中国农业科学 ›› 2010, Vol. 43 ›› Issue (5): 1075-1082 .doi: 10.3864/j.issn.0578-1752.2010.05.024

• 兽医 • 上一篇    下一篇

鸡INR的神经束与血-神经屏障的超微结构

柳金雄,王江,杨平,冯亚玫,徐春生,包慧君,陈秋生

  

  1. (南京农业大学动物医学院)
  • 收稿日期:2009-04-20 修回日期:2009-08-22 出版日期:2010-03-01 发布日期:2010-03-01
  • 通讯作者: 陈秋生

Ultrastructural Investigation on Nerve Tract and Blood-Nerve Barrier of Intestinal Nerve of Remak in Chicken

LIU Jin-xiong, WANG Jiang, YANG Ping, FENG Ya-mei, XU Chun-sheng, BAO Hui-jun, CHEN Qiu-sheng
  

  1. (南京农业大学动物医学院)
  • Received:2009-04-20 Revised:2009-08-22 Online:2010-03-01 Published:2010-03-01
  • Contact: CHEN Qiu-sheng

摘要:

【目的】研究鸡肠Remak神经(INR)神经束的超微构造与血-神经屏障的微细形态,为进一步阐明INR的生理功能提供理论基础。【方法】应用透射电镜技术研究鸡肠Remak神经(INR)神经束的超微构造与血-神经屏障的微细形态。【结果】鸡INR被神经束膜分隔成许多神经束,束内既有无髓纤维又有有髓纤维,但以无髓神经纤维的数量占绝对优势。雪旺氏细胞与两种神经纤维的形成与结构密切相关。神经束膜细胞突起长而薄,包绕神经束,其丰富的粗面内质网、线粒体和发达高尔基复合体,以及以常染色质为主的细胞核和明显的核仁结构,提示束膜细胞具有活跃的蛋白合成和分泌功能。不同于肠壁内ENS缺乏神经屏障的现象,鸡INR的神经束膜中分布有血-神经屏障,是由结构紧密的毛细血管及其周围多层排列的束膜细胞形成的,且束膜细胞表面可见吞饮泡的形成,但未见不同束膜细胞之间有特殊的细胞连接。这种组成特点表明,鸡INR的血-神经屏障没有哺乳动物外周神经的严密。【结论】上述试验结果显示,鸡INR的细胞学结构既不同于肠壁内ENS,也与外周神经有差异,具有一定的特殊性。

关键词: 鸡, INR, 神经束, 血-神经屏障, 超微结构

Abstract:

【Objective】 The objective of the experiment is to detect the morphological feature, fine structure of nerve tract and blood-nerve barrier of the intestinal nerve of Remak (INR). 【Method】 INR of chicken was examined by the transmission electron microscopy. 【Result】Results showed that INR was divided by the perineurium into many nerve tracts. Unmyelinated nerve fibers dominated in number in each nerve tract although there were both myelinated and unmyevinated nerve fibers there. Schwann’s cells were related to the development and structure of the two fiber types. Each nerve tract was surrounded by the perineural cell with long and thin processus. The rough endoplasmic reticulum, mitochondrion and Golgi complex were developed and the euchromatin was dominated in the nucleus with a conspicuous nucleolus in the perineural cell, which indicated that the perineural cell engaged in active protein synthesis and secretion. Although the ENS in intestinal wall lacks blood-nerve barrier, there were the barriers in the INR, which consisted of tight capillary and surrounding layers of the perineural cells. Pinocytotic vesicles developed on surface of the perineural cell, whereas special cell junctions between the cells were not seen, which suggested that the blood-nerve barrier of the INR in chickens was not closer than that of peripheral nerve system in mammals. 【Conclusion】 All the results above revealed that the cytological natures of the INR in the chicken were special, which is different from either the ENS in the intestinal wall or the peripheral nerve.

Key words: chicken, intestinal nerve of Remak (INR), nerve tract, blood-nerve barrier, ultrastructure