transposon is an integrating non-viral gene transfer vector that enhances the efficiency of GDEPT. Cell Biology International, 2009, 33(4): 509-515.[14]Ding S, Wu X, Li G, Han M, Zhuang Y, Xu T. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell, 2005, 122(3): 473-483.[15]Clark K J, Carlson D F, Foster L K, Kong B W, Foster D N, Fahrenkrug S C. Enzymatic engineering of the porcine genome with transposons and recombinases. BMC Biotechnology, 2007, 17(7): 42-48.[16]Martin P, Albagli O, Poggi M C, Boulukos K E, Pognonec P. Development of a new bicistronic retroviral vector with strong IRES activity. BMC Biotechnology, 2006, 6(4): 1-9.[17]Li T, Zhang J. Stable expression of three genes from a tricistronic retroviral vector containing a picornavirus and 9-nt cellular internal ribosome entry site elements. Journal of Virological Methods, 2004, 115(2): 137-144.[18]Donnelly M L, Hughes L E, Luke G, Mendoza H, Dam E, Gani D, Ryan M. The ‘cleavage’ activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring ‘2A-like’ sequences. Journal of General Virology, 2001, 82(Pt 5): 1027-1041.[19]De Felipe P, Luke G A, Hughes L E, Gani D, Halpin H, Ryan D. E unum pluribus: multiple proteins from a self-processing polyprotein. Trends in Biotechnology, 2006, 24(2): 68-75.[20]Osborn M J, Panoskaltsis-Mortari A, McElmurry R T, Bell S K, Vignali D A, Ryan D, Wilber A, McIvor R S, Tolar J, Blazar B R. A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system. Molecular Therapy, 2005, 12(3): 569-574.[21]Woltjen K, Kosuke Y, Roland R, Junji T, Lan B. Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon. Nature methods, 2009, 6(5): 363-369.[22]Woltjen K, Michael I P, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, Cowling R, Wang W, Liu P T, Gertsenstein M, Kaji K, Sung H K, Nagy A. PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature, 2009, 458: 766-770.[23]Zhu J Y, Abate M, Rice P W, Cole C N. The ability of simian virus 40 large T antigen to immortalize primary mouse embryo fibroblasts cosegregates with its ability to bind to p53. Journal of Virology, 1991, 65(12): 6872-6880.[24]Maruyama M, Kobayashi N, Westerman K A, Masakiyo, Jean A, Toshinori T, Teru O, Takuya F, Anne W, Donna S, Philippe L, Noriaki T. Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT. Transplantation, 2004, 77(3): 446-451.[25]张文娟, 于丹妮, 韩育植, 任志明. 利用Cre/loxP系统构建无标记的htrA基因缺失的变链菌突变株. 天津医药, 2011, 39(2): 108-111.Zhang W J, Yu D N, Han Y Z, Ren Z M. Construction of unmarked HtrA-deficient mutant of streptococcus mutans with Cre/loxP system. Tianjin Medicine Journal, 2011, 39(2): 108-111. |