抗菌肽的功能、研发与应用

doi:10.3864/j.issn.0578-1752.2012.11.014

摘要/Abstract

摘要： 抗菌肽（antimicrobial peptides，AMPs）广泛存在于多种生物体内，是生物体非特异性免疫功能的重要组成部分，具有抗细菌、真菌、病毒等多种生物学功能。由于其特殊的杀菌机制而使得细菌不易产生耐药性，在多个领域显示了良好的应用前景。本文综述了抗菌肽的类别、生物学功能及其抑菌机制，重点阐述了近年来抗菌肽研发与应用的国内外进展。

关键词: 抗菌肽, 功能, 研发, 应用, 动物

Abstract: Antimicrobial peptides (AMPs) distribute widely in all organisms. As an important part of the non-specific immune functions of organisms, AMPs process the properties of various biological functions and low tendency of developing drug resistance and have a potential application prospect in many fields. This review deals with classification, biofunction and antibacterial mechanism of AMPs, particularly summurizes the research progess in the exploitation and application of AMPs in animals in recent years.

Key words: antimicrobial peptitides, function, exploitation, application, animals

单安山, 马得莹, 冯兴军, 马清泉, 董娜, 王良, 吕银凤, 朱鑫. 抗菌肽的功能、研发与应用[J]. 中国农业科学, 2012, 45(11): 2249-2259.

DAN An-Shan, MA De-Ying, FENG Xing-Jun, MA Qing-Quan, DONG Na, WANG Liang, 吕Yin-Feng , ZHU Xin. Function, Research, and Application of Antimicrobial Peptides[J]. Scientia Agricultura Sinica, 2012, 45(11): 2249-2259.

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